Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dhiraj Bhavsar"'
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 119:96-106
Gene silencing has immense potential in the treatment of cancer. However, enhancement of its efficiency requires the development of specifically targeted and safe carrier systems. Cationic carriers are generally limited by their immunogenicity. Hence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac5d935a7965c3ee98d41be46368443
https://doi.org/10.1016/j.ejpb.2017.06.006
https://doi.org/10.1016/j.ejpb.2017.06.006
Autor:
Narnamangalam R. Jagannathan, Banudevi Sivanantham, Swaminathan Sethuraman, Dhiraj Bhavsar, David Raj Chellappan, Ravi Ranganathan, Uma Sharma, Anuradha Subramanian, L.R. Jaidev, Uma Maheswari Krishnan
Publikováno v:
Acta Biomaterialia. 49:422-433
Theranostics has received considerable attention since both therapy and imaging modalities can be integrated into a single nanocarrier. In this study, fluorescent iron oxide (FIO) nanoparticles and gemcitabine (G) encapsulated poly(lactide-co-glycoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746ec700e5380c6e9a8c0d904376e254
https://doi.org/10.1016/j.actbio.2016.11.053
https://doi.org/10.1016/j.actbio.2016.11.053
Publikováno v:
Drug Delivery. 23:2488-2496
Nano-delivery systems have significantly evolved over the last decade for the treatment of cancer by enabling site-specific delivery and improved bioavailability. The widely investigated nanoparticle systems are biodegradable polyesters, dendrimers,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea451e8fa6574ece1920378cb31635e
https://doi.org/10.3109/10717544.2015.1016193
https://doi.org/10.3109/10717544.2015.1016193
Publikováno v:
Drug delivery. 23(4)
RNA interference (RNAi) technology using short interfering RNA (si-RNA) has shown immense potential in the treatment of cancers through silencing of specific genes. Cationic non-viral vectors employed for gene delivery exhibit toxic effects in normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d39c6fe61741f036c42737d5b76f56
https://pubmed.ncbi.nlm.nih.gov/25417832
https://pubmed.ncbi.nlm.nih.gov/25417832
Autor:
L.R. Jaidev, N. R. Jagannathan, Dhiraj Bhavsar, Uma Maheswari Krishnan, Swaminathan Sethuraman, Uma Sharma
Publikováno v:
Journal of biomaterials science. Polymer edition. 25(11)
Multifunctional nanoparticles are next generation materials that can be simultaneously used for imaging, diagnosis, and delivery of drugs. However, materials intended for cancer diagnosis need to be investigated for its cell uptake, toxicity, and eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9274d90b53222f1222d54c196ebfb27e
https://pubmed.ncbi.nlm.nih.gov/24911385
https://pubmed.ncbi.nlm.nih.gov/24911385
Publikováno v:
Current gene therapy. 12(4)
Gene silencing has emerged as a promising strategy for molecular therapy of various malignant, viral, hereditary and inflammatory disorders. However, its translation from lab to clinic is yet to gain momentum due to the numerous problems that plague
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac94f0c0bda9a64e67e75ebe21bb626
https://pubmed.ncbi.nlm.nih.gov/22856607
https://pubmed.ncbi.nlm.nih.gov/22856607
Autor:
Uma Maheswari Krishnan, Swaminathan Sethuraman, Lakshmi Narashimhan Ramana, Dhiraj Bhavsar, Krishnakumar Subramanian
Publikováno v:
Nano. 10:1550052
Objective: A major limitation in gene delivery applications employing nanocarriers is the inflammatory response elicited when administered in vivo. The mode of complexation of the oligonucleotide with the carrier can alter its interactions with biomo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1897a5799108b69a7b7a99bcd84ec8f6
https://doi.org/10.1142/s1793292015500526
https://doi.org/10.1142/s1793292015500526