Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dhasakumar S. Navaratnam"'
Autor:
Matthew R. Fleming, Maile R. Brown, Jack Kronengold, Yalan Zhang, David P. Jenkins, Gulia Barcia, Rima Nabbout, Anne E. Bausch, Peter Ruth, Robert Lukowski, Dhasakumar S. Navaratnam, Leonard K. Kaczmarek
Publikováno v:
Cell Reports, Vol 16, Iss 9, Pp 2281-2288 (2016)
Human mutations in the cytoplasmic C-terminal domain of Slack sodium-activated potassium (KNa) channels result in childhood epilepsy with severe intellectual disability. Slack currents can be increased by pharmacological activators or by phosphorylat
Externí odkaz:
https://doaj.org/article/2cfbf9c489e94d12aaac50269099564c
Autor:
Yifan Zhang, Iman Moeini-Naghani, JunPing Bai, Joseph Santos-Sacchi, Dhasakumar S. Navaratnam
Publikováno v:
Biology Open, Vol 4, Iss 2, Pp 197-205 (2015)
Prestin is targeted to the lateral wall of outer hair cells (OHCs) where its electromotility is critical for cochlear amplification. Using MDCK cells as a model system for polarized epithelial sorting, we demonstrate that prestin uses tyrosine residu
Externí odkaz:
https://doaj.org/article/e89caefe8c234f5fade26200b96cc2b9
Autor:
Daniela Renedo, Nanthiya Sujijantarat, Joseph Antonios, Andrew Koo, Julian Acosta, Guido J Falcone, Ryan Hebert, Lauren H Sansing, Dhasakumar S Navaratnam, Charles Matouk
Publikováno v:
Stroke. 54
Background: Mechanical thrombectomy (MT) has significantly improved clinical outcomes in acute ischemic stroke. We used single-cell RNA sequencing (scRNA-seq) to describe the landscape of human clots at single cell resolution seeking to provide great
Autor:
Michael C. Stankewich, Jun-Ping Bai, Paul R. Stabach, Saaim Khan, Winston J.T. Tan, Alexei Surguchev, Lei Song, Jon S. Morrow, Joseph Santos-Sacchi, Dhasakumar S. Navaratnam
Publikováno v:
Hearing Research. 423:108564
Reports have proposed a putative role for βV spectrin in outer hair cells (OHCs) of the cochlea. In an ongoing investigation of the role of the cytoskeleton in electromotility, we tested mice with a targeted exon deletion of βV spectrin (Spnb5), an
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1427
We describe a protocol to screen for protein-protein interactions using the Gal-4-based yeast two-hybrid system. In this protocol, we describe serial transformation of bait into an already constructed cDNA library in yeast AH109 cells. We find this m
Publikováno v:
Methods in Molecular Biology ISBN: 9781493936137
We describe a protocol to screen for protein-protein interactions using the Gal-4 based yeast two-hybrid system. In this protocol, we describe serial transformation of bait into an already constructed cDNA library in yeast AH109 cells. We find this m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b0049c67d4c3242e5c362b058e2cb64
https://doi.org/10.1007/978-1-4939-3615-1_6
https://doi.org/10.1007/978-1-4939-3615-1_6
Publikováno v:
Journal of Biological Chemistry. 270:19238-19245
The auditory receptor epithelium is an excellent model system for studying the differential expression of ion channel genes. An inward rectifier potassium current is among those which have been measured in only subsets of chick cochlear hair cells. W
Autor:
Dhasakumar S. Navaratnam
Publikováno v:
Methods in Molecular Biology ISBN: 9781934115626
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39cb9a2e6e9da2db19be19d2b403ef0b
https://doi.org/10.1007/978-1-59745-523-7_15
https://doi.org/10.1007/978-1-59745-523-7_15
Autor:
Dhasakumar S, Navaratnam
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 493
We describe a protocol to screen for protein-protein interactions using the Gal-4 based yeast two-hybrid system. In this protocol, we describe serial transformation of bait into an already constructed cDNA library in yeast AH109 cells. We find this m
Publikováno v:
The Journal of physiology. 560(Pt 1)
Electrical resonance is a mechanism used by birds and many vertebrates to discriminate between frequencies of sound, and occurs when the intrinsic oscillation in the membrane potential of a specific hair cell corresponds to a specific stimulus sound