Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Dharmaraja, Allimuthu"'
Autor:
Sai Kumari Vechalapu, Rakesh Kumar, Niranjan Chatterjee, Sikha Gupta, Shweta Khanna, Pooja Yedehalli Thimmappa, Sathyapriya Senthil, Raju Eerlapally, Manjunath B. Joshi, Santosh K. Misra, Apparao Draksharapu, Dharmaraja Allimuthu
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109899- (2024)
Summary: The emergence of multidrug resistance in cancer cells necessitates the development of new therapeutic modalities. One way cancer cells orchestrate energy metabolism and redox homeostasis is through overloaded iron pools directed by iron regu
Externí odkaz:
https://doaj.org/article/d781dfe94dca4aed83dfa97d20d9a237
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/58b5e85d64544f69b8056045226fc69a
Autor:
Eswar Shankar, Sridhar SNC, Xilal Y. Rima, Prem Kushwaha, Shiv Verma, Gautam K. Sarathy, Anagh kulkarni, Dharmaraja Allimuthu, Eduardo Reátegui, Sanjay Gupta, Bhuvaneswari Ramaswamy
Publikováno v:
Cancer Research. 83:P2-16
Objective: Triple Negative Breast Cancers (TNBC) are highly invasive and 46% of patients develop distant metastases, leading to higher mortality. Chemotherapy remains the most efficacious option, however, there is still a largely unmet need to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::840cd67fddd95234bde2291c3fa11e90
https://doi.org/10.1158/1538-7445.sabcs22-p2-16-05
https://doi.org/10.1158/1538-7445.sabcs22-p2-16-05
Autor:
Tyagi, Priyanka, Dharmaraja, Allimuthu T., Bhaskar, Ashima, Chakrapani, Harinath, Singh, Amit
Publikováno v:
In Free Radical Biology and Medicine July 2015 84:344-354
Autor:
Shreyasi Banik, Pradeep Kumar, Vikas D. Ghule, Shweta Khanna, Dharmaraja Allimuthu, Srinivas Dharavath
Publikováno v:
Journal of Materials Chemistry A. 10:22803-22811
Energetic materials serve as remarkable fuel/propellants for space shuttles, and their utility in civil and military applications is vast.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0fb9f902f60d5f5b04e169cac503ee5
https://doi.org/10.1039/d2ta07372b
https://doi.org/10.1039/d2ta07372b
Autor:
Viral Rawat, Sona Tiwari, Shweta Khanna, Umang Gupta, Sridhar S. N. C., Dharmendra K. Yadav, Grace Kaul, Abdul Akhir, Deepanshi Saxena, Saravanan Matheshwaran, Sidharth Chopra, Dharmaraja Allimuthu
Publikováno v:
Chemical Communications. 58:11669-11672
To target antimicrobial resistance, 4-nitroisobenzofuran-1(3H)-one (IITK2020), is presented as an exclusive inhibitor of S. aureus including drug-resistant S. aureus clinical strains, that prevents peptidoglycan biosynthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339d7d028473716f27d81cd7e5256991
https://doi.org/10.1039/d2cc04102b
https://doi.org/10.1039/d2cc04102b
Publikováno v:
ACS Chemical Biology. 16:1288-1297
Inducing the formation of new oligodendrocytes from oligodendrocyte progenitor cells (OPCs) represents a potential approach to repairing the loss of myelin observed in multiple sclerosis and other diseases. Recently, we demonstrated that accumulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e46aa4e707d3b9f6a781ca327543c4
https://doi.org/10.1021/acschembio.1c00461
https://doi.org/10.1021/acschembio.1c00461
Autor:
Joel L. Sax, Samantha N. Hershman, Zita Hubler, Dharmaraja Allimuthu, Matthew S. Elitt, Ilya Bederman, Drew J. Adams
Regeneration of myelin in the CNS is being pursued as a potential therapeutic approach for multiple sclerosis. Several labs have reported small molecules that promote oligodendrocyte formation and remyelination in vivo. Recently, we reported that man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e56aac94439e508a8ac34538192f20
https://doi.org/10.1101/2022.06.21.497032
https://doi.org/10.1101/2022.06.21.497032
Autor:
Olga Gorelenkova Miller, Kyle S Cole, Corey C Emerson, Dharmaraja Allimuthu, Marcin Golczak, Phoebe L Stewart, Eranthie Weerapana, Drew J Adams, John J Mieyal
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187991 (2017)
Glutaredoxin (Grx1) is a ubiquitously expressed thiol-disulfide oxidoreductase that specifically catalyzes reduction of S-glutathionylated substrates. Grx1 is known to be a key regulator of pro-inflammatory signaling, and Grx1 silencing inhibits infl
Externí odkaz:
https://doaj.org/article/1946c27c3e7a4148add6193db46da8d3
Autor:
William K. Wilson, Matthew S. Elitt, Dharmaraja Allimuthu, Paul J. Tesar, Ilya Bederman, Mayur Madhavan, Franz Bracher, H. Elizabeth Shick, Martin Giera, Joel L. Sax, Jing Jin, Yuriy Fedorov, Eric Garrison, Zita Hubler, Drew J. Adams, Kevin C. Allan, Robert H. Miller, Daniel C. Factor, Matthew A. Thompson, Molly Karl, Zachary S. Nevin
Publikováno v:
Nature, 560(7718), 372
Nature
Nature
Regeneration of myelin is mediated by oligodendrocyte progenitor cells (OPCs), an abundant stem cell population in the CNS and the principal source of new myelinating oligodendrocytes. Loss of myelin-producing oligodendrocytes in the central nervous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bd92c8bbc40fd074b077d070760713
https://doi.org/10.1038/s41586-018-0360-3
https://doi.org/10.1038/s41586-018-0360-3