Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide

Autor: Di Giglio, Maria Giulia, Muttenthaler, Markus, Harpsoe, Kasper, Liutkeviciute, Zita, Keov, Peter, Eder, Thomas, Rattei, Thomas, Arrowsmith, Sarah, Wray, Susan, Ales Marek, Elbert, Tomas, Alewood, Paul F., Gloriam, David E., Gruber, Christian W.

Publikováno v: Di Giglio, M G, Muttenthaler, M, Harpsøe, K, Liutkeviciute, Z, Keov, P, Eder, T, Rattei, T, Arrowsmith, S, Wray, S, Marek, A, Elbert, T, Alewood, P F, Gloriam, D E & Gruber, C W 2017, ' Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide ', Scientific Reports, vol. 7, 41002 . https://doi.org/10.1038/srep41002
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SCIENTIFIC REPORTS

Characterisation of G protein-coupled receptors (GPCR) relies on the availability of a toolbox of ligands that selectively modulate different functional states of the receptors. To uncover such molecules, we explored a unique strategy for ligand disc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7028aab9f070a0e0a6e13445925b2677
https://hdl.handle.net/11353/10.922051

Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide.

Autor: Di Giglio, Maria Giulia¹, Muttenthaler, Markus², Harpsøe, Kasper³, Liutkeviciute, Zita¹, Keov, Peter⁴, Eder, Thomas, Rattei, Thomas⁵, Arrowsmith, Sarah⁶, Wray, Susan⁶, Marek, Ales⁷, Elbert, Tomas⁷, Alewood, Paul F.², Gloriam, David E.³, Gruber, Christian W.

Publikováno v: Scientific Reports. 2/3/2017, p41002. 1p.