Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Diêgo Madureira de Oliveira"'
Autor:
Ligia Canongia de Abreu Cardoso Duarte, Caroline Ferreira Fratteli, Calliandra Maria de Sousa Silva, Alexandre Sampaio Rodrigues Pereira, Jamila Reis de Oliveira, Rafael Martins de Morais, Diêgo Madureira de Oliveira, Izabel Cristina Rodrigues da Silva
Publikováno v:
DNA, Vol 4, Iss 3, Pp 328-336 (2024)
Thyroid gland carcinoma (TGC), though only 1% of all carcinomas, is the most common endocrine neoplasm with an increasing incidence since the 1990s. Of the TGC types, papillary thyroid carcinoma (PTC) is the most common and has the best overall progn
Externí odkaz:
https://doaj.org/article/6fc2fb9f78f9475693f94634083e7fd7
Autor:
Tales Henrique Andrade da Mota, Ana Flávia Reis Guimarães, Amandda Évelin Silva de Carvalho, Felipe Saldanha- de Araujo, Giselle Pinto de Faria Lopes, Fábio Pittella-Silva, Doralina do Amaral Rabello, Diêgo Madureira de Oliveira
Publikováno v:
Repositório Institucional da UnB
Universidade de Brasília (UnB)
instacron:UNB
Universidade de Brasília (UnB)
instacron:UNB
BACKGROUND: The inhibition of the enzyme telomerase (TERT) has been widely investigated as a new pharmacological approach for cancer treatment, but its real potential and the biochemical consequences are not totally understood. OBJECTIVE: Here, we in
Autor:
Rafael Martins de Morais, Jamila Reis de Oliveira, Calliandra M Sousa Silva, Jéssica Nayane Gomes de Souza, Ligia C A Cardoso-Duarte, Izabel Cristina Rodrigues da Silva, Diêgo Madureira de Oliveira, Alexandre Sampaio Rodrigues Pereira, Alaor Barra Sobrinho, Caroline Ferreira Fratelli, Renata de Souza Freitas
Publikováno v:
The International Journal of Biological Markers. 36:21-26
Introduction Papillary thyroid cancer corresponds to approximately 1% of all carcinomas; nevertheless, it is the most prevalent endocrine neoplasm in the world. Studies reveal that the BAX (−248 G > A) polymorphism may be associated with negative r
Autor:
Tales Henrique Andrade da Mota, Ricardo Camargo, Estefânia Rodrigues Biojone, Ana Flávia Reis Guimarães, Fabio Pittella-Silva, Diêgo Madureira de Oliveira
Publikováno v:
Genes. 14:691
Telomeres and telomerase are closely linked to uncontrolled cellular proliferation, immortalization and carcinogenesis. Telomerase has been largely studied in the context of cancer, including leukemias. Deregulation of human telomerase gene hTERT is
Autor:
Diêgo Madureira de Oliveira, Stevens K. Rehen, Jorge Clarêncio, Helena L. Borges, Giselle Pinto de Faria Lopes, Eudes da Silva Velozo, Ezequiel Pereira, Tereza C C Silva, Bruno P.S. Pitanga, N.J. Menezes-Filho, Rafael dos Santos Costa, Silvia Lima Costa, Vivaldo Moura-Neto, Songeli Menezes Freire
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 18:1386-1393
Background: A glioblastoma is a primary CNS tumor that is more aggressive and lethal than other brain tumors. Its location, rapid proliferation, invasive growth, angiogenesis and immunosuppression are the main factors that limit its treatment, making
Autor:
Diêgo Madureira de Oliveira, Claudia C. Gatto, Guilherme G. da Silva, Daniel da Silva Arcanjo, Cássia de Q. O. Cavalcante
Publikováno v:
New Journal of Chemistry. 43:11209-11221
The current work reports the synthesis and investigation by physical-chemistry and spectroscopic methods of three dithiocarbazates (2-acetylpyridine-S-allyl-dithiocarbazate – HL1; 2-acetylpyridine-S-p-bromobenzyl-dithiocarbazate – HL2; and 2-acet
Autor:
Claudia C. Gatto, Yuri A.O. Só, Diêgo Madureira de Oliveira, Francielle C. Lima, Ricardo Gargano
Publikováno v:
Journal of inorganic biochemistry. 224
The present work reports the synthesis and a structural study of two novel dithiocarbazate, the 4,6-diacetylresorcinol-S-benzyldithiocarbazate (H3L1) and the 4,6-diacetylresorcinol-bis(S-benzyldithiocarbazate) (H4L2), and their Ni(II) complexes, [Ni(
Autor:
Diêgo Madureira de Oliveira, Antonio R. Lucena-Araujo, Fábio Morato de Oliveira, Juliana Carvalho Alves-Silva, Doralina do Amaral Rabello, Felipe Saldanha-Araujo, Eduardo Magalhães Rego, Martha de Oliveira Bravo, Fabio Pittella-Silva
Publikováno v:
Environmental and Molecular Mutagenesis. 58:654-661
Chromosomal alterations are commonly detected in patients with chronic lymphocytic leukemia (CLL) and impact disease pathogenesis, prognosis, and progression. Telomerase expression (hTERT), its activity and the telomere length are other important pre
Autor:
Doralina do Amaral Rabello Ramos, Diêgo Madureira de Oliveira, Ana Flávia R. Guimarãesb, Fabio Pittella Silva, Karollyne S. Morais
Publikováno v:
Anti-Cancer Drugs. 28:750-756
Telomerase is an enzyme responsible for telomere maintenance in almost all human cancer cells, but generally not expressed in somatic ones. Therefore, antitelomerase therapy is a potentially revolutionary therapeutic strategy, and the antitumor activ
Autor:
Karollyne S. Morais, Diêgo Madureira de Oliveira, Guilherme G. da Silva, Daniel da Silva Arcanjo
Publikováno v:
Current topics in medicinal chemistry. 20(6)
The alternative lengthening of telomere (ALT) is a pathway responsible for cell immortalization in some kinds of tumors. Since the first description of ALT is relatively recent in the oncology field, its mechanism remains elusive, but recent works ad