Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dheeraj Chitara"'
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:6603-6618
Repurposing of antivirals is an attractive therapeutic option for the treatment of COVID-19. Main protease (Mpro), also called 3 C-like protease (3CLpro) is a key protease of SARS-CoV-2 involved in viral replication, and is a promising drug target fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0686505f34972bd8ba58e7ac0ff0d480
https://doi.org/10.1080/07391102.2021.1891141
https://doi.org/10.1080/07391102.2021.1891141
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 39:6370-6383
RNA interference (RNAi) has been of interest given its role in genetic interference. More significantly, recent studies provided evidence of it being one of the antiviral response mechanisms in humans. Argonaute (Ago) protein plays a central role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e43ce29ca5a5868d23ff757b42eee4
https://doi.org/10.1080/07391102.2020.1800511
https://doi.org/10.1080/07391102.2020.1800511
Publikováno v:
Immunomodulators and Human Health ISBN: 9789811663789
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46405ac575b14fe195d4bfabd5da6411
https://doi.org/10.1007/978-981-16-6379-6_1
https://doi.org/10.1007/978-981-16-6379-6_1
Publikováno v:
Homocysteine Metabolism in Health and Disease ISBN: 9789811668661
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::410483dbea242c77ed8ee634534bc5b6
https://doi.org/10.1007/978-981-16-6867-8_14
https://doi.org/10.1007/978-981-16-6867-8_14
Publikováno v:
Journal of biomolecular structuredynamics. 40(24)
Molecular Dynamics simulations are often used in drug design. However, such simulations do not account for the physiological environment of the receptor; hence overlook its impact on biomolecular interactions. To address this lacuna, we identified th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049509400aebd32ba43d2a58dbf3c581
https://pubmed.ncbi.nlm.nih.gov/34699337
https://pubmed.ncbi.nlm.nih.gov/34699337
Autor:
Dheeraj Chitara, B S Sanjeev
Molecular Dynamics (MD) simulations model motion of molecules in atomistic detail and aid in drug design. While simulations on large systems may require several days to complete, analysis of terabytes of data generated in the process could also be ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544256aac2c6221b10c1f198a2bfad13
Repurposing of antivirals is an attractive therapeutic option for the treatment of COVID-19. Mpro (also called 3CLpro) is a key protease of SARS-CoV-2 involved in viral replication, and is a promising drug target for testing the existing antivirals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b2467181295f97546510e4644a5239
https://doi.org/10.26434/chemrxiv.12857927.v1
https://doi.org/10.26434/chemrxiv.12857927.v1