Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dharmendra K. Bhargava"'
Autor:
Dharmendra K. Bhargava, P Yadav, Vihang A. Narkar, Debashish Sahay, Raksha Bhat, Carmine De Angelis, Meghana V. Trivedi, Vikas Yadav, Sahar Yazdanfard, Ahmed Al-rawi, C. Kent Osborne, Lanfang Qin, Xiaoyong Fu, Chad J. Creighton, Sarmistha Nanda, Vidyalakshmi Sethunath, Rachel Schiff
PURPOSE: G protein-coupled receptors (GPCRs) represent the largest family of druggable targets in human genome. Although several GPCRs can cross-talk with the human epidermal growth factor receptors (HERs), the expression and function of most GPCRs r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f707e8f16613b2296e9823e8de198b
http://hdl.handle.net/11588/776667
http://hdl.handle.net/11588/776667
Publikováno v:
Cancer Research. 79:4683-4683
G protein coupled receptors (GPCRs) are the largest family of cell surface receptors with over 800 members. Aberrant activation of GPCRs has been implicated in cancer initiation and development. However, many of GPCRs are overexpressed in cancer cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a34ddd66261db4cc0f97d7d0b779abc9
https://doi.org/10.1158/1538-7445.am2019-4683
https://doi.org/10.1158/1538-7445.am2019-4683
Publikováno v:
Cancer Research. 79:4672-4672
Cancer metastasis is the major cause of tumor mortality and has been attributed in part to the presence of a minority subpopulation of cancer stem cells (CSCs) in the bulk of tumor cells. We showed previously that WDR26, a scaffolding/adaptor protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f434dbce1278d521bdc3e5fb323c6c2
https://doi.org/10.1158/1538-7445.am2019-4672
https://doi.org/10.1158/1538-7445.am2019-4672
Publikováno v:
Journal of Cancer Research Updates. 1:162-172
Enhancer of zeste homolog2 (EZH2), first identified as homolog of the Drosophila enhancer of zeste gene, is histone H3 lysine methyltransferase (H3K27me3), a component of polycomb group proteins (PRC2) that represses the gene expression by modifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::055f41fd18aba5b1ff44438212ca08be
https://doi.org/10.6000/1929-2279.2012.01.02.2
https://doi.org/10.6000/1929-2279.2012.01.02.2
Publikováno v:
Journal of Cancer Science & Therapy.
Age is one of the most important risk factors for human malignancies, including breast cancer. In relation to increase in breast cancer incidence, aging can significantly alter breast cancer biology as defined by validated prognostic and predictive b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5476453a48540f17dbf62b0347cedc09
https://doi.org/10.4172/1948-5956.1000187
https://doi.org/10.4172/1948-5956.1000187
Autor:
Sandip K. Mishra, Pranati Sar, Bandita Rath, Sanjib Chaudhary, Dharmendra K. Bhargava, Debomita Sengupta
Publikováno v:
Cancer Research. 72:4961-4961
Crosstalk between thyroid and estrogen hormones actions have been documented with regard to a variety physiological functions. Both of these hormones regulate transcription of target genes by binding to their nuclear receptors that interact with spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d147fe5ca8e583ee3fa78a56427cabf2
https://doi.org/10.1158/1538-7445.am2012-4961
https://doi.org/10.1158/1538-7445.am2012-4961
Autor:
Sanjib Choudhary, Sandip K. Mishra, Dipti Ranjan, Debomita Sengupta, Dharmendra K. Bhargava, Peter Rosalima
Publikováno v:
Cancer Research. 72:LB-27
ERRβ regulates transcriptional activity of ERα as well as ERβ by modulating BCAS2 expression and leads to FST-mediated induction of nuclear fragmentation in ER-positive MCF-7 breast carcinoma cells Dharmendra K Bhargava*, Debomita Sengupta*, Sanji
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ee2d3e4ce84456a0259ba8f88dce8de
https://doi.org/10.1158/1538-7445.am2012-lb-27
https://doi.org/10.1158/1538-7445.am2012-lb-27