Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen

Autor: SALEM, R. M., TODD, J. N., SANDHOLM, N., COLE, J. B., CHEN, W. M., Andrews, D., PEZZOLESI, M. G., MCKEIGUE, P. M., HIRAKI, L. T., Qiu, C., Nair, V., DI LIAO, C., Cao, J. J., VALO, E., ONENGUT-GUMUSCU, S., SMILES, A. M., MCGURNAGHAN, S. J., HAUKKA, J. K., HARJUTSALO, V., BRENNAN, E. P., VAN ZUYDAM, N., AHLQVIST, E., Doyle, R., AHLUWALIA, T. S., LAJER, M., HUGHES, M. F., Park, J., SKUPIEN, J., SPILIOPOULOU, A., Liu, A., Menon, R., BOUSTANY-KARI, C. M., KANG, H. M., NELSON, R. G., Klein, R., KLEIN, B. E., Lee, K. E., Gao, X., Mauer, M., MAESTRONI, S., CARAMORI, M. L., DE BOER, I. H., MILLER, R. G., Guo, J., BORIGHT, A. P., TREGOUET, D., Gyorgy, B., SNELL-BERGEON, J. K., MAAHS, D. M., BULL, S. B., CANTY, A. J., PALMER, C. N. A., STECHEMESSER, L., PAULWEBER, B., WEITGASSER, R., SOKOLOVSKA, J., ROVITE, V., PIRAGS, V., PRAKAPIENE, E., RADZEVICIENE, L., VERKAUSKIENE, R., PANDURU, N. M., GROOP, L. C., McCarthy, M. I., GU, H. F., MOLLSTEN, A., FALHAMMAR, H., Brismar, K., Martin, F., ROSSING, P., COSTACOU, T., ZERBINI, G., Marre, M., Hadjadj, S., MCKNIGHT, A. J., FORSBLOM, C., McKay, G., GODSON, C., Maxwell, A. P., KRETZLER, M., SUSZTAK, K., COLHOUN, H. M., KROLEWSKI, A., PATERSON, A. D., GROOP, P. H., RICH, S. S., HIRSCHHORN, J. N., FLOREZ, J. C.

Publikováno v: Journal of the American Society of Nephrology
Journal of the American Society of Nephrology, American Society of Nephrology, In press, 30 (10), pp.2000-2016. ⟨10.1681/asn.2019030218⟩

BACKGROUND: Although diabetic kidney disease demonstrates both familial clustering and single nucleotide polymorphism heritability, the specific genetic factors influencing risk remain largely unknown. METHODS: To identify genetic variants predisposi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1a6014230dda30383e7df3ba9c0d680c
https://hal.archives-ouvertes.fr/hal-02898065

Determining the factors associated with health research participation.

Autor: Gucciardi E, Di Liao C, Cameron JI

Publikováno v: Journal of Ambulatory Care Management; 2010 Jul-Sep, Vol. 33 Issue 3, p272-284, 13p

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.

Autor: Salem RM; Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California., Todd JN; Division of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.; Programs in Metabolism and Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts.; Center for Genomic Medicine and., Sandholm N; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine and., Cole JB; Division of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.; Programs in Metabolism and Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts.; Center for Genomic Medicine and., Chen WM; Center for Public Health Genomics, School of Medicine, University of Virginia, Charlottesville, Virginia., Andrews D; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland., Pezzolesi MG; Division of Nephrology and Hypertension, Diabetes and Metabolism Center, University of Utah, Salt Lake City, Utah., McKeigue PM; Usher Institute of Population Health Sciences and Informatics and., Hiraki LT; The Hospital for Sick Children, Toronto, Ontario, Canada., Qiu C; Departments of Medicine and Genetics, University of Pennsylvania, Philadelphia, Pennsylvania., Nair V; Division of Nephrology, Department of Internal Medicine and., Di Liao C; The Hospital for Sick Children, Toronto, Ontario, Canada., Cao JJ; The Hospital for Sick Children, Toronto, Ontario, Canada., Valo E; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine and., Onengut-Gumuscu S; Center for Public Health Genomics, School of Medicine, University of Virginia, Charlottesville, Virginia., Smiles AM; Joslin Diabetes Center, Boston, Massachusetts., McGurnaghan SJ; Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Haukka JK; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine and., Harjutsalo V; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine and.; The Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland., Brennan EP; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland., van Zuydam N; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Ahlqvist E; Department of Genomics, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden., Doyle R; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland., Ahluwalia TS; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Lajer M; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Hughes MF; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland., Park J; Departments of Medicine and Genetics, University of Pennsylvania, Philadelphia, Pennsylvania., Skupien J; Joslin Diabetes Center, Boston, Massachusetts., Spiliopoulou A; Usher Institute of Population Health Sciences and Informatics and., Liu A; Department of Biostatistics and., Menon R; Division of Nephrology, Department of Internal Medicine and.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan., Boustany-Kari CM; Cardiometabolic Diseases Research, Boehringer Ingelheim, Ridgefield, Connecticut., Kang HM; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan., Nelson RG; Chronic Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona., Klein R; University of Wisconsin-Madison, Madison, Wisconsin., Klein BE; University of Wisconsin-Madison, Madison, Wisconsin., Lee KE; University of Wisconsin-Madison, Madison, Wisconsin., Gao X; The George Washington University, Washington, DC., Mauer M; University of Minnesota, Minneapolis, Minnesota., Maestroni S; Complications of Diabetes Unit, Division of Immunology, Transplantation and Infectious Diseases, Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milano, Italy., Caramori ML; University of Minnesota, Minneapolis, Minnesota., de Boer IH; University of Washington, Seattle, Washington., Miller RG; University of Pittsburgh Public Health, Pittsburgh, Pennsylvania., Guo J; University of Pittsburgh Public Health, Pittsburgh, Pennsylvania., Boright AP; The Hospital for Sick Children, Toronto, Ontario, Canada., Tregouet D; INSERM UMR_S 1166, Sorbonne Université, UPMC Univ Paris 06, Paris, France.; ICAN Institute for Cardiometabolism and Nutrition, Paris, France., Gyorgy B; INSERM UMR_S 1166, Sorbonne Université, UPMC Univ Paris 06, Paris, France.; ICAN Institute for Cardiometabolism and Nutrition, Paris, France., Snell-Bergeon JK; University of Colorado School of Medicine, Aurora, Colorado., Maahs DM; Department of Pediatrics-Endocrinology, Stanford University, Stanford, California., Bull SB; The Lunenfeld-Tanenbaum Research Institute, University of Toronto, Toronto, Ontario, Canada., Canty AJ; Department of Mathematics and Statistics, McMaster University, Hamilton, Ontario, Canada., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Stechemesser L; First Department of Medicine, Paracelsus Medical University, Salzburg, Austria., Paulweber B; First Department of Medicine, Paracelsus Medical University, Salzburg, Austria., Weitgasser R; First Department of Medicine, Paracelsus Medical University, Salzburg, Austria.; Department of Medicine, Diakonissen-Wehrle Hospital, Salzburg, Austria., Sokolovska J; University of Latvia, Riga, Latvia., Rovīte V; Latvian Biomedical Research and Study Centre, Riga, Latvia., Pīrāgs V; University of Latvia, Riga, Latvia.; Pauls Stradins University Hospital, Riga, Latvia., Prakapiene E; Medical Academy and., Radzeviciene L; Institute of Endocrinology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania., Verkauskiene R; Institute of Endocrinology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania., Panduru NM; Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; 2nd Clinical Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania., Groop LC; Department of Genomics, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., McCarthy MI; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK.; Genentech, 1 DNA Way, South San Francisco, California., Gu HF; Department of Clinical Science, Intervention and Technology and.; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China., Möllsten A; Division of Pediatrics, Department of Clinical Sciences, Umeå University, Umeå, Sweden., Falhammar H; Department of Molecular Medicine and Surgery, Rolf Luft Center for Diabetes Research and Endocrinology, Karolinska Institutet, Stockholm, Sweden.; Department of Endocrinology, Diabetes and Metabolism, Karolinska University Hospital, Stockholm, Sweden., Brismar K; Department of Molecular Medicine and Surgery, Rolf Luft Center for Diabetes Research and Endocrinology, Karolinska Institutet, Stockholm, Sweden.; Department of Endocrinology, Diabetes and Metabolism, Karolinska University Hospital, Stockholm, Sweden., Martin F; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland., Rossing P; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; University of Copenhagen, Copenhagen, Denmark., Costacou T; University of Pittsburgh Public Health, Pittsburgh, Pennsylvania., Zerbini G; Complications of Diabetes Unit, Division of Immunology, Transplantation and Infectious Diseases, Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milano, Italy., Marre M; Department of Diabetology, Endocrinology and Nutrition, Bichat Hospital, DHU FIRE, Assistance Publique-Hôpitaux de Paris, Paris, France.; UFR de Médecine, Paris Diderot University, Sorbonne Paris Cité, Paris, France.; INSERM UMRS 1138, Cordeliers Research Center, Paris, France.; Fondation Ophtalmologique Adolphe de Rothschild, Paris, France., Hadjadj S; Department of Endocrinology and Diabetology, Centre Hospitalier Universitaire de Poitiers, Poitiers, France.; INSERM CIC 1402, Poitiers, France.; L'institut du thorax, INSERM, CNRS, CHU Nantes, Nantes, France., McKnight AJ; Centre for Public Health, Queens University of Belfast, Northern Ireland, UK., Forsblom C; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine and.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine and., McKay G; Centre for Public Health, Queens University of Belfast, Northern Ireland, UK., Godson C; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland., Maxwell AP; Centre for Public Health, Queens University of Belfast, Northern Ireland, UK., Kretzler M; Division of Nephrology, Department of Internal Medicine and.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan., Susztak K; Departments of Medicine and Genetics, University of Pennsylvania, Philadelphia, Pennsylvania., Colhoun HM; Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Krolewski A; Joslin Diabetes Center, Boston, Massachusetts., Paterson AD; The Hospital for Sick Children, Toronto, Ontario, Canada., Groop PH; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine and.; Department of Diabetes, Central Clinical School, Monash University, Melbourne, Victoria, Australia; and., Rich SS; Center for Public Health Genomics, School of Medicine, University of Virginia, Charlottesville, Virginia., Hirschhorn JN; Division of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.; Programs in Metabolism and Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts., Florez JC; Programs in Metabolism and Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts; jcflorez@mgh.harvard.edu.; Center for Genomic Medicine and.; Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.

Publikováno v: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2019 Oct; Vol. 30 (10), pp. 2000-2016. Date of Electronic Publication: 2019 Sep 19.