GM1 structural requirements to mediate neuronal functions.

Autor: Fazzari M; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Lunghi G; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Di Biase E; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Maggioni M; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Carsana EV; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Cioccarelli L; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Vigani L; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Loberto N; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Aureli M; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Mauri L; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Ciampa MG; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Valsecchi M; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Takato K; Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan., Imamura A; Department of Applied Bioorganic Chemistry, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.; Institute for Glyco-core Research (iGCORE), Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan., Ishida H; Department of Applied Bioorganic Chemistry, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.; Institute for Glyco-core Research (iGCORE), Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan., Ben Mariem O; Dipartimento di Scienze Farmacologiche e Biomolecolari 'Rodolfo Paoletti', Università degli Studi di Milano, Milano, Italy., Saporiti S; Analytical Excellence & Program Management, Merck Serono S.p.A, Rome, Italy., Palazzolo L; Dipartimento di Scienze Farmacologiche e Biomolecolari 'Rodolfo Paoletti', Università degli Studi di Milano, Milano, Italy., Chiricozzi E; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy. elena.chiricozzi@unimi.it., Eberini I; Dipartimento di Scienze Farmacologiche e Biomolecolari 'Rodolfo Paoletti', Università degli Studi di Milano, Milano, Italy.; Data Science Research Center, Università degli Studi di Milano, Milano, Italy., Sonnino S; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy. sandro.sonnino@unimi.it.

Publikováno v: Glycoconjugate journal [Glycoconj J] 2023 Dec; Vol. 40 (6), pp. 655-668. Date of Electronic Publication: 2023 Dec 15.

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Loss of Lipid Carrier ApoE Exacerbates Brain Glial and Inflammatory Responses after Lysosomal GBA1 Inhibition.

Autor: Connolly KJ; Departments of Psychiatry and Neurology Harvard Medical School, Neuroregeneration Institute, McLean Hospital, Belmont, MA 02478, USA., Margaria J; Departments of Psychiatry and Neurology Harvard Medical School, Neuroregeneration Institute, McLean Hospital, Belmont, MA 02478, USA., Di Biase E; Departments of Psychiatry and Neurology Harvard Medical School, Neuroregeneration Institute, McLean Hospital, Belmont, MA 02478, USA., Cooper O; Departments of Psychiatry and Neurology Harvard Medical School, Neuroregeneration Institute, McLean Hospital, Belmont, MA 02478, USA., Hallett PJ; Departments of Psychiatry and Neurology Harvard Medical School, Neuroregeneration Institute, McLean Hospital, Belmont, MA 02478, USA., Isacson O; Departments of Psychiatry and Neurology Harvard Medical School, Neuroregeneration Institute, McLean Hospital, Belmont, MA 02478, USA.

Publikováno v: Cells [Cells] 2023 Nov 02; Vol. 12 (21). Date of Electronic Publication: 2023 Nov 02.

GM1 oligosaccharide efficacy against α-synuclein aggregation and toxicity in vitro.

Autor: Fazzari M; Department of Medical Biotechnology and Translational Medicine, University of Milano, 20054 Segrate, Milano, Italy., Di Biase E; Department of Medical Biotechnology and Translational Medicine, University of Milano, 20054 Segrate, Milano, Italy., Zaccagnini L; UK Dementia Research Institute at UCL, London, UK., Henriques A; Neuro-Sys, 410 Chemin Départemental 60, 13120 Gardanne, France., Callizot N; Neuro-Sys, 410 Chemin Départemental 60, 13120 Gardanne, France., Ciampa MG; Department of Medical Biotechnology and Translational Medicine, University of Milano, 20054 Segrate, Milano, Italy., Mauri L; Department of Medical Biotechnology and Translational Medicine, University of Milano, 20054 Segrate, Milano, Italy., Carsana EV; Department of Medical Biotechnology and Translational Medicine, University of Milano, 20054 Segrate, Milano, Italy., Loberto N; Department of Medical Biotechnology and Translational Medicine, University of Milano, 20054 Segrate, Milano, Italy., Aureli M; Department of Medical Biotechnology and Translational Medicine, University of Milano, 20054 Segrate, Milano, Italy., Mari L; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Civera M; Department of Chemistry, University of Milano, Milan, Italy., Vasile F; Department of Chemistry, University of Milano, Milan, Italy., Sonnino S; Department of Medical Biotechnology and Translational Medicine, University of Milano, 20054 Segrate, Milano, Italy. Electronic address: sandro.sonnino@unimi.it., Bartels T; UK Dementia Research Institute at UCL, London, UK., Chiricozzi E; Department of Medical Biotechnology and Translational Medicine, University of Milano, 20054 Segrate, Milano, Italy. Electronic address: elena.chiricozzi@unimi.it., Lunghi G; Department of Medical Biotechnology and Translational Medicine, University of Milano, 20054 Segrate, Milano, Italy.

Publikováno v: Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2023 Sep; Vol. 1868 (9), pp. 159350. Date of Electronic Publication: 2023 Jun 16.

Glycosphingolipids.

Autor: Chiricozzi E; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Aureli M; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Mauri L; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Di Biase E; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Lunghi G; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Fazzari M; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Valsecchi M; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Carsana EV; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Loberto N; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Prinetti A; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy., Sonnino S; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy. sandro.sonnino@unimi.it.

Publikováno v: Advances in experimental medicine and biology [Adv Exp Med Biol] 2021; Vol. 1325, pp. 61-102.