Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dhriti Sinha"'
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Streptococcus pneumoniae
Externí odkaz:
https://doaj.org/article/31597d02854041fbbadc5520bfb02f07
Autor:
Dhriti Sinha, Nicholas R. De Lay
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The C-terminal domain (CTD) of the major endoribonuclease RNase E not only serves as a scaffold for the central RNA decay machinery in gram-negative bacteria but also mediates coupled degradation of small regulatory RNAs (sRNAs) and their cognate tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10de3e51529258baf80a23a06ab21b46
https://doi.org/10.1073/pnas.2208022119
https://doi.org/10.1073/pnas.2208022119
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
mBio
mBio
RNases perform indispensable functions in regulating gene expression in many bacterial pathogens by processing and/or degrading RNAs. Despite the pivotal role of RNases in regulating bacterial virulence factors, the functions of RNases have not yet b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076cc79bc60e6591fc324a60d1299863
https://journals.asm.org/doi/10.1128/mBio.02385-21
https://journals.asm.org/doi/10.1128/mBio.02385-21
Autor:
Nicholas R. De Lay, Ben F. Luisi, Dhriti Sinha, Katarzyna J Bandyra, Alzbeta Roeselová, Todd A. Cameron, Tom Dendooven
Publikováno v:
Molecular Cell
Summary Polynucleotide phosphorylase (PNPase) is an ancient exoribonuclease conserved in the course of evolution and is found in species as diverse as bacteria and humans. Paradoxically, Escherichia coli PNPase can act not only as an RNA degrading en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79b4febf879b41ea8bbab07b5ee0c3b
https://www.repository.cam.ac.uk/handle/1810/323156
https://www.repository.cam.ac.uk/handle/1810/323156
Publikováno v:
Nucleic Acids Research
In many Gram-negative and some Gram-positive bacteria, small regulatory RNAs (sRNAs) that bind the RNA chaperone Hfq have a pivotal role in modulating virulence, stress responses, metabolism and biofilm formation. These sRNAs recognize transcripts th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a19a5287a3aa31cd25255dffdf3bc66
http://europepmc.org/articles/PMC7145675
http://europepmc.org/articles/PMC7145675
Autor:
Ho-Ching Tiffany Tsui, John D. Richardson, Jiaqi J. Zheng, Dhriti Sinha, Malcolm E. Winkler, Nicholas R De Lay
Publikováno v:
J Bacteriol
Posttranscriptional gene regulation often involves RNA-binding proteins that modulate mRNA translation and/or stability either directly through protein-RNA interactions or indirectly by facilitating the annealing of small regulatory RNAs (sRNAs). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a35441c9d9206110d99668de4f49fa
https://europepmc.org/articles/PMC7925082/
https://europepmc.org/articles/PMC7925082/
Autor:
Dhriti Sinha, Jiaqi J. Zheng, Malcolm E. Winkler, John D. Richardson, Nicholas R. DeLay, Ho-Ching Tiffany Tsui
Post-transcriptional gene regulation often involves RNA-binding proteins that modulate mRNA translation and/or stability either directly through protein-RNA interactions or indirectly by facilitating the annealing of small regulatory RNAs (sRNAs). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38adf462a5528b7b7123602930fa180c
https://doi.org/10.1101/2020.06.23.167635
https://doi.org/10.1101/2020.06.23.167635
Publikováno v:
RNA. 24:1496-1511
Small regulatory RNAs (sRNAs) are an important class of bacterial post-transcriptional regulators that control numerous physiological processes, including stress responses. In Gram-negative bacteria including Escherichia coli, the RNA chaperone Hfq b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9802f39b6cd4d30581467c37e9b10f3
https://doi.org/10.1261/rna.067181.118
https://doi.org/10.1261/rna.067181.118
Autor:
Kurt Zimmer, Dhriti Sinha, Douglas B. Rusch, Nicholas R De Lay, Malcolm E. Winkler, Todd A. Cameron
Streptococcus pneumoniae (pneumococcus) is a major human respiratory pathogen and a leading cause of bacterial pneumonia worldwide. Small regulatory RNAs (sRNAs), which often act by posttranscriptionally regulating gene expression, have been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066275bd751b3de0501d0098dae84b25
https://europepmc.org/articles/PMC6597385/
https://europepmc.org/articles/PMC6597385/
Autor:
Johanna Liinamaria Syrjänen, Dhriti Sinha, Ben F. Luisi, Nicholas R De Lay, Katarzyna J Bandyra
Publikováno v:
RNA. 22:360-372
In all bacterial species examined thus far, small regulatory RNAs (sRNAs) contribute to intricate patterns of dynamic genetic regulation. Many of the actions of these nucleic acids are mediated by well-characterized chaperones such as the Hfq protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14db4eb13ac5352e5fe49b5b3ee5dd36
https://doi.org/10.1261/rna.052886.115
https://doi.org/10.1261/rna.052886.115