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pro vyhledávání: '"Dhasarathan Ganesan"'
Autor:
Qian Cai, Dhasarathan Ganesan
Publikováno v:
Neurobiology of Disease, Vol 162, Iss , Pp 105582- (2022)
Neurons are highly polarized and post-mitotic cells with the specific requirements of neurotransmission accompanied by high metabolic demands that create a unique challenge for the maintenance of cellular homeostasis. Thus, neurons rely heavily on au
Externí odkaz:
https://doaj.org/article/4f5fbd27b786482f96a4d8835d89d9b9
Autor:
Dhasarathan Ganesan, Qian Cai
Publikováno v:
Biochem J
Amphisomes are intermediate/hybrid organelles produced through the fusion of endosomes with autophagosomes within cells. Amphisome formation is an essential step during a sequential maturation process of autophagosomes before their ultimate fusion wi
Publikováno v:
Autophagy
Mitochondrial defects are a hallmark of early pathophysiology in Alzheimer's disease, with pathologically phosphorylated tau reported to induce mitochondrial toxicity. Mitophagy constitutes a key pathway in mitochondrial quality control by which dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c816ce771c6bbd07e5b4c19e21a9c51
https://europepmc.org/articles/PMC9225291/
https://europepmc.org/articles/PMC9225291/
Autor:
Dhasarathan Ganesan, Anand Ramaian Santhaseela, Tamilselvan Jayavelu, Sudarshana Rajasekaran, Senthilraja Selvam
Publikováno v:
Cell Stress and Chaperones. 24:343-350
Biotin is an indispensable adipogenic agent, and its ability to coordinate carbohydrate, lipid, and amino acid metabolism sensitizes insulin signaling in adipocytes. This enables the organism to adapt and survive under nutrient stress by synthesis an
Publikováno v:
Cell Stress Chaperones
Structures of cellular organelles are intertwined with their functions that undergo alterations once the organelles are stressed. Since organelle functions are dependent on each other, an organelle-specific stress possibly influences the structure an
Autor:
Dhasarathan Ganesan, Sudarshana Rajasekaran, Tamilselvan Jayavelu, Ramaian Santhaseela Anand, Senthilraja Selvam
Publikováno v:
Nutrition research (New York, N.Y.). 79
Tissue-specific metabolism determines their functions that collectively sense and respond to numerous stress cues to achieve systemic homeostasis. Chronic stress skews such metabolic profiles and leads to failure of organs as evidenced by a bias towa
Autor:
Anand Ramaian Santhaseela, Sudarshana Rajasekaran, Senthilraja Selvam, Tamilselvan Jayavelu, Dhasarathan Ganesan
Publikováno v:
Journal of neurochemistryREFERENCES. 154(5)
Autophagy delays the onset of endoplasmic reticulum (ER) stress by recycling cellular debris. However, the cues that elicit autophagy under the emergence of ER stress and their dysregulation during aging remains obscure. Amino acids, notably branched
Autor:
Ganesan, Dhasarathan, Qian Cai
Publikováno v:
Biochemical Journal; May2021, Vol. 478 Issue 10, p1959-1976, 18p
Publikováno v:
Autophagy; Jun2022, Vol. 18 Issue 6, p1472-1474, 3p
Autor:
Ganesan, Dhasarathan, Ramaian Santhaseela, Anand, Rajasekaran, Sudarshana, Selvam, Senthilraja, Jayavelu, Tamilselvan
Publikováno v:
Journal of Neurochemistry; Sep2020, Vol. 154 Issue 5, p562-575, 14p