Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Diána Balogh‐Weiser"'
Autor:
Anita Csorba, Gábor Katona, Mária Budai-Szűcs, Diána Balogh-Weiser, Anna Maria Fadda, Carla Caddeo, Ágnes Ildikó Takács, Péter Mátyus, György T. Balogh, Zoltán Zsolt Nagy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Ascorbic acid (AA) has a pivotal role in corneal wound healing via stimulating the biosynthesis of highly organized extracellular matrix components, but its rapid degradation and low corneal permeability limits its therapeutic effects. In th
Externí odkaz:
https://doaj.org/article/571c73be8b414fdab6a52cf6f6ab5177
Autor:
Anita Csorba, Gábor Katona, Mária Budai-Szűcs, Diána Balogh-Weiser, Péter Molnár, Erika Maka, Adrienn Kazsoki, Márton Vajna, Romána Zelkó, Zoltán Zsolt Nagy, György T. Balogh
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1623 (2024)
Cystinosis is a low-prevalence lysosomal storage disease. The pathomechanism involves abnormal functioning of the cystinosine lysosomal cystine transporter (CTNS), causing intraliposomal accumulation of the amino acid cysteine disulfide, which crysta
Externí odkaz:
https://doaj.org/article/9c83360b3fc04dd2b09ffd5402eeb1d6
Autor:
Diána Balogh-Weiser, Alexandra Molnár, Gergő D. Tóth, Gábor Koplányi, József Szemes, Balázs Decsi, Gábor Katona, Maryana Salamah, Ferenc Ender, Anita Kovács, Szilvia Berkó, Mária Budai-Szűcs, György T. Balogh
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1174 (2023)
The application of enzyme-based therapies has received significant attention in modern drug development. Lipases are one of the most versatile enzymes that can be used as therapeutic agents in basic skin care and medical treatment related to excessiv
Externí odkaz:
https://doaj.org/article/370da88930404a20b82123c6c15dac79
Autor:
Anna Vincze, Gergely Dékány, Richárd Bicsak, András Formanek, Yves Moreau, Gábor Koplányi, Gergely Takács, Gábor Katona, Diána Balogh-Weiser, Ádám Arany, György T. Balogh
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 899 (2023)
In vitro non-cellular permeability models such as the parallel artificial membrane permeability assay (PAMPA) are widely applied tools for early-phase drug candidate screening. In addition to the commonly used porcine brain polar lipid extract for mo
Externí odkaz:
https://doaj.org/article/2b1e105f93424058b5437bbca5b355c0
Autor:
György T. Balogh, Balázs Decsi, Réka Krammer, Balázs Kenéz, Ferenc Ender, Tamás Hergert, Diána Balogh-Weiser
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1269 (2022)
The investigation of liver-related metabolic stability of a drug candidate is a widely used key strategy in early-stage drug discovery. Metalloporphyrin-based biomimetic catalysts are good and well-described models of the function of CyP450 in hepato
Externí odkaz:
https://doaj.org/article/82769ac83c7842389103ca1709b2c3f8
Autor:
Gábor Koplányi, Evelin Sánta-Bell, Zsófia Molnár, Gergő Dániel Tóth, Muriel Józó, András Szilágyi, Ferenc Ender, Béla Pukánszky, Beáta G. Vértessy, László Poppe, Diána Balogh-Weiser
Publikováno v:
Catalysts, Vol 11, Iss 10, p 1149 (2021)
Immobilization of the recombinant, plant-derived Petroselinum crispum phenylalanine ammonia lyase (PcPAL) in electrospun matrices have the potential to create promising, easy-to-use biocatalysts. Polylactic acid (PLA) a biologically inert, commercial
Externí odkaz:
https://doaj.org/article/14c701d0b36342cca167cc2d6c88d274
Autor:
Gergő Dániel Tóth, Adrienn Kazsoki, Benjámin Gyarmati, András Szilágyi, Gábor Vasvári, Gábor Katona, Lajos Szente, Romána Zelkó, László Poppe, Diána Balogh-Weiser, György T. Balogh
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 972 (2021)
Enzyme replacement therapies (ERT) have been of great help over the past 30 years in the treatment of various lysosomal storage disorders, including chronic pancreatitis and its common complication, exocrine pancreatic insufficiency. Research shows t
Externí odkaz:
https://doaj.org/article/5ca461ac3c9440a8b80d197da54265ab
Autor:
Ali Obaid Imarah, Pál Csuka, Naran Bataa, Balázs Decsi, Evelin Sánta-Bell, Zsófia Molnár, Diána Balogh-Weiser, László Poppe
Publikováno v:
Catalysts, Vol 11, Iss 4, p 483 (2021)
In this study, we investigated the influence of different modes of magnetic mixing on effective enzyme activity of aspartate ammonia-lyase from Pseudomonas fluorescens immobilized onto epoxy-functionalized magnetic nanoparticles by covalent binding (
Externí odkaz:
https://doaj.org/article/9dbcb19606d041cb8154c6f3d8f66444
Autor:
Diána Balogh-Weiser, Balázs Decsi, Réka Krammer, Gergő Dargó, Ferenc Ender, János Mizsei, Róbert Berkecz, Benjámin Gyarmati, András Szilágyi, Róbert Tőtős, Csaba Paizs, László Poppe, György T. Balogh
Publikováno v:
Nanomaterials, Vol 10, Iss 12, p 2329 (2020)
The dual functionalization of magnetic nanoparticles with inert (methyl) and reactive (aminopropyl) groups enables efficient immobilization of synthetic metalloporphyrins (such as 5,10,15,20-tetrakis(2,3,4,5,6-pentafluorophenyl)iron(II) porphyrin and
Externí odkaz:
https://doaj.org/article/5ba7747cf12a48a6a57f10e603dfa85b
Autor:
Evelin Sánta-Bell, Zsófia Molnár, Andrea Varga, Flóra Nagy, Gábor Hornyánszky, Csaba Paizs, Diána Balogh-Weiser, László Poppe
Publikováno v:
Molecules, Vol 24, Iss 22, p 4146 (2019)
This article overviews the numerous immobilization methods available for various biocatalysts such as whole-cells, cell fragments, lysates or enzymes which do not require preliminary enzyme purification and introduces an advanced approach avoiding th
Externí odkaz:
https://doaj.org/article/e723714cbb31483da8f6dd5860fdbad4