Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dharmin Rokad"'
Autor:
Emir Malovic, Alyssa Ealy, Cameron Miller, Ahyoung Jang, Phillip J. Hsu, Souvarish Sarkar, Dharmin Rokad, Cody Goeser, Aleah Kristen Hartman, Allen Zhu, Bharathi Palanisamy, Gary Zenitsky, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Chuan He, Anumantha G. Kanthasamy
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110619- (2024)
Summary: As the most abundant glial cells in the central nervous system (CNS), astrocytes dynamically respond to neurotoxic stress, however, the key molecular regulators controlling the inflammatory status of these sentinels during neurotoxic stress
Externí odkaz:
https://doaj.org/article/644b233085804a1086375f92d94ebdfb
Autor:
Neeraj Singh, Vivek Lawana, Jie Luo, Phang Phong, Ahmed Abdalla, Bharathi Palanisamy, Dharmin Rokad, Souvarish Sarkar, Huajun Jin, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy
Publikováno v:
Neurobiology of Disease, Vol 117, Iss , Pp 82-113 (2018)
The organophosphate (OP) pesticide chlorpyrifos (CPF), used in agricultural settings, induces developmental and neurological impairments. Recent studies using in vitro cell culture models have reported CPF exposure to have a positive association with
Externí odkaz:
https://doaj.org/article/68167b49ae1d4a65b55553d94282686f
Autor:
Richard Gordon, Neeraj Singh, Vivek Lawana, Anamitra Ghosh, Dilshan S. Harischandra, Huajun Jin, Colleen Hogan, Souvarish Sarkar, Dharmin Rokad, Nikhil Panicker, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy
Publikováno v:
Neurobiology of Disease, Vol 93, Iss , Pp 96-114 (2016)
Chronic microglial activation has been linked to the progressive degeneration of the nigrostriatal dopaminergic neurons evidenced in Parkinson's disease (PD) pathogenesis. The exact etiology of PD remains poorly understood. Although both oxidative st
Externí odkaz:
https://doaj.org/article/ec3a7ae44df5411d81cc55315cddb58c
Publikováno v:
Curr Environ Health Rep
PURPOSE OF REVIEW: This review provides information regarding how exosomes may contribute to environmental chemical-induced pathogenesis of chronic diseases. In connecting exosome biology to environmental toxicology and disease pathogenesis, we addre
Autor:
Huajun Jin, Hariharan Saminathan, Shivani Ghaisas, Manikandan Samidurai, Nikhil Panicker, Valina L. Dawson, Dharmin Rokad, Tae In Kam, Anumantha G. Kanthasamy, Monica R. Langley, Adhithiya Charli, Dilshan S. Harischandra, Arthi Kanthasamy, Olga Pletnikova, Matthew Neal, Souvarish Sarkar, Ted M. Dawson, Vellareddy Anantharam
Publikováno v:
The Journal of Experimental Medicine
Fyn kinase mediates aggregated α-synuclein (αSyn) uptake as well as αSyn-mediated proinflammatory signaling in microglia, leading to NLRP3 inflammasome activation and neuroinflammation in Parkinson’s disease.
Persistent microglia-mediated n
Persistent microglia-mediated n
Autor:
Jie Luo, Vellareddy Anantharam, Poojya Anantharam, Srikant Rangaraju, Anumantha G. Kanthasamy, Heike Wulff, Dilshan S. Harischandra, Neeraj Kumar Singh, Bharathi N. Palanisamy, Sireesha Manne, Vikrant Singh, Lee-Way Jin, Nikhil Panicker, Hai M. Nguyen, Matthew Neal, Huajun Jin, Muhammet Ay, Dharmin Rokad, Ahmed Abdalla, Souvarish Sarkar, Monica R. Langley, Adhithiya Charli, Emir Malovic, Michelle Gabrielle
Publikováno v:
J Clin Invest
Characterization of the key cellular targets contributing to sustained microglial activation in neurodegenerative diseases, including Parkinson’s disease (PD), and optimal modulation of these targets can provide potential treatments to halt disease
Autor:
Kathleen Ahles, Leticia Priscilla Arantes, Michael Aschner, Kevin N. Baer, Atrayee Banerjee, Frédéric J. Baud, Jason Belden, Joseph R. Bidwell, William K. Boyes, Joseph Paul Bressler, S.C. Brown, Marie Capdevielle, Adhithiya Charli, Guangping Chen, Nancy D. Denslow, Aleksandra Buha Djordjevic, Tammy R. Dugas, Marion Ehrich, Marie Fortin, Allison Franzen, Theresa M. Freudenrich, Randle Gallucci, Robinan Gentry, Duane A. Gill, Scott Glaberman, Tracy Greene, Ramesh C. Gupta, Kirstin Hester, Pascal Houzé, Michael F. Hughes, Anumantha Kanthasamy, S. Karanth, Hyung Sik Kim, James E. Klaunig, Gerwald Koehler, Richard S. Lee, Jing Liu, Lin Liu, Jordi Llorens, Edralin A. Lucas, Lerin Luckett-Chastain, Jie Luo, Marina Lopes Machado, Christopher J. Martyniuk, Lara Maxwell, Matteo Minghetti, Tamara L. Mix, K. Olivier, Stephanie Padilla, Carey N. Pope, Benoît Pouyatos, Jairus Pulczinski, Shashi K Ramaiah, Joshua D. Ramsey, Rudy J. Richardson, Dharmin Rokad, Courtney Roper, Daniel Schlenk, Justin Scott, Timothy J. Shafer, Brenda J. Smith, Félix Alexandre Antunes Soares, Vicki Sutherland, Robyn Leigh Tanguay, Kurt J. Varner, Jarrad R. Wagner, David R. Wallace, D.B. Warheit, Philip Wexler, Berran Yucesoy, Daniele Coradini Zamberlan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85742b4ef3caa72100b748273d3a28b4
https://doi.org/10.1016/b978-0-12-813602-7.00048-x
https://doi.org/10.1016/b978-0-12-813602-7.00048-x
Intracellular signaling plays an important role in the communication process of information flow that coordinates all biological actions within a cell. It normally begins with the binding of a particular extracellular signaling molecule to a specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::724fe8eef68fc6982e309c0a0f646a0e
https://doi.org/10.1016/b978-0-12-813602-7.00007-7
https://doi.org/10.1016/b978-0-12-813602-7.00007-7
Autor:
Vivek Lawana, Neeraj Kumar Singh, Bharathi N. Palanisamy, Dharmin Rokad, Ahmed Abdalla, Jie Luo, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Souvarish Sarkar, Phang Phong, Anumantha G. Kanthasamy
Publikováno v:
Neurobiology of Disease, Vol 117, Iss, Pp 82-113 (2018)
The organophosphate (OP) pesticide chlorpyrifos (CPF), used in agricultural settings, induces developmental and neurological impairments. Recent studies using in vitro cell culture models have reported CPF exposure to have a positive association with