Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Dharmasaroja P"'
Publikováno v:
Research in Pharmaceutical Sciences, Vol 19, Iss 1, Pp 105-120 (2024)
Background and purpose: Oxidative stress plays an important role in Alzheimer's disease (AD) pathogenesis. Moringa oleifera leaf (MOL) extract has been shown to have antioxidant activities. Here, we studied the antioxidative and anti-apoptotic effect
Externí odkaz:
https://doaj.org/article/fce13556e2f24d20b41e8a044f5fcc6d
Akademický článek
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Autor:
Praween Lolekha, Pornpatr Dharmasaroja, Nattaphol Uransilp, Puchit Sukphulloprat, Sombat Muengtaweepongsa, Kongkiat Kulkantrakorn
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract The diverse clinical manifestation of essential tremor (ET) has led to the question whether the different phenotypes may affect the clinical outcome and progression. This study aimed to estimate the clinical characteristics and natural histo
Externí odkaz:
https://doaj.org/article/b1bc4328c6404f019a5b54a96ce8771b
Publikováno v:
The Scientific World Journal, Vol 2023 (2023)
The tissue-specific protein eEF1A2 has been linked to the development of neurological disorders. The role of eEF1A2 in the pathogenesis of Parkinson’s disease (PD) has yet to be investigated. The aim of this study was to determine the potential neu
Externí odkaz:
https://doaj.org/article/7211f6f3e72e45278e8d7ab73606dc03
Publikováno v:
Advances in Pharmacological and Pharmaceutical Sciences, Vol 2023 (2023)
Metformin (MET) and rapamycin (RAPA) have been reported to protect against neurodegeneration in cellular and animal models of Parkinson’s disease (PD). MET, which is a first-line drug for type 2 diabetes, and RAPA are known as mTORC1 inhibitors. ME
Externí odkaz:
https://doaj.org/article/98c995f676cf4e50be5690a23bf008ce
Publikováno v:
Cerebrovascular Diseases Extra (2022)
Early assessment and management of patients with mild stroke and transient ischemic attack (TIA) by specialists were recommended. Objectives: To evaluate the outcomes of these patients, and identify the predictive factors of clinical progression, unf
Externí odkaz:
https://doaj.org/article/3f8b8f8ec2bb4da58c5ac2801eeaed3f
Autor:
Pornpatr A. Dharmasaroja, Jintana Assanasen, Sunsanee Pongpakdee, Kankamol Jaisin, Praween Lolekha, Muthita Phanasathit, Laksanun Cheewakriengkrai, Chanisa Chotipanich, Pirada Witoonpanich, Sutisa Pitiyarn, Pongtawat Lertwilaiwittaya, Charungthai Dejthevaporn, Chanin Limwongse, Kammant Phanthumchinda
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 11, Iss 1, Pp 64-70 (2021)
Introduction: Molecular imaging has been developed and validated in Thai patients, comprising a portion of patients in the dementia registry. This should provide a more accurate diagnosis of the etiology of dementia, which was the focus of this study
Externí odkaz:
https://doaj.org/article/c4754b96d88e4afa8d86b6e95df01fc6
Publikováno v:
Stroke Research and Treatment, Vol 2022 (2022)
Background. Poststroke dementia is an important consequence of stroke and warrants early prevention, detection, and management. The objective of the study was to develop a simple clinical risk score for predicting risk of vascular dementia in patient
Externí odkaz:
https://doaj.org/article/5127dc7a13384d63bb339a3747bfef67
Publikováno v:
International Journal of Hematology-Oncology and Stem Cell Research, Vol 15, Iss 4 (2021)
Background The protein kinase B/mammalian target of the rapamycin (Akt/mTOR) pathway is one of the most potent prosurvival signaling cascades that is constitutively active in neuroblastoma. The eukaryotic translation elongation factor-1, alpha-2 (eEF
Externí odkaz:
https://doaj.org/article/f62388a636eb4db9bb2af1d0c576f6a9
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the aggregation of α-synuclein protein and selective death of dopaminergic (DA) neurons in the substantia nigra of the midbrain. Although the molecular pathogenesis of PD is
Externí odkaz:
https://doaj.org/article/257c7418b0d24b9ba45bfa0b0a6f5b05