Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis

Autor: Dhinakaran Sambandan, Dee N. Dao, Brian C. Weinrick, Catherine Vilchèze, Sudagar S. Gurcha, Anil Ojha, Laurent Kremer, Gurdyal S. Besra, Graham F. Hatfull, William R. Jacobs

Publikováno v: mBio, Vol 4, Iss 3 (2013)

ABSTRACT The chronic nature of tuberculosis (TB), its requirement of long duration of treatment, its ability to evade immune intervention, and its propensity to relapse after drug treatment is discontinued are reminiscent of other chronic, biofilm-as

Externí odkaz: https://doaj.org/article/0e4ca69911e645169334c63c251a3526

Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis

Autor: Sudagar S. Gurcha, Anil K. Ojha, Dee N. Dao, Laurent Kremer, Dhinakaran Sambandan, Catherine Vilchèze, Gurdyal S. Besra, Brian Weinrick, Graham F. Hatfull, William R. Jacobs

Publikováno v: mBio, Vol 4, Iss 3 (2013)
mBio

The chronic nature of tuberculosis (TB), its requirement of long duration of treatment, its ability to evade immune intervention, and its propensity to relapse after drug treatment is discontinued are reminiscent of other chronic, biofilm-associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbee4ef1404e6211ff3298e86bd8f31
https://journals.asm.org/doi/10.1128/mBio.00222-13

Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria

Autor: Laurent Kremer, Yann Guérardel, Graham F. Hatfull, William R. Jacobs, Anthony D. Baughn, Tsungda Hsu, Xavier Trivelli, Anil K. Ojha, Dhinakaran Sambandan, Anuradha Alahari

Publikováno v: Molecular Microbiology
Molecular Microbiology, Wiley, 2008, 69 (1), pp.164-174. ⟨10.1111/j.1365-2958.2008.06274.x⟩
Molecular Microbiology, Wiley, 2008, epub ahead of print. ⟨10.1111/j.1365-2958.2008.06274.x⟩
Molecular Microbiology, 2008, 69 (1), pp.164-174. ⟨10.1111/j.1365-2958.2008.06274.x⟩

International audience; Successful treatment of human tuberculosis requires 6-9 months' therapy with multiple antibiotics. Incomplete clearance of tubercle bacilli frequently results in disease relapse, presumably as a result of reactivation of persi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b336b72226ef6fac77e5348b3e51b3e5
https://pubmed.ncbi.nlm.nih.gov/18466296

Guidance on Noncorticosteroid Systemic Immunomodulatory Therapy in Noninfectious Uveitis: Fundamentals Of Care for UveitiS (FOCUS) Initiative

Autor: Accorinti, Massimo, Acharya, Nisha, Adan, Alfredo, Agrawal, Rupesh, Akkoc, Nurullah, Al Ghamdi, Saed, Al Ghamdi, Turki, Al Saati, Anood, Alsabaani, Nasser, Al-Shamarani, Mohamed, Bachta, Artur, Barisani-Asenbauer, Talin, Beare, Nicholas, Porto, Fernanda Belga Ottoni, Blanco, Ricardo, Yee, Anita Chan Sook, Chandran, Vinod, Chiquet, Christophe, Chng, Hiok Hee, Cimbalas, Andrius, Cimino, Luca, Cordero-Coma, Miguel, Cristobal, Couto, Cuevas, Miguel, Eurico da Fonseca, João, de Boer, Joke, de la Torre, Alejandra, De Schryver, Ilse, Derzko-Dzulynsky, Larissa, Diaz-Valle, David, Merino, Claudia Eugenia Duran, Facsko, Andrea, Figueira, Luis, Fonollosa, Alejandro, Fortin, Eric, Gale, Richard, Galeazzi, Mauro, Garcia, Sandra, Garcia Ruiz de Morales, Jose Maria, Gašperšič, Nataša, Goldstein, Debra, Guedes, Marta, Guex-Crosier, Yan, Gul, Ahmet, Hamam, Rola, Haroon, Muhammad, Hasegawa, Kenichi, Heiligenhaus, Arnd, Hooper, Claire, Hwang, Yih-Shiou, Hwang, De-Kuang, Juanola, Xavier, Kaburaki, Toshikatsu, Kadayifcilar, Sibel, Kempen, John, Kezuka, Takeshi, Kherani, Amin, Kirsimäe, Maarja, Kotaniemi, Kaisu, Kraut, Aleksandra, Kubicka-Trząska, Agnieszka, Kuffova, Lucia, Lightman, Susan, Lim, Lyndell, Lim, Wee Kiak, McCluskey, Peter, McGuire, Mairide, Mirabelli, Pierfrancesco, Miserocchi, Elisabetta, Misiuk-Hojło, Marta, Muccioli, Cristina, Muñoz, Santiago, Murphy, Conor, Murray, Philip I., Nagy, Zoltan, Namba, Kenichi, Neri, Piergiorgio, Nguyen, Quan, O'Gradaigh, Donncha, Omair, Mohammed, Otsa, Kati, Ozyazgan, Yilmaz, Pablo, Franco, Paroli, Maria Pia, Pleyer, Uwe, Poór, Gyula, Proença, Rui, Rabinovitch, Theodore, Read, Russell, Rebrov, Margarita, Recillas-Gispert, Claudia, Rothova, Aniki, Schwartzman, Sergio, Seve, Pascal, Sharma, Srilakshmi, Sims, Joanne, Sohár, Nicolette, Suhler, Eric, Szántó, Sándor, Szepessy, Zsuzsanna, Tappeiner, Christoph, Thorne, Jennifer, Tugal Tutkun, Ilknur, Turno-Kręcicka, Anna, Van Calster, Joachim, van der Horst-Bruinsma, Irene, Vidovič Valentinčič, Nataša, Vitale, Albert, Voorduin Ramos, Stephanie, Vukojevic, Nenad, Wakefield, Denis, Willermain, François, Yalcindag, Nilufer, Yamamoto, Joyce Hisae, Yeh, Stephen, Zemaitiene, Reda, Ziouzina, Olga, Dick, Andrew D., Rosenbaum, James T., Al-Dhibi, Hassan A., Belfort, Rubens, Jr., Brézin, Antoine P., Chee, Soon Phaik, Davis, Janet L., Ramanan, Athimalaipet V., Sonoda, Koh-Hei, Carreño, Ester, Nascimento, Heloisa, Salah, Sawsen, Salek, Sherveen, Siak, Jay, Steeples, Laura

Publikováno v: In Ophthalmology May 2018 125(5):757-773

The power of two: an update on fixed-dose combinations for type 2 diabetes.

Autor: Harris, Stewart B.

Publikováno v: Expert Review of Clinical Pharmacology; Nov2016, Vol. 9 Issue 11, p1453-1462, 10p