Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dhivya Ramakrishnan"'
Publikováno v:
TNOA Journal of Ophthalmic Science and Research, Vol 59, Iss 1, Pp 28-31 (2021)
Aim: The primary outcome is to assess visual outcomes following cataract surgery in axial myopic patients. The secondary outcome assessed is perioperative complications rate due to high axial length. Materials and Methods: Type of study: It was a ret
Externí odkaz:
https://doaj.org/article/601da6fc83224ae8be71f04ee07a9555
Autor:
Congrong Niu, Christine M Livingston, Li Li, Rudolf K Beran, Stephane Daffis, Dhivya Ramakrishnan, Dara Burdette, Leanne Peiser, Eduardo Salas, Hilario Ramos, Mei Yu, Guofeng Cheng, Michel Strubin, William E Delaney, Simon P Fletcher
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169648 (2017)
The structural maintenance of chromosome 5/6 complex (Smc5/6) is a restriction factor that represses hepatitis B virus (HBV) transcription. HBV counters this restriction by expressing HBV X protein (HBx), which targets Smc5/6 for degradation. However
Externí odkaz:
https://doaj.org/article/289b65f6ddb14f2da1dab20a156f9d07
Autor:
Christine M. Livingston, Dhivya Ramakrishnan, Michel Strubin, Simon P. Fletcher, Rudolf K. Beran
Publikováno v:
Viruses, Vol 9, Iss 4, p 69 (2017)
Hepatitis B X protein (HBx) plays an essential role in the hepatitis B virus (HBV) replication cycle, but the function of HBx has been elusive until recently. It was recently shown that transcription from the HBV genome (covalently-closed circular DN
Externí odkaz:
https://doaj.org/article/ebe438cd3f0b4e798ddc6665a854dacc
Autor:
Dong Whan Lee, Dhivya Ramakrishnan, John Valenta, Ian F Parney, Kayla J Bayless, Raquel Sitcheran
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57489 (2013)
High-grade gliomas, such as glioblastomas (GBMs), are very aggressive, invasive brain tumors with low patient survival rates. The recent identification of distinct glioma tumor subtypes offers the potential for understanding disease pathogenesis, res
Externí odkaz:
https://doaj.org/article/b3a097573fc04604882be9741ee47b59
Autor:
Fabien Abdul, Aurélie Diman, Bastien Baechler, Dhivya Ramakrishnan, Dmytro Kornyeyev, Rudolf K. Beran, Simon P. Fletcher, Michel Strubin
Publikováno v:
Nature Structural & Molecular Biology. 29:922-931
In addition to its role in chromosome maintenance, the six-membered Smc5/6 complex functions as a restriction factor that binds to and transcriptionally silences viral and other episomal DNA. However, the underlying mechanism is unknown. Here, we sho
Autor:
Fabien Abdul, Aurélie Diman, Bastien Baechler, Dhivya Ramakrishnan, Dmytro Kornyeyev, Rudolf K. Beran, Simon P. Fletcher, Michel Strubin
Publikováno v:
Nature Structural & Molecular Biology.
Autor:
Leanne Peiser, Jessica Davies, Divya Pattabiraman, Ruth Chu, Simon P. Fletcher, Oliver E. Amin, Emily J. Colbeck, Laura J. Pallett, William Rosenberg, Hassan Javanbakht, Sophie Lehar, Mala K. Maini, Christian R. Frey, Shahzada Khan, Holly Micolochick Steuer, Dhivya Ramakrishnan, Stephane Daffis, Adam Palazzo
Publikováno v:
Hepatology (Baltimore, Md.)
Background and aims GS-9688 (selgantolimod) is a toll-like receptor 8 agonist in clinical development for the treatment of chronic hepatitis B (CHB). Antiviral activity of GS-9688 has previously been evaluated in vitro in HBV-infected hepatocytes and
Autor:
Ricardo Ramirez, Li Li, William E. Delaney, Stephan Menne, Sarina Ma, Changsuek Yon, Don Kang, Jason Chamberlain, Christian Voitenleitner, William Rowe, Ruth Chu, Dhivya Ramakrishnan, Magdeleine Hung, Manasa Suresh, Divya Pattabiraman, Stephane Daffis, Paul J. Cote, Rex Santos, Bei Li, Simon P. Fletcher, Scott Balsitis, Sandra Spurlock, Mish Michael R, Jim Zheng, Richard L. Mackman
Publikováno v:
Hepatology (Baltimore, Md.)
Background and aims GS-9688 (selgantolimod) is an oral selective small molecule agonist of toll-like receptor 8 in clinical development for the treatment of chronic hepatitis B. In this study, we evaluated the antiviral efficacy of GS-9688 in woodchu
Autor:
Dhivya Ramakrishnan, Vasudarini Sundararajan, Ranjan Chandrasekaran, Shankar Radhakrishnan, Ramusiddharthan Ravichandran, Keerthivarman Rukmangathan
Publikováno v:
Tropical Journal of Ophthalmology and Otolaryngology. 3:1-7
Autor:
Martin Hubálek, Dhivya Ramakrishnan, Rudolf K. F. Beran, Saketh Chemuru, Henry W. Rohrs, Hyock Joo Kwon, Upasana Mehra, Weimei Xing, Iva Pichová, Michael L. Gross, Bruno Marchand, Michal Doležal, Anita Niedziela-Majka, Aleš Zábranský, Simon P. Fletcher
Publikováno v:
Journal of Virology
The structural maintenance of chromosomes 5/6 complex (Smc5/6) is a host restriction factor that suppresses HBV transcription. HBV counters this restriction by expressing HBV X protein (HBx), which redirects a host ubiquitin ligase to target Smc5/6 f