Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Dia C. Beachboard"'
Autor:
Elise R. Huffman, Jared X. Franges, Jayden M. Doster, Alexis R. Armstrong, Yara S. Batista, Cameron M. Harrison, Jon D. Brooks, Morgan N. Thomas, Butler Student Virology Group, Sakshi Tomar, Christopher C. Stobart, Dia C. Beachboard
Publikováno v:
COVID, Vol 4, Iss 2, Pp 208-220 (2024)
The recent emergence of SARS-CoV-2 in 2019 has highlighted the necessity of antiviral therapeutics for current and future emerging coronaviruses. Recently, the traditional herbal medicines baicalein, baicalin, and andrographolide have shown inhibitio
Externí odkaz:
https://doaj.org/article/146b0aa339b84d43b95fedafe07093d6
Autor:
Andrew T. Jacob, Benjamin M. Ziegler, Stefania M. Farha, Lyla R. Vivian, Cora A. Zilinski, Alexis R. Armstrong, Andrew J. Burdette, Dia C. Beachboard, Christopher C. Stobart
Publikováno v:
Biology, Vol 12, Iss 11, p 1413 (2023)
Sin Nombre virus (SNV) is an emerging virus that was first discovered in the Four Corners region of the United States in 1993. The virus causes a disease known as Hantavirus Pulmonary Syndrome (HPS), sometimes called Hantavirus Cardiopulmonary Syndro
Externí odkaz:
https://doaj.org/article/316851d2e2e04c4ab27ef5fb6b759b2f
Autor:
Cameron M. Harrison, Jayden M. Doster, Emily H. Landwehr, Nidhi P. Kumar, Ethan J. White, Dia C. Beachboard, Christopher C. Stobart
Publikováno v:
Microorganisms, Vol 11, Iss 2, p 445 (2023)
Approximately 15–30% of all cases of the common cold are due to human coronavirus infections. More recently, the emergence of the more severe respiratory coronaviruses, SARS-CoV and MERS-CoV, have highlighted the increased pathogenic potential of e
Externí odkaz:
https://doaj.org/article/a1456a631eab4ddc8b169108fb5169e1
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The RNA binding protein RIG-I is a key initiator of the antiviral innate immune response. The signaling that mediates the antiviral response downstream of RIG-I is transduced through the adaptor protein MAVS and results in the induction of type I and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6903eaea8fdae3c241825e2e1d7b7cb8
https://doi.org/10.1073/pnas.2119531119
https://doi.org/10.1073/pnas.2119531119
Autor:
Dia C. Beachboard, Daltry L. Snider, Madhuvanthi Vijayan, Michael J. McFadden, Sydney Stanley, Stacy M. Horner, Dillon J. Fernando, Graham D. Williams, Moonhee Park
Publikováno v:
J Biol Chem
Innate immune detection of viral nucleic acids during viral infection activates a signaling cascade that induces type I and type III IFNs as well as other cytokines, to generate an antiviral response. This signaling is initiated by pattern recognitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed9d49af40f9ab027ddd8c1e1d17836
https://doi.org/10.1074/jbc.ra119.007917
https://doi.org/10.1074/jbc.ra119.007917
Publikováno v:
Journal of General Virology
Coronavirus protease nsp5 (M pro , 3CL pro ) remains a primary target for coronavirus therapeutics due to its indispensable and conserved role in the proteolytic processing of the viral replicase polyproteins. In this review, we discuss the diversity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c3fa08ee1473f6e4df95d96aed6c1c
https://doi.org/10.1099/jgv.0.001558
https://doi.org/10.1099/jgv.0.001558
Publikováno v:
The Journal of General Virology
Coronavirus protease nsp5 (Mpro, 3CLpro) remains a primary target for coronavirus therapeutics due to its indispensable and conserved role in the proteolytic processing of the viral replicase polyproteins. In this review, we discuss the diversity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::597f4213f0bd4a1c301f91b15ab03987
https://pubmed.ncbi.nlm.nih.gov/33507143
https://pubmed.ncbi.nlm.nih.gov/33507143
Autor:
Heather R Williamson, Mark E Benbow, Khoa D Nguyen, Dia C Beachboard, Ryan K Kimbirauskas, Mollie D McIntosh, Charles Quaye, Edwin O Ampadu, Daniel Boakye, Richard W Merritt, Pamela L C Small
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 3, p e205 (2008)
Mycobacterium ulcerans, the causative agent of Buruli ulcer, is an emerging environmental bacterium in Australia and West Africa. The primary risk factor associated with Buruli ulcer is proximity to slow moving water. Environmental constraints for di
Externí odkaz:
https://doaj.org/article/59ef0aeec673489da2a2562c8136f245
Autor:
Moonhee Park, Graham D. Williams, Dillon J. Fernando, Madhuvanthi Vijayan, Stacy M. Horner, Dia C. Beachboard
Nucleic acid-based antiviral innate immunity activates a signaling cascade that induces type I and type III interferons (IFNs), and other cytokines. This signaling, which is highly regulated, is initiated by pattern recognition receptors, such as RIG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d04792d81693b3313ce386cb4f6e67
https://doi.org/10.1101/542050
https://doi.org/10.1101/542050
Autor:
Dia C. Beachboard, Stacy M. Horner
Publikováno v:
Current Opinion in Microbiology
Upon infection, both DNA and RNA viruses can be sensed by pattern recognition receptors (PRRs) in the cytoplasm or the nucleus to activate antiviral innate immunity. Sensing of viral products leads to the activation of a signaling cascade that ultima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19972edab5c6da98bb1f01ad874d59f1