Development of an intraventricular adeno-associated virus-based labeling strategy for glioblastoma cells nested in the subventricular zone.

Autor: Lombard A; Neurosurgery Department, CHR Citadelle, Liège, Belgium.; Laboratory of Nervous System Diseases and Therapy, GIGA Neuroscience, University of Liège, Liège, Belgium., Isci D; Laboratory of Nervous System Diseases and Therapy, GIGA Neuroscience, University of Liège, Liège, Belgium., Reuter G; Neurosurgery Department, University Hospital, Liège, Belgium., Di Valentin E; GIGA Viral Vectors Platform, University of Liège, Belgium., Hego A; GIGA Cell Imaging Platform, University of Liège, Liège, Belgium., Martin D; Neurosurgery Department, University Hospital, Liège, Belgium., Rogister B; Neurology Department, University Hospital, Liège, Belgium.; Laboratory of Nervous System Diseases and Therapy, GIGA Neuroscience, University of Liège, Liège, Belgium., Neirinckx V; Laboratory of Nervous System Diseases and Therapy, GIGA Neuroscience, University of Liège, Liège, Belgium.

Publikováno v: Neuro-oncology advances [Neurooncol Adv] 2024 Sep 28; Vol. 6 (1), pp. vdae161. Date of Electronic Publication: 2024 Sep 28 (Print Publication: 2024).

Mapping the human genetic architecture of COVID-19

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Albertos, R, Perez-Tur, J, Li, R, Folkersen, L, Moltke, I, Koelling, N, Teumer, A, Kousathanas, A, Utrilla, A, Verdugo, RA, Zarate, R, Medina-Gomez, C, Gomez-Cabrero, D, Carnero-Montoro, E, Cadilla, CL, Moreno-Estrada, A, Garmendia, A, Moya, L, Sedaghati-Khayat, B, Boua, PR, Fave, M-J, Francioli, L, Lemacon, A, Migeotte, I, Patel, S, Varnai, R, Szentpeteri, JL, Sipeky, C, Colombo, F, von Hohenstaufen, K, Lio, P, Vallerga, C, Wang, Q, Tanigawa, Y, Im, H, Han, C, Song, H, Lim, J, Lee, Y, Kim, S, Im, S, Atanasovska, B, Ahmad, HF, Boer, C, Jansen, P, Franke, L, Kaja, E, Pasko, D, Kennis-Szilagyi, I, Kornilov, SA, Prijatelj, V, Prokic, I, Sivanadhan, I, Perumal, S, Esmaeeli, S, Pearson, NM, Auton, A, Shelton, JF, Shastri, AJ, Filshtein-Sonmez, T, Coker, D, Symons, A, Esparza-Gordillo, J, Aslibekyan, S, O'Connell, J, Ye, C, Weldon, CH, Perera, M, O'Leary, K, Tuck, M, O'Brien, T, Meltzer, D, O'Donnell, P, Nutescu, E, Yang, G, Alarcon, C, Herrmann, S, Mazurek, S, Banagan, J, Hamidi, Z, 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Publikováno v: NATURE
Initiative, COVID H G & Dark, P 2021, ' Mapping the human genetic architecture of COVID-19. ', Nature, vol. 600, no. 7889, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
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COVID-19 Host Genetics Initiative 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature, vol. 600, no. 7889, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature, 2021, 600 (7889), pp.472-477. ⟨10.1038/s41586-021-03767-x⟩
Nature, Vol. 600, no. ²7889, p. 472-477 (2021)
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Nature, vol. 600, no. 7889, pp. 472-477
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Niemi, M E K, Karjalainen, J, Liao, R G, Neale, B M, Daly, M, Ganna, A, Pathak, G A, Andrews, S J, Kanai, M, Veerapen, K, Fernandez-Cadenas, I, Schulte, E C, Striano, P, Marttila, M, Minica, C, Marouli, E, Karim, M A, Wendt, F R, Savage, J, Sloofman, L, Butler-Laporte, G, Kim, H-N, Kanoni, S, Okada, Y, Byun, J, Han, Y, Uddin, M J, Smith, G D, Willer, C J, Buxbaum, J D, Karjalainen, J, Mehtonen, J, Folkersen, L, Moltke, I, Hinney, A, Wang, C, Ellinghaus, D, Brunak, S, Castro, P, Guindo-Martinez, M, Lee, J Y, Loos, R J F, Zhao, J H, Sun, Y V, Wang, B, Parker, R, Garcia, S M, Smith, O, Davis, C, COVID-19 Host Genetics Initiative, 23andMe COVID-19 Team, Norwegian SARS-CoV-2 Study Grp, Humanitas COVID-19 Task Force, Humanitas Gavazzeni COVID-19 Task, FHoGID, RegCOVID, P-PredictUs, SeroCOVID, CRiPSI, Genes & Hlth Res Team & UCLA Hlth ATLAS Data Mart Working 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature, vol. 600, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature (Lond.) 600 (2021): 472–+. doi:10.1038/s41586-021-03767-x
info:cnr-pdr/source/autori:Mari E. K. Niemi; Juha Karjalainen; Rachel G. Liao; Benjamin M. Neale; Mark Daly; Andrea Ganna; COVID-19 Host Genetics Initiative and the GEN-COVID Multicenter Study (including Stella, Alessandra and Biscarini, Filippo)/titolo:Mapping the human genetic architecture of COVID-19/doi:10.1038%2Fs41586-021-03767-x/rivista:Nature (Lond.)/anno:2021/pagina_da:472/pagina_a:+/intervallo_pagine:472–+/volume:600
Ganna, A & Davey Smith, G 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature . https://doi.org/10.1038/s41586-021-03767-x
Nature 600, 472-477 (2021)
Baillie, J K, Wilson, J F, Bulteel, N, Hayward, C, Klaric, L, Porteous, D J, Russell, C D, Tenesa, A, Norman, L & Scott-Brown, J & Swann, O 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature . https://doi.org/10.1038/s41586-021-03767-x

Niemi, Mari E. K. et al. 39 páginas, figuras y tablas. Contiene material suplementario.
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974d087615705cffb4d0d7bdc6394ffc
https://eprints.soton.ac.uk/456122/

Specific DMPK -promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells.

Autor: Porquet F; Laboratory of Molecular and Cellular Epigenetics, GIGA-Cancer, ULiège, 4000 Liège, Belgium.; Laboratory of Neurophysiology, GIGA-Neurosciences, ULiège, 4000 Liège, Belgium.; Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, 75013 Paris, France., Weidong L; Laboratory of Molecular and Cellular Epigenetics, GIGA-Cancer, ULiège, 4000 Liège, Belgium., Jehasse K; Laboratory of Neurophysiology, GIGA-Neurosciences, ULiège, 4000 Liège, Belgium., Gazon H; Laboratory of Molecular and Cellular Epigenetics, GIGA-Cancer, ULiège, 4000 Liège, Belgium., Kondili M; Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, 75013 Paris, France., Blacher S; Laboratory of Biology of Tumor and Development, GIGA-Cancer, ULiège, 4000 Liège, Belgium., Massotte L; Laboratory of Neurophysiology, GIGA-Neurosciences, ULiège, 4000 Liège, Belgium., Di Valentin E; Viral Vector Platform, GIGA, ULiège, 4000 Liège, Belgium., Furling D; Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, 75013 Paris, France., Gillet NA; Namur Research Institute for Life Sciences (NARILIS), Integrated Veterinary Research Unit (URVI), University of Namur, 5000 Namur, Belgium., Klein AF; Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, 75013 Paris, France., Seutin V; Laboratory of Neurophysiology, GIGA-Neurosciences, ULiège, 4000 Liège, Belgium., Willems L; Laboratory of Molecular and Cellular Epigenetics, GIGA-Cancer, ULiège, 4000 Liège, Belgium.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2023 May 13; Vol. 32, pp. 857-871. Date of Electronic Publication: 2023 May 13 (Print Publication: 2023).

PI3Kδ activity controls plasticity and discriminates between EMT and stemness based on distinct TGFβ signaling.

Autor: Agnetti J; INSERM, Unité 1193, Villejuif, F-94800, France.; Université Paris-Saclay, UMR-S 1193, Villejuif, F-94800, France., Bou Malham V; INSERM, Unité 1193, Villejuif, F-94800, France.; Université Paris-Saclay, UMR-S 1193, Villejuif, F-94800, France., Desterke C; Université Paris-Saclay, UFR Médecine- INSERM UA9, Villejuif, France., Benzoubir N; INSERM, Unité 1193, Villejuif, F-94800, France.; Université Paris-Saclay, UMR-S 1193, Villejuif, F-94800, France., Peng J; INSERM, Unité 1193, Villejuif, F-94800, France.; Université Paris-Saclay, UMR-S 1193, Villejuif, F-94800, France., Jacques S; Laboratory of animal Genomics, GIGA-Medical Genomics, GIGA-institute, Université de Liège, Liège, Belgium., Rahmouni S; Laboratory of animal Genomics, GIGA-Medical Genomics, GIGA-institute, Université de Liège, Liège, Belgium., Di Valentin E; Plateforme des vecteurs viraux, GIGA B34, GIGA-institute, Université de Liège, Liège, Belgium., Tan TZ; Cancer Science Institute of Singapore National University of Singapore, Center for Translational Medicine, 14 Medical Drive, #12-01, 117599, Singapore, Singapore., Samuel D; INSERM, Unité 1193, Villejuif, F-94800, France.; Université Paris-Saclay, UMR-S 1193, Villejuif, F-94800, France.; AP-HP Hôpital Paul Brousse, Centre Hepato-Biliaire, F-94800, Villejuif, France., Thiery JP; Guangzhou Laboratory, International biological Island Guangzhou, 510005, Guangzhou, China., Gassama-Diagne A; INSERM, Unité 1193, Villejuif, F-94800, France. ama.gassama@inserm.fr.; Université Paris-Saclay, UMR-S 1193, Villejuif, F-94800, France. ama.gassama@inserm.fr.

Publikováno v: Communications biology [Commun Biol] 2022 Jul 25; Vol. 5 (1), pp. 740. Date of Electronic Publication: 2022 Jul 25.

Novel Loss of Function Variant in BCKDK Causes a Treatable Developmental and Epileptic Encephalopathy.

Autor: Boemer F; Biochemical Genetics Laboratory, Department of Human Genetics, CHU of Liege, University of Liege, 4000 Liege, Belgium., Josse C; Department of Medical Oncology, CHU of Liege, University of Liege, 4000 Liege, Belgium.; Laboratory of Human Genetics, Department of Biomedical and Preclinical Sciences, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Recherche (GIGA-R), University of Liege, 4000 Liege, Belgium., Luis G; Biochemical Genetics Laboratory, Department of Human Genetics, CHU of Liege, University of Liege, 4000 Liege, Belgium., Di Valentin E; Viral Vector Platform, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Recherche (GIGA-R), University of Liege, 4000 Liege, Belgium., Thiry J; Department of Medical Oncology, CHU of Liege, University of Liege, 4000 Liege, Belgium., Cello C; Biochemical Genetics Laboratory, Department of Human Genetics, CHU of Liege, University of Liege, 4000 Liege, Belgium., Caberg JH; Molecular Genetics Laboratory, Department of Human Genetics, CHU of Liege, University of Liege, 4000 Liege, Belgium., Dadoumont C; Department of Pediatrics, CHC MontLégia, 4000 Liege, Belgium., Harvengt J; Center of Genetics, Department of Human Genetics, CHU of Liege, University of Liege, 4000 Liege, Belgium., Lumaka A; Laboratory of Human Genetics, Department of Biomedical and Preclinical Sciences, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Recherche (GIGA-R), University of Liege, 4000 Liege, Belgium., Bours V; Center of Genetics, Department of Human Genetics, CHU of Liege, University of Liege, 4000 Liege, Belgium., Debray FG; Metabolic Unit, Department of Human Genetics, CHU of Liege, University of Liege, 4000 Liege, Belgium.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Feb 18; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 18.