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Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Poly (ADP-ribose) polymerase 1 (PARP1) is a key DNA damage sensor that is recruited to damaged sites after DNA strand breaks to initiate DNA repair. This is achieved by catalyzing attachment of ADP-ribose moieties, which are donated from NAD+, on the
Externí odkaz:
https://doaj.org/article/de6e378545e14978ac8ae0675bbb22a6