Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Dharmendar Rathore"'
Autor:
Jun Li, William E. Collins, Robert A. Wirtz, Dharmendar Rathore, Altaf Lal, Thomas F. McCutchan
Publikováno v:
Emerging Infectious Diseases, Vol 7, Iss 1, Pp 35-42 (2001)
We examined geographically distinct isolates of Plasmodium vivax and categorized them according to developmental success in Anopheles albimanus. We found that parasites from Central America and Colombia form a group distinct from those of Asia. New W
Externí odkaz:
https://doaj.org/article/16903c71fd684eb182af299cc1d7ddb6
Autor:
Dewal Jani, Rana Nagarkatti, Wandy Beatty, Ross Angel, Carla Slebodnick, John Andersen, Sanjai Kumar, Dharmendar Rathore
Publikováno v:
PLoS Pathogens, Vol 4, Iss 4, p e1000053 (2008)
When malaria parasites infect host red blood cells (RBC) and proteolyze hemoglobin, a unique, albeit poorly understood parasite-specific mechanism, detoxifies released heme into hemozoin (Hz). Here, we report the identification and characterization o
Externí odkaz:
https://doaj.org/article/a688632aec0f42dcb572510f2dc426b2
Autor:
William E. Collins, Thomas F. McCutchan, David A. Fidock, Xin-zhuan Su, Dharmendar Rathore, J. Kevin Baird, David J. Fryauff, Takashi Nomura, Thomas E. Wellems, Jane M. Carlton, Hernando A. del Portillo, John C. Wootton
Chloroquine (CQ)–resistant Plasmodium vivax malaria was first reported 12 years ago, nearly 30 years after the recognition of CQ-resistant P. falciparum. Loss of CQ efficacy now poses a severe problem for the prevention and treatment of both diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2fe8c12d7e4e5c45b8f9674eeb53e75
https://ora.ox.ac.uk/objects/uuid:541ead14-0beb-44df-81c7-9dd9b84c2abe
https://ora.ox.ac.uk/objects/uuid:541ead14-0beb-44df-81c7-9dd9b84c2abe
Publikováno v:
Drug Discovery Today: Therapeutic Strategies. 3:153-158
Malaria parasite degrades hemoglobin and releases toxic heme, which is quickly detoxified by the parasite. Whereas several important antimalarials like artemisinin and chloroquine disrupt this process, the mechanism of heme detoxification is not full
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90d26ab1498dc0dd9486238bc874bcf9
https://doi.org/10.1016/j.ddstr.2006.06.003
https://doi.org/10.1016/j.ddstr.2006.06.003
Autor:
Victoria Majam, Rana Chattopadhyay, Walter R. Weiss, Babita Mahajan, Sanjai Kumar, Rana Nagarkatti, Dewal Jani, Dharmendar Rathore, Hong Zheng
Publikováno v:
Infection and Immunity. 73:5402-5409
Proteins present on the surface of malaria parasites that participate in the process of invasion and adhesion to host cells are considered attractive vaccine targets. Aided by the availability of the partially completed genome sequence of the simian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a44ab6ce430303c44bff99ecc5d0b4
https://doi.org/10.1128/iai.73.9.5402-5409.2005
https://doi.org/10.1128/iai.73.9.5402-5409.2005
Publikováno v:
Genetics. 166:637-640
The fixation of neutral compensatory mutations in a population depends on the effective population size of the species, which can fluctuate dramatically within a few generations, the mutation rate, and the selection intensity associated with the indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8270e595949289f2335a6a47fbb33cfc
https://doi.org/10.1534/genetics.166.1.637
https://doi.org/10.1534/genetics.166.1.637
Publikováno v:
Molecular and Biochemical Parasitology. 133:125-129
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ad35702765ab927169bbf9ab9d7435
https://doi.org/10.1016/j.molbiopara.2003.09.004
https://doi.org/10.1016/j.molbiopara.2003.09.004
Autor:
Robert J. Linhardt, John B. Sacci, Thomas F. McCutchan, Sanjai Kumar, Dharmendar Rathore, Sybil C. Lang Hrstka, Patricia de la Vega
Publikováno v:
Journal of Biological Chemistry. 278:40905-40910
Plasmodium falciparum sporozoites invade liver cells in humans and set the stage for malaria infection. Circumsporozoite protein (CSP), a predominant surface antigen on sporozoite surface, has been associated with the binding and invasion of liver ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22face778330b98a1f02f1bc050b4a24
https://doi.org/10.1074/jbc.m306250200
https://doi.org/10.1074/jbc.m306250200
Autor:
Rana Chattopadhyay, David J. Fryauff, David Haynes, Dharmendar Rathore, Sanjai Kumar, Patricia de la Vega, Hishasi Fujioka, Stephen L. Hoffman, Daniel J. Carucci, Ruobing Wang, Kathleen Moch
Publikováno v:
Journal of Biological Chemistry. 278:25977-25981
The annotated sequence of chromosome 2 of Plasmodium falciparum was examined for genes encoding proteins that may be of interest for vaccine development. We describe here the characterization of a protein with an altered thrombospondin Type I repeat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd085459a9650c08927f89b7f8c0e52
https://doi.org/10.1074/jbc.m300865200
https://doi.org/10.1074/jbc.m300865200
Autor:
Walter R. Weiss, Anita Kumar, Kalpana Gowda, Joao C. Aguiar, William O. Rogers, Sanjai Kumar, Dharmendar Rathore, Stephen L. Hoffman, John A. Tine, Joseph G. Harre, Robert W. Gwadz
Publikováno v:
Infection and Immunity. 70:4329-4335
We tested a cytokine-enhanced, multiantigen, DNA priming and poxvirus boosting vaccine regimen for prevention of malaria in thePlasmodium knowlesi-rhesus macaque model system. Animals were primed with a mixture of DNA plasmids encoding two preerythro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722237f400e9ffa24ad02de2a8141b55
https://doi.org/10.1128/iai.70.8.4329-4335.2002
https://doi.org/10.1128/iai.70.8.4329-4335.2002