Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Dhruv K. Pant"'
Autor:
Matthew R. Lawrence-Paul, Tien-chi Pan, Dhruv K. Pant, Natalie N. C. Shih, Yan Chen, George K. Belka, Michael Feldman, Angela DeMichele, Lewis A. Chodosh
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background Evolutionary models of breast cancer progression differ on the extent to which metastatic potential is pre-encoded within primary tumors. Although metastatic recurrences often harbor putative driver mutations that are not detected
Externí odkaz:
https://doaj.org/article/e39183bc9dda4422b08a07e9f44a1073
Autor:
Saisai Chen, Matt R. Paul, Christopher J. Sterner, George K. Belka, Dezhen Wang, Peining Xu, Amulya Sreekumar, Tien-chi Pan, Dhruv K. Pant, Igor Makhlin, Angela DeMichele, Clementina Mesaros, Lewis A. Chodosh
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-20 (2023)
Abstract Background Breast cancer mortality is principally due to recurrent disease that becomes resistant to therapy. We recently identified copy number (CN) gain of the putative membrane progesterone receptor PAQR8 as one of four focal CN alteratio
Externí odkaz:
https://doaj.org/article/c264bed9ee0941cbb0795a4506954132
Autor:
Jason R. Ruth, Dhruv K. Pant, Tien-chi Pan, Hans E. Seidel, Sanjeethan C. Baksh, Blaine A. Keister, Rita Singh, Christopher J. Sterner, Suzanne J. Bakewell, Susan E. Moody, George K. Belka, Lewis A. Chodosh
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-23 (2021)
Abstract Background Breast cancer mortality is principally due to tumor recurrence, which can occur following extended periods of clinical remission that may last decades. While clinical latency has been postulated to reflect the ability of residual
Externí odkaz:
https://doaj.org/article/6df180a2332146bc930a618f952a3805
Autor:
Brett L. Ecker, Jun Y. Lee, Christopher J. Sterner, Aaron C. Solomon, Dhruv K. Pant, Fei Shen, Javier Peraza, Lauren Vaught, Samyukta Mahendra, George K. Belka, Tien-chi Pan, Kathryn H. Schmitz, Lewis A. Chodosh
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-16 (2019)
Abstract Background Obesity is associated with an increased risk of breast cancer recurrence and cancer death. Recurrent cancers arise from the pool of residual tumor cells, or minimal residual disease (MRD), that survives primary treatment and persi
Externí odkaz:
https://doaj.org/article/f7dc2d4437b94873a91269290196df2f
Publikováno v:
Haematologica, Vol 98, Iss 6 (2013)
Trithorax and polycomb group proteins antagonistically regulate the transcription of many genes, and cancer can result from the disruption of this regulation. Deregulation of trithorax function occurs through chromosomal translocations involving the
Externí odkaz:
https://doaj.org/article/57bd97075adb442191061e62834f1d0e
Autor:
Lewis A. Chodosh, Jason R. Ruth, James V. Alvarez, Kristi R. Chakrabarti, Dhruv K. Pant, Tien-Chi Pan, Yi Feng
PDF file 645K, This file contains supplemental figures that provided supportive evidence to the main conclusion described in the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be234b4705a0e95b5ea63d84ecef1e5
https://doi.org/10.1158/2159-8290.22530752.v1
https://doi.org/10.1158/2159-8290.22530752.v1
Autor:
Lewis A. Chodosh, Jason R. Ruth, James V. Alvarez, Kristi R. Chakrabarti, Dhruv K. Pant, Tien-Chi Pan, Yi Feng
PDF file 70K, This file contains detailed information about the experimental procedures and the reagents used in the assays described in the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cec2c4e129f7268b9fd9b2370796bb
https://doi.org/10.1158/2159-8290.22530749.v1
https://doi.org/10.1158/2159-8290.22530749.v1
Autor:
Lewis A. Chodosh, Jason R. Ruth, James V. Alvarez, Kristi R. Chakrabarti, Dhruv K. Pant, Tien-Chi Pan, Yi Feng
PDF file 49K, This file contains text descriptions for each corresponding supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b51e7521c76029a7d2b1ea7bc57af56
https://doi.org/10.1158/2159-8290.22530755.v1
https://doi.org/10.1158/2159-8290.22530755.v1
(A) qRT-PCR analysis of Cerk mRNA expression in Cerk knockdown tumor cell lines. (B) Percentage of eGFP-positive and mCherry-positive cells at timepoints in Figure 3A in control cohort and (C) in a second shRNA cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371bcfcff8fc2caee880e95a48d99cb2
https://doi.org/10.1158/0008-5472.22404368.v1
https://doi.org/10.1158/0008-5472.22404368.v1
(A) Quantification of MTB/TAN primary tumor cell lines expressing pk1, Cerk or G198D- Cerk withdrawn from doxycycline 72 hr then stained for Ki67. (B) Quantification of MTB/TAN primary tumor cell lines expressing MLP, a control scrambled shRNA, shCer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f36e3679f414aee3113d119994c1d12
https://doi.org/10.1158/0008-5472.22404371
https://doi.org/10.1158/0008-5472.22404371