77 (PB067) - Discovery of I-0436650, a potent and selective SHP2 allosteric inhibitor for the treatment of RAS driven solid tumors

Autor: Puca, F., Fodale, V., Randazzo, P., Fabbrini, D., Missineo, A., Bisbocci, M., Esposito, S., Nibbio, M., Amaudrut, J., Colaceci, F., Sasso, R., Scalabrì, F., Loponte, S., Alli, C., Pucci, V., Montalbetti, C., Di Fabio, R., Petrocchi, A., Carugo, A., Toniatti, C.

Publikováno v: In European Journal of Cancer October 2022 174 Supplement 1:S26-S26

Synthesis and pharmacological properties of novel glycine antagonists

Autor: Donati, D., Di Fabio, R.

Publikováno v: In Pharmacochemistry Library 2000 31:239-245

Screening of ARHSP-TCC patients expands the spectrum of SPG11 mutations and includes a large scale gene deletion

Autor: Denora, Ps, Schlesinger, D, Casali, Carlo, Kok, F, Tessa, A, Boukhris, A, Azzedine, H, Dotti, Mt, Bruno, C, Truchetto, J, Biancheri, R, Fedirko, E, DI ROCCO, M, Bueno, C, Malandrini, A, Battini, R, Sickl, E, DE LEVA MF, BOESPFLUG TANGUY, O, Silvestri, G, Simonati, A, Said, E, Ferbert, A, Criscuolo, C, Heinimann, K, Modoni, A, Weber, P, Palmeri, S, Plasilova, M, Pauri, Flavia, Cassandrini, D, Battisti, C, Pini, A, Tosetti, M, Hauser, E, Masciullo, M, DI FABIO, R, Piccolo, F, Denis, E, Cioni, G, Massa, R, Della, Giustina, E, Calabrese, O, Melone, Ma, DE MICHELE, G, Federico, A, Bertini, E, Durr, A, Brockmann, K, VAN DER KNAAP MS, Zatz, M, Filla, A, Brice, A, Stevanin, G, Santorelli, Fm

Publikováno v: Human Mutation, 30(3), E500-E519. Wiley-Liss Inc.
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Denora, P S, Schlesinger, D, Casali, C, Kok, F, Tessa, A, Boukhris, A, Azzedine, H, Dotti, M T, Bruno, C, Truchetto, J, Biancheri, R, Fedirko, E, Di Rocco, M, Bueno, C, Malandrini, A, Battini, R, Sickl, E, de Leva, M F, Boespflug-Tanguy, O, Silvestri, G, Simonati, A, Said, E, Ferbert, A, Criscuolo, C, Heinimann, K, Modoni, A, Weber, P, Palmeri, S, Plasilova, M, Pauri, F, Cassandrini, D, Battisti, C, Pini, A, Tosetti, M, Hauser, E, Masciullo, M, Di Fabio, R, Piccolo, F, Denis, E, Cioni, G, Massa, R, la Giustina, E, Calabrese, O, Melone, M A B, De Michele, G, Federico, A, Bertini, E, Durr, A, Brockmann, K, van der Knaap, M S, Zatz, M, Filla, A, Brice, A, Stevanin, G & Santorelli, F M 2009, ' Screening of ARHSP-TCC patients expands the spectrum of SPG11 mutations and includes a large scale gene deletion ', Human Mutation, vol. 30, no. 3, pp. E500-E519 . https://doi.org/10.1002/humu.20945
Human mutation, 30(3), E500-E519. Wiley-Liss Inc.

Autosomal recessive spastic paraplegia with thinning of corpus callosum (ARHSP-TCC) is a complex form of HSP initially described in Japan but subsequently reported to have a worldwide distribution with a particular high frequency in multiple families

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6ba3c03e72db209b2dcfa43f19a30e
http://hdl.handle.net/2108/39066

Infantile-onset Hereditary spastic paraplegia associated with SPAST mutations (SPG4): clinical and follow-up studies

Autor: Casali C, Piccolo F, Marcotulli C, Santorelli F, Tessa A, Di Fabio R, D’Angelo MG, Serrao M, Pierelli F, MELONE, Mariarosa Anna Beatrice

Introduction: Hereditary spastic paraplegia (HSP) associated with SPAST mutations (SPG4) is the most frequent form of autosomal dominant HSP accounting approximately for 40% of reported cases. The phenotype associated with HSP due to mutation in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3977::fef28bb14990d7fae089d1f1d8f63d01
http://hdl.handle.net/11591/222742

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