Switching between the Alternative Structures and Functions of a 2-Cys Peroxiredoxin, by Site-Directed Mutagenesis

Autor: Angelucci, F. ^{1, ⁎, †}, Saccoccia, F. ^{2, †}, Ardini, M. ¹, Boumis, G. ², Brunori, M. ², Di Leandro, L. ¹, Ippoliti, R. ¹, Miele, A.E. ², Natoli, G. ², Scotti, S. ¹, Bellelli, A. ^{2, ⁎}

Publikováno v: In Journal of Molecular Biology 15 November 2013 425(22):4556-4568

Truncating variants in the penultimate exon of TGFBR1 escaping nonsense-mediated mRNA decay cause Loeys-Dietz syndrome.

Autor: Fortugno P; Human Functional Genetics Laboratory, IRCCS San Raffaele Roma, Rome, Italy.; Università Telematica San Raffaele, Rome, Italy., Monetta R; Department of Life, Health, and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., Cinquina V; Division of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Rigon C; Clinical Genetics Unit, Department of Women and Children's Health, University of Padova, Padua, Italy.; IRP Città della Speranza, Padua, Italy., Boaretto F; Clinical Genetics Unit, Department of Women and Children's Health, University of Padova, Padua, Italy.; IRP Città della Speranza, Padua, Italy., De Luca C; Department of Life, Health, and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., Zoppi N; Division of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Di Leandro L; Department of Life, Health, and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., De Domenico E; Laboratory of Molecular and Cell Biology, Istituto Dermopatico dell'Immacolata IDI-IRCCS, Rome, Italy., Di Daniele A; Department of Life, Health, and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., Ippoliti R; Department of Life, Health, and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., Angelucci F; Department of Life, Health, and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., Di Cesare E; Department of Life, Health, and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., De Paulis R; Department of Cardiac Surgery, European Hospital, Rome, Italy., Salviati L; Clinical Genetics Unit, Department of Women and Children's Health, University of Padova, Padua, Italy.; IRP Città della Speranza, Padua, Italy., Colombi M; Division of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Brancati F; Human Functional Genetics Laboratory, IRCCS San Raffaele Roma, Rome, Italy. francesco.brancati@univaq.it.; Department of Life, Health, and Environmental Sciences, University of L'Aquila, L'Aquila, Italy. francesco.brancati@univaq.it., Ritelli M; Division of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.

Publikováno v: European journal of human genetics : EJHG [Eur J Hum Genet] 2023 May; Vol. 31 (5), pp. 596-601. Date of Electronic Publication: 2023 Jan 04.

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Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments.

Autor: Fata F; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy., Silvestri I; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy., Ardini M; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy., Ippoliti R; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy., Di Leandro L; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy., Demitri N; Elettra - Sincrotrone Trieste, S.S. 14 Km 163.5 in Area Science Park, 34149 Basovizza - Trieste, Italy., Polentarutti M; Elettra - Sincrotrone Trieste, S.S. 14 Km 163.5 in Area Science Park, 34149 Basovizza - Trieste, Italy., Di Matteo A; Institute of Molecular Biology and Pathology, National Research Council of Italy, c/o Department of Biochemical Sciences 'A Rossi Fanelli' - Sapienza University of Rome, 00185 Rome, Italy., Lyu H; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, Illinois 60612, United States., Thatcher GRJ; Department of Pharmacology & Toxicology, College of Pharmacy, the University of Arizona, Tucson, Arizona 85721, United States., Petukhov PA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Williams DL; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, Illinois 60612, United States., Angelucci F; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2021 Jul 09; Vol. 7 (7), pp. 1932-1944. Date of Electronic Publication: 2021 May 05.

Taking Advantage of the Morpheein Behavior of Peroxiredoxin in Bionanotechnology.

Autor: Ardini M; Department of Life, Health, and Environmental Sciences, University of L'Aquila, Piazzale Salvatore Tommasi 1, 67100 L'Aquila, Italy., Bellelli A; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Roma 'Sapienza', Piazzale Aldo Moro 5, 00185 Roma, Italy., Williams DL; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, Illinois 60612, United States., Di Leandro L; Department of Life, Health, and Environmental Sciences, University of L'Aquila, Piazzale Salvatore Tommasi 1, 67100 L'Aquila, Italy., Giansanti F; Department of Life, Health, and Environmental Sciences, University of L'Aquila, Piazzale Salvatore Tommasi 1, 67100 L'Aquila, Italy., Cimini A; Department of Life, Health, and Environmental Sciences, University of L'Aquila, Piazzale Salvatore Tommasi 1, 67100 L'Aquila, Italy., Ippoliti R; Department of Life, Health, and Environmental Sciences, University of L'Aquila, Piazzale Salvatore Tommasi 1, 67100 L'Aquila, Italy., Angelucci F; Department of Life, Health, and Environmental Sciences, University of L'Aquila, Piazzale Salvatore Tommasi 1, 67100 L'Aquila, Italy.

Publikováno v: Bioconjugate chemistry [Bioconjug Chem] 2021 Jan 20; Vol. 32 (1), pp. 43-62. Date of Electronic Publication: 2021 Jan 07.