Zobrazeno 1 - 10
of 306
pro vyhledávání: '"Di Zhong"'
Autor:
Shuai Yang, Xudong Li, Jinhong Yan, Fangchao Jiang, Xuehui Fan, Jing Jin, Weihua Zhang, Di Zhong, Guozhong Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract In the current study, we aimed to investigate whether disulfiram (DSF) exerts a neuroprotective role in cerebral ischemiareperfusion (CI-RI) injury by modulating ferredoxin 1 (FDX1) to regulate copper ion (Cu) levels and inhibiting inflammat
Externí odkaz:
https://doaj.org/article/c60db0de0f02496784617aff08477d7b
Autor:
Wei Fan, Hongping Chen, Meng Li, Xuehui Fan, Fangchao Jiang, Chen Xu, Yingju Wang, Wan Wei, Jihe Song, Di Zhong, Guozhong Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Arterial occlusion-induced ischemic stroke (IS) is a highly frequent stroke subtype. Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that modulates antioxidant genes. Its role in IS is still unelucidated. The cur
Externí odkaz:
https://doaj.org/article/71728a86a3884b22994ec5805c5c4e61
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
AbstractInterferon-beta (IFN-[Formula: see text]) is one of the classical drugs for immunomodulatory therapy in relapsing-remitting multiple sclerosis (RRMS) patients, but the drug responsiveness of different patients varies. Currently, there is no v
Externí odkaz:
https://doaj.org/article/1e3a3be9ffe941da87f901e9360757ca
Autor:
Meng Li, Jihe Song, Pengqi Yin, Hongping Chen, Yingju Wang, Chen Xu, Fangchao Jiang, Haining Wang, Baichao Han, Xinshu Du, Wei Wang, Guozhong Li, Di Zhong
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Guillain–Barré syndrome (GBS) is an autoimmune disorder wherein the composition and gene expression patterns of peripheral blood immune cells change significantly. It is triggered by antigens with similar epitopes to Schwann cells that st
Externí odkaz:
https://doaj.org/article/fb4689abcd564355952bfddd4f2e5d06
Autor:
Huhu Zhang, Zhe Zhang, Tingting Guo, Guang Chen, Guoxiang Liu, Qinghang Song, Guichun Li, Fenghua Xu, Xiaolei Dong, Fanghao Yang, Can Cao, Di Zhong, Shuang Li, Ya Li, Mengjun Wang, Bing Li, Lina Yang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The annexin A (ANXA) protein family is a well-known tissue-specific multigene family that encodes Ca2+ phospholipid-binding proteins. A considerable amount of literature is available on the abnormal expression of ANXA proteins in various malignant di
Externí odkaz:
https://doaj.org/article/77213a6f40ec4cbead3da3409da6cfc5
Autor:
Xuehui Fan, Hongping Chen, Fangchao Jiang, Chen Xu, Yingju Wang, Haining Wang, Meng Li, Wan Wei, Jihe Song, Di Zhong, Guozhong Li
Publikováno v:
Frontiers in Neurology, Vol 13 (2023)
BackgroundImmune infiltration plays an important role in the course of ischemic stroke (IS) progression. Cuproptosis is a newly discovered form of programmed cell death. To date, no studies on the mechanisms by which cuproptosis-related genes regulat
Externí odkaz:
https://doaj.org/article/7d55f820636547ebaeeec77e6875dab2
Publikováno v:
Medicina, Vol 59, Iss 7, p 1267 (2023)
Respiratory muscle paralysis is known as a very common complication of Guillain–Barré syndrome (GBS). However, most research has focused on its later stages rather than its earlier stages, including the prognosis of patients with this condition, o
Externí odkaz:
https://doaj.org/article/667c740c66ad4bb1b48a53a386ec2209
Publikováno v:
Cellular & Molecular Biology Letters, Vol 26, Iss 1, Pp 1-12 (2021)
Abstract Developmental endothelial locus-1 (Del-1) is a secretory, multifunctional domain protein. It can bind to integrins and phosphatidylserine. As a local tissue signal, it plays a regulatory role in the cancer microenvironment and inflammation.
Externí odkaz:
https://doaj.org/article/f0e554074838401aa9db80b24cefaadf
Autor:
Xuehui Fan, Hongping Chen, Chen Xu, Yingju Wang, Pengqi Yin, Meng Li, Zhanbin Tang, Fangchao Jiang, Wan Wei, Jihe Song, Guozhong Li, Di Zhong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Ischemic stroke is the most common stroke incident. Sphingosine-1-phosphate (S1P) receptor 3 (S1PR3) is a member of the downstream G protein-coupled receptor family of S1P. The effect of S1PR3 on ischemic stroke remains elusive.Methods: W
Externí odkaz:
https://doaj.org/article/c2b0bc61f3744c2d85a4ba888a221579
Autor:
Xuehui Fan, Hongping Chen, Chen Xu, Yingju Wang, Pengqi Yin, Meng Li, Zhanbin Tang, Fangchao Jiang, Wan Wei, Jihe Song, Guozhong Li, Di Zhong
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
BackgroundIschemic stroke (IS) is a common disease endangering human life and health. Cerebral ischemia triggers a series of complex harmful events, including excitotoxicity, inflammation and cell death, as well as increased nitric oxide production t
Externí odkaz:
https://doaj.org/article/d890935a2ab448b48c3390ebe25c7f2c