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Breast Multiparametric MRI for Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer: The BMMR2 Challenge.

Autor: Li W; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Partridge SC; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Newitt DC; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Steingrimsson J; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Marques HS; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Bolan PJ; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Hirano M; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Bearce BA; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Kalpathy-Cramer J; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Boss MA; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Teng X; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Zhang J; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Cai J; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Kontos D; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Cohen EA; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Mankowski WC; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Liu M; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Ha R; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Pellicer-Valero OJ; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Maier-Hein K; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Rabinovici-Cohen S; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Tlusty T; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Ozery-Flato M; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Parekh VS; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Jacobs MA; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Yan R; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Sung K; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Kazerouni AS; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., DiCarlo JC; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Yankeelov TE; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Chenevert TL; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.)., Hylton NM; From the Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, Calif (W.L., D.C.N., N.M.H.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA 98109 (S.C.P., M.H., A.S.K.); Center for Statistical Sciences, Brown University, Providence, RI (J.S., H.S.M.); Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minn (P.J.B.); Athinoula A. Martinos Center for Biomedical Imaging, Harvard University, Charlestown, Mass (B.A.B., J.K.C.); Center for Research and Innovation, American College of Radiology, Philadelphia, Pa (M.A.B.); Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (X.T., J.Z., J.C.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.K., E.A.C., W.C.M.); Department of Radiology, Columbia University Medical Center, New York, NY (M.L., R.H.); Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany (O.J.P.V., K.M.H.); Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.M.H.); IBM Research-Israel, Haifa University Campus, Mount Carmel, Haifa, Israel (S.R.C., T.T., M.O.F.); University of Maryland Medical Intelligent Imaging (UM2ii) Center and Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Md (V.S.P.); The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Md (V.S.P., M.A.J.); Department of Diagnostic and Interventional Imaging, UT Health at Houston, Houston, Tex (M.A.J.); Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Calif (R.Y., K.S.); Department of Bioengineering, Henry Samueli School of Engineering, University of California, Los Angeles, Calif (R.Y., K.S.); Livestrong Cancer Institutes (J.C.D., T.E.Y.), Departments of Biomedical Engineering, Diagnostic Medicine, and Oncology (T.E.Y.), and The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (J.C.D., T.E.Y.); Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex (T.E.Y.); and Department of Radiology, University of Michigan, Ann Arbor, Mich (T.L.C.).

Publikováno v: Radiology. Imaging cancer [Radiol Imaging Cancer] 2024 Jan; Vol. 6 (1), pp. e230033.

Analysis of simplicial complexes to determine when to sample for quantitative DCE MRI of the breast.

Autor: DiCarlo JC; The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Texas, USA.; Livestrong Cancer Institutes, The University of Texas at Austin, Austin, Texas, USA., Jarrett AM; The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Texas, USA., Kazerouni AS; Department of Radiology, University of Washington, Seattle, Washington, USA., Virostko J; The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Texas, USA.; Livestrong Cancer Institutes, The University of Texas at Austin, Austin, Texas, USA.; Department of Diagnostic Medicine, The University of Texas at Austin, Austin, Texas, USA., Sorace A; Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.; Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, Alabama, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA., Slavkova KP; Department of Physics, The University of Texas at Austin, Austin, Texas, USA., Woodard S; Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Avery S; Department of Diagnostic Medicine, The University of Texas at Austin, Austin, Texas, USA.; Austin Radiological Association, Austin, Texas, USA., Patt D; Texas Oncology, Austin, Texas, USA., Goodgame B; Department of Oncology, University of Texas at Austin, Austin, Texas, USA.; Department of Internal Medicine, University of Texas at Austin, Austin, Texas, USA.; Ascension Seton Medical Center, Austin, Texas, USA., Yankeelov TE; The Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Texas, USA.; Livestrong Cancer Institutes, The University of Texas at Austin, Austin, Texas, USA.; Department of Diagnostic Medicine, The University of Texas at Austin, Austin, Texas, USA.; Department of Oncology, University of Texas at Austin, Austin, Texas, USA.; Department of Biomedical Engineering, The University of Texas at Austin, Austin, Texas, USA.; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Publikováno v: Magnetic resonance in medicine [Magn Reson Med] 2023 Mar; Vol. 89 (3), pp. 1134-1150. Date of Electronic Publication: 2022 Nov 02.

Quantitative multiparametric MRI predicts response to neoadjuvant therapy in the community setting.

Autor: Virostko J; Department of Diagnostic Medicine, University of Texas at Austin, Austin, TX, 78712, USA.; Livestrong Cancer Institutes, University of Texas at Austin, Austin, TX, USA.; Department of Oncology, University of Texas at Austin, Austin, TX, USA.; Oden Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, USA., Sorace AG; Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Slavkova KP; Department of Physics, University of Texas at Austin, Austin, TX, USA., Kazerouni AS; Department of Radiology, University of Washington, Seattle, WA, USA., Jarrett AM; Oden Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, USA., DiCarlo JC; Livestrong Cancer Institutes, University of Texas at Austin, Austin, TX, USA.; Oden Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, USA., Woodard S; Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA., Avery S; Austin Radiological Association, Austin, TX, USA., Goodgame B; Dell Seton Medical Center at the University of Texas, Austin, USA., Patt D; Texas Oncology, Austin, TX, USA., Yankeelov TE; Department of Diagnostic Medicine, University of Texas at Austin, Austin, TX, 78712, USA. thomas.yankeelov@utexas.edu.; Livestrong Cancer Institutes, University of Texas at Austin, Austin, TX, USA. thomas.yankeelov@utexas.edu.; Department of Oncology, University of Texas at Austin, Austin, TX, USA. thomas.yankeelov@utexas.edu.; Oden Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, USA. thomas.yankeelov@utexas.edu.; Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA. thomas.yankeelov@utexas.edu.; Department of Imaging Physics, MD Anderson Cancer Center, Houston, TX, USA. thomas.yankeelov@utexas.edu.

Publikováno v: Breast cancer research : BCR [Breast Cancer Res] 2021 Nov 27; Vol. 23 (1), pp. 110. Date of Electronic Publication: 2021 Nov 27.

Characterizing Errors in Pharmacokinetic Parameters from Analyzing Quantitative Abbreviated DCE-MRI Data in Breast Cancer.

Autor: Slavkova KP; Department of Physics, The University of Texas at Austin, Austin, TX 78712, USA., DiCarlo JC; Livestrong Cancer Institutes, The University of Texas at Austin, Austin, TX 78712, USA.; Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, TX 78712, USA., Kazerouni AS; Department of Radiology, The University of Washington, Seattle, WA 98195, USA., Virostko J; Livestrong Cancer Institutes, The University of Texas at Austin, Austin, TX 78712, USA.; Department of Diagnostic Medicine, The University of Texas at Austin, Austin, TX 78712, USA., Sorace AG; Department of Radiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.; Department of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.; O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL 35294, USA., Patt D; Texas Oncology, Austin, TX 78731, USA., Goodgame B; Seton Hospital, Austin, TX 78712, USA.; Department of Internal Medicine, The University of Texas at Austin, Austin, TX 78712, USA., Yankeelov TE; Livestrong Cancer Institutes, The University of Texas at Austin, Austin, TX 78712, USA.; Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, TX 78712, USA.; Department of Diagnostic Medicine, The University of Texas at Austin, Austin, TX 78712, USA.; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center Houston, Houston, TX 77030, USA.; Department of Oncology, The University of Texas at Austin, Austin, TX 78712, USA.; Department of Biomedical Engineering, The University of Texas at Austin, 107 W Dean Keeton Street, Stop C0800, Austin, TX 787812, USA.

Publikováno v: Tomography (Ann Arbor, Mich.) [Tomography] 2021 Jun 23; Vol. 7 (3), pp. 253-267. Date of Electronic Publication: 2021 Jun 23.