Zobrazeno 1 - 10
of 527
pro vyhledávání: '"Dharmarajan, Sriram"'
Autor:
Monica Singh, Anannya Dhanwal, Arpita Verma, Linus Augustin, Niti Kumari, Soumyananda Chakraborti, Nisheeth Agarwal, Dharmarajan Sriram, Ruchi Jain Dey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Tuberculosis (TB) continues to be a global health crisis, necessitating urgent interventions to address drug resistance and improve treatment efficacy. In this study, we validate lumazine synthase (RibH), a vital enzyme in the riboflavin bio
Externí odkaz:
https://doaj.org/article/61ea364cc9ed4e7f88d0c931cdc85686
Autor:
Mai S. El-Shoukrofy, Amal Atta, Salwa Fahmy, Dharmarajan Sriram, Michael G. Shehat, Ibrahim M. Labouta, Mona A. Mahran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
New Biginelli adducts were rationalised, via the introduction of selected anti-tubercular (TB) pharmacophores into the dihydropyrimidine (DHPM) ring of deoxythymidine monophosphate (dTMP), the natural substrate of Mycobacterium tuberculosis thymidine
Externí odkaz:
https://doaj.org/article/c8a522259c9d48deaa89756aeec51448
Thiazolotriazoles As Anti-infectives: Design, Synthesis, Biological Evaluation and In Silico Studies
Autor:
Umadevi Kizhakke Purakkel, Ganji Praveena, Valli Y. Madabhushi, Surender Singh Jadav, Reddy Shetty Prakasham, Saiprasad Goud Dasugari Varakala, Dharmarajan Sriram, Ewan W. Blanch, Subashani Maniam
Publikováno v:
ACS Omega, Vol 9, Iss 8, Pp 8846-8861 (2024)
Externí odkaz:
https://doaj.org/article/58f48d5bc24149498da74f34bbe1d38a
Akademický článek
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Autor:
Varakala, Saiprasad Dasugari, Reshma, Rudraraju Srilakshmi, Schnell, Robert, Dharmarajan, Sriram
Publikováno v:
In European Journal of Medicinal Chemistry 15 January 2022 228
Autor:
Vallabhaneni S. Murthy, Yasinalli Tamboli, Vagolu Siva Krishna, Dharmarajan Sriram, Fang Xiong Zhang, Gerald W. Zamponi, Vijayaparthasarathi Vijayakumar
Publikováno v:
ACS Omega, Vol 6, Iss 14, Pp 9731-9740 (2021)
Externí odkaz:
https://doaj.org/article/6f3ef93f05f34839bc75746d608f4911
Autor:
Khan, Mehak Zahoor, Hunt, Debbie M., Singha, Biplab, Kapoor, Yogita, Singh, Nitesh Kumar, Sai Prasad, D. V., Dharmarajan, Sriram, Sowpati, Divya Tej, de Carvalho, Luiz Pedro S., Nandicoori, Vinay Kumar
Publikováno v:
eLife; 8/29/2024, p1-21, 21p
Autor:
Preeti S. Salve, Prajakta Parchure, Lisel Araujo, Rohini S. Kavalapure, Sunil S. Jalalpure, Dharmarajan Sriram, Vagolu Siva Krishna, Madhu Rekha Estharla, Shankar G. Alegaon
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Background Tuberculosis is evidently a major health threat among human populations worldwide. The current study presents the synthesis of new 3-((7-chloroquinolin-4-yl)amino)thiazolidin-4-one analogs (4a–o) as potential Mycobacterium tuber
Externí odkaz:
https://doaj.org/article/3a6e0533143a4486ba50230062ef6e60
Autor:
Srihari Konduri, Dodda Bhargavi, Jyothi Prashanth, Vagolu Siva Krishna, Dharmarajan Sriram, Koya Prabhakara Rao
Publikováno v:
ACS Omega, Vol 6, Iss 2, Pp 1657-1667 (2021)
Externí odkaz:
https://doaj.org/article/162a0b8cdff6409889cc6b4f6d912ba2
Autor:
Vallabhaneni S. Murthy, Yasinalli Tamboli, Vagolu Siva Krishna, Dharmarajan Sriram, Siddique Akber Ansari, Abdullah A. Alarfaj, Abdurahman H. Hirad, Vijayaparthasarathi Vijayakumar
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1751-1759 (2021)
Molecular hybridisation of four bioactive fragments piperazine, substituted-benzofuran, amino acids, and 2,4-dinitrobenzenesulfonamide as single molecular architecture was designed. A series of new hybrids were synthesised and subjected to evaluation
Externí odkaz:
https://doaj.org/article/750a11d6be6b49e2873965aa6c6ec1fa