Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Dhruba K. Chattoraj"'
Autor:
Heung Jin Jeon, Yonho Lee, Monford Paul Abishek N, Xun Wang, Dhruba K. Chattoraj, Heon M. Lim
Publikováno v:
PLoS Genetics, Vol 17, Iss 10 (2021)
In bacteria, small non-coding RNAs (sRNAs) bind to target mRNAs and regulate their translation and/or stability. In the polycistronic galETKM operon of Escherichia coli, binding of the Spot 42 sRNA to the operon transcript leads to the generation of
Externí odkaz:
https://doaj.org/article/52bc1589e2764e12ab71d5c45ab27b72
Autor:
Heung Jin Jeon, Changjo Kang, Monford Paul Abishek N, Yonho Lee, Xun Wang, Dhruba K. Chattoraj, Heon M. Lim
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
In bacteria, mRNA decay is a major mechanism for regulating gene expression. In Escherichia coli, mRNA decay initiates with endonucleolytic cleavage by RNase E. Translating ribosomes impede RNase E cleavage, thus providing stability to mRNA. In trans
Externí odkaz:
https://doaj.org/article/942dfacaaed14647962da3b53a1556fd
Autor:
Bhabatosh Das, Dhruba K. Chattoraj
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/392772febbb74bc7b087b5669ca439aa
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The human pathogen, Vibrio cholerae, belongs to the 10% of bacteria in which the genome is divided. Each of its two chromosomes, like bacterial chromosomes in general, replicates from a unique origin at fixed times in the cell cycle. Chr1 initiates f
Externí odkaz:
https://doaj.org/article/87fac8e586d949ceabbb65686940b502
Publikováno v:
BioTechniques, Vol 35, Iss 1, Pp 90-98 (2003)
Identification of nucleotides used for RNA chain initiation or for contacting DNA binding proteins is basic to our understanding of gene regulation. Normally, a radioactive primer is used to copy RNA or DNA. The polymerase extension stops at free end
Externí odkaz:
https://doaj.org/article/e8849ade0af245fe868c88920b1d9667
Publikováno v:
mBio, Vol 5, Iss 3 (2014)
ABSTRACT Bacterial ParA and ParB proteins are best known for their contribution to plasmid and chromosome segregation, but they may also contribute to other cell functions. In segregation, ParA interacts with ParB, which binds to parS centromere-anal
Externí odkaz:
https://doaj.org/article/ae984da185684dd28a663ca0a5f7f080
Autor:
Ryosuke Kadoya, Dhruba K. Chattoraj
Publikováno v:
mBio, Vol 3, Iss 3 (2012)
ABSTRACT Vibrio cholerae has two chromosomes (chrI and chrII) whose replication and segregation are under different genetic controls. The region covering the replication origin of chrI resembles that of the Escherichia coli chromosome, and both origi
Externí odkaz:
https://doaj.org/article/85e98c92db78453bae8bc60a9fb6648d
Autor:
Satpal S Chodha, Adam C Brooks, Peter J Davis, Revathy Ramachandran, Dhruba K Chattoraj, Ling Chin Hwang
Publikováno v:
Nucleic Acids Research.
Dynamic protein gradients are exploited for the spatial organization and segregation of replicated chromosomes. However, mechanisms of protein gradient formation and how that spatially organizes chromosomes remain poorly understood. Here, we have det
Autor:
Yanqi Hou, Pankaj Kumar, Monika Aggarwal, Farzad Sarkari, Karen M. Wolcott, Dhruba K. Chattoraj, Elliott Crooke, Rahul Saxena
Publikováno v:
Science Advances. 8
DnaA, the initiator of Escherichia coli chromosomal replication, has in its adenosine triphosphatase (ATPase) domain residues required for adenosine 5′-triphosphate (ATP) binding and membrane attachment. Here, we show that D118Q substitution in the
Publikováno v:
Nucleic Acids Res
Studies of bacterial chromosomes and plasmids indicate that their replication initiator proteins bind to origins of replication at many double-stranded sites and also at AT-rich regions where single-stranded DNA is exposed during origin opening. Sing