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pro vyhledávání: '"Dhwani S. Korde"'
Autor:
Dhwani S. Korde, Christian Humpel
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 165 (2024)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that is characterized by amyloid-beta (Aβ) plaques and tau neurofibrillary tangles (NFT). Modelling aspects of AD is challenging due to its complex multifactorial etiology and pa
Externí odkaz:
https://doaj.org/article/5bb52e1e30a748fdaa9f5c8ca1746252
Autor:
Dhwani S. Korde, Christian Humpel
Publikováno v:
MethodsX, Vol 9, Iss , Pp 101779- (2022)
Alzheimer´s disease is characterized by hyperphosphorylated tau neurofibrillary tangles and beta-amyloid plaques. Both molecules can be easily measured in human fluids or tissue extracts by immunoassays. However, the different molecular weight speci
Externí odkaz:
https://doaj.org/article/3b0b8ec4f18e44838fa1617715229db4
Autor:
Dhwani S. Korde, Christian Humpel
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1164 (2022)
Tau pathology extends throughout the brain in a prion-like fashion through connected brain regions. However, the details of the underlying mechanisms are incompletely understood. The present study aims to examine the spreading of P301S aggregated tau
Externí odkaz:
https://doaj.org/article/dfb3ed49f6ac486685d167a8720d7f11
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 5, p 153 (2022)
Background: Platelets (thrombocytes) are small anuclear cells that play an important role in blood clotting. They are activated and dysfunctional in brain disorders, such as Alzheimer’s disease (AD) and depression. Platelets express the amyloid-pre
Externí odkaz:
https://doaj.org/article/402276991fe047a0ad2dae5f566667df
Publikováno v:
Pharmacology. 108:204-212
The nucleus basalis of Meynert (nBM) is the major source of cholinergic neurons in the basal forebrain, which require nerve growth factor (NGF) for their survival. Melatonin, a pleiotropic hormone, has been shown to exert neuroprotection in several e
Publikováno v:
Frontiers in bioscience (Landmark edition). 27(5)
Platelets (thrombocytes) are small anuclear cells that play an important role in blood clotting. They are activated and dysfunctional in brain disorders, such as Alzheimer's disease (AD) and depression. Platelets express the amyloid-precursor protein