Zobrazeno 1 - 10
of 409
pro vyhledávání: '"Diabetes Mellitus/metabolism"'
Autor:
Dogan Grepper, Cassandra Tabasso, Axel K.F. Aguettaz, Adrien Martinotti, Ammar Ebrahimi, Sylviane Lagarrigue, Francesca Amati
Publikováno v:
Molecular metabolism, vol. 68, pp. 101669
Ectopic lipid accumulation is a hallmark of metabolic diseases, linking obesity to non-alcoholic fatty liver disease, insulin resistance and diabetes. The use of zebrafish as a model of obesity and diabetes is raising due to the conserved properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b373364c39de5abc82c28d008fc85153
https://serval.unil.ch/resource/serval:BIB_BE4D18023E2B.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_BE4D18023E2B.P001/REF.pdf
Autor:
Shujin Wang, Dietbert Neumann, B. Daan Westenbrink, Francesco Schianchi, Li-Yen Wong, Aomin Sun, Agnieszka Strzelecka, Jan F. C. Glatz, Joost J. F. P. Luiken, Miranda Nabben
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 12909
International Journal of Molecular Sciences, 23(21):12909. MDPI AG
International journal of molecular sciences, 23(21):12909. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, 23(21):12909. MDPI AG
International journal of molecular sciences, 23(21):12909. Multidisciplinary Digital Publishing Institute (MDPI)
The heart is metabolically flexible. Under physiological conditions, it mainly uses lipids and glucose as energy substrates. In uncontrolled diabetes, the heart switches towards predominant lipid utilization, which over time is detrimental to cardiac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271271f426d3b4ebb25cd7ea28570770
Autor:
Jacovetti, C., Regazzi, R.
Publikováno v:
International journal of molecular sciences, vol. 23, no. 4, pp. 2096
The functional maturation of insulin-secreting β-cells is initiated before birth and is completed in early postnatal life. This process has a critical impact on the acquisition of an adequate functional β-cell mass and on the capacity to meet and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::83189b0e0b8822d3a1b959e537672851
https://serval.unil.ch/resource/serval:BIB_1B32BE187F04.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_1B32BE187F04.P001/REF.pdf
Autor:
Claudiane Guay, Adriana Rodriguez-Trejo, Cécile Jacovetti, Romano Regazzi, Kejing Wu, Mustafa Bilal Bayazit, Flora Brozzi
Publikováno v:
Comprehensive Physiology
Comprehensive Physiology, vol. 10, no. 3, pp. 893-932
Comprehensive Physiology, vol. 10, no. 3, pp. 893-932
The discovery that most mammalian genome sequences are transcribed to ribonucleic acids (RNA) has revolutionized our understanding of the mechanisms governing key cellular processes and of the causes of human diseases, including diabetes mellitus. Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d824b6d962f9faa744d9b48bed4b79
https://pubmed.ncbi.nlm.nih.gov/32941685
https://pubmed.ncbi.nlm.nih.gov/32941685
Autor:
Pauchet, A., Schwotzer, N., Lamine, F., Perrottet, N., Zanchi, A., Golshayan, D., Wojtusciszyn, A.
Publikováno v:
Revue medicale suisse, vol. 16, no. 697, pp. 1200-1205
Post-transplantation diabetes (PTDM) exposes to increased morbidity (cardiovascular or infectious complications, early graft dysfunction) and to a risk of premature death. Recognition of risk factors is essential for early and individualized care. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::7a0667a64648bf69c416ff3a0f1bd658
https://serval.unil.ch/notice/serval:BIB_77E6105192BB
https://serval.unil.ch/notice/serval:BIB_77E6105192BB
Autor:
Olle Korsgren, Raffaella Melzi, Marie Karlsson, Valery Gmyr, Julie Kerr-Conte, Lorenzo Piemonti, Vanessa Lavallard, Rita Nano, Alessia Mercalli, François Pattou, Domenico Bosco, Thierry Berney
Publikováno v:
Diabetes, Vol. 68, No 8 (2019) pp. 1541-1543
Diabetes
Diabetes
In December 2018, Diabetes and Diabetologia began requiring authors of papers reporting data obtained from studies on human islets to report critical characteristics of the human islets used for research. The islet community was asked to provide feed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef58b1bab02302430dfbce3f032411e8
https://doi.org/10.2337/db19-0367
https://doi.org/10.2337/db19-0367
Autor:
Josefa Donoso, Carlos Andrés Maya-Aguirre, Joaquín Ortega-Castro, Bartolomé Vilanova, Laura Mariño, Juan Frau, Kris Pauwels, Miquel Adrover
Publikováno v:
ACS Chemical Biology. 12:1152-1162
Glycation occurs in vivo as a result of the nonenzymatic reaction of carbohydrates (and/or their autoxidation products) with proteins, DNA, or lipids. Protein glycation causes loss-of-function and, consequently, the development of diabetic-related di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894a302a94604bd416bd0af6843fb9a0
https://doi.org/10.1021/acschembio.6b01103
https://doi.org/10.1021/acschembio.6b01103
Autor:
Simranjeet Kaur, Thomas Mandrup-Poulsen, Peter de Hemmer Horskjær, Christine Bruun, Joachim Størling, Flemming Pociot, Tina Fløyel, Anna L. Vestergaard, Romano Regazzi, Claus Heiner Bang-Berthelsen, Lukas Adrian Berchtold, Jonathan Lucien Stahl, Lisa Christen, Farzaneh Taheri Sotudeh, Klaus Stensgaard Frederiksen, Frida Greek Kofod
Publikováno v:
Vestergaard, A L, Bang-Berthelsen, C H, Floyel, T, Stahl, J L, Christen, L, Sotudeh, F T, Horskjaer, P D H, Frederiksen, K S, Kofod, F G, Bruun, C, Berchtold, L A, Storling, J, Regazzi, R, Kaur, S, Pociot, F & Mandrup-Poulsen, T 2018, ' MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage ', PLOS ONE, vol. 13, no. 9, e0203713, pp. 1-22 . https://doi.org/10.1371/journal.pone.0203713
PloS one, vol. 13, no. 9, pp. e0203713
PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0203713 (2018)
PloS one, vol. 13, no. 9, pp. e0203713
PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0203713 (2018)
Inflammatory β-cell failure contributes to type 1 and type 2 diabetes pathogenesis. Pro-inflammatory cytokines cause β-cell dysfunction and apoptosis, and lysine deacetylase inhibitors (KDACi) prevent β-cell failure in vitro and in vivo, in part b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb30b397012919ce28ea03bcc811726
https://curis.ku.dk/ws/files/210015667/journal.pone.0203713.pdf
https://curis.ku.dk/ws/files/210015667/journal.pone.0203713.pdf
Autor:
Laurent Vinet, Alvin C. Powers, Mohammad Sib Ansari, Pedro Luis Herrera, Chunhua Dai, Joseph A. Henske, Aramandla Radhika, Daniel Skovronsky, Ronald M. Baldwin, Hank F. Kung, Franz Hefti, Todd E. Peterson, Paolo Meda, Smaragda Lamprianou, John Virostko
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences, Vol. 108, No 51 (2011) pp. 20719-24
Proceedings of the National Academy of Sciences; Vol 108
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences, Vol. 108, No 51 (2011) pp. 20719-24
Proceedings of the National Academy of Sciences; Vol 108
We combined multimodal imaging (bioluminescence, X-ray computed tomography, and PET), tomographic reconstruction of bioluminescent sources, and two unique, complementary models to evaluate three previously synthesized PET radiotracers thought to targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87fe66256a5af2db366ed7d21640eb8f
https://doi.org/10.1073/pnas.1109480108
https://doi.org/10.1073/pnas.1109480108
Autor:
Paolo Meda, Anne Charollais, Philippe Klee, Dorothée Caille, Jacques-Antoine Haefliger, Smaragda Lamprianou, Rossella Sarro, Manon Cederroth
Publikováno v:
Pediatric Research; Vol 70
Pediatric Research, Vol. 70, No 2 (2011) pp. 142-7
Pediatric research
Pediatric Research
Pediatric Research, Vol. 70, No 2 (2011) pp. 142-7
Pediatric research
Pediatric Research
Diabetes develops when the insulin needs of peripheral cells exceed the availability or action of the hormone. This situation results from the death of most beta-cells in type 1 diabetes, and from an inability of the beta-cell mass to adapt to increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eec4cf7b3163d97ce59a4e621342825
https://doi.org/10.1203/pdr.0b013e318220f106
https://doi.org/10.1203/pdr.0b013e318220f106