Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Dharmaraj Chinnappan"'
Autor:
Ivan D. Bochkov, Ashok Cutkosky, Doug McKenna, Adrian L. Sanborn, Su Chen Huang, Kristopher Geeting, Erez Lieberman Aiden, Andreas Gnirke, Neva C. Durand, Alexandre Melnikov, Jian Li, Dharmaraj Chinnappan, Eric S. Lander, Miriam H. Huntley, Andrew I. Jewett, Elena K. Stamenova, Suhas S.P. Rao
Publikováno v:
The FASEB Journal. 30
We recently used in situ Hi-C to create kilobase-resolution 3D maps of mammalian genomes. Here, we combine these maps with new Hi-C, microscopy, and genome-editing experiments to study the physical structure of chromatin fibers, domains, and loops. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::857e746fb9757aadda19b9e672922e63
https://doi.org/10.1096/fasebj.30.1_supplement.588.1
https://doi.org/10.1096/fasebj.30.1_supplement.588.1
Autor:
Mary Levy, Sait Ozturk, Jose F. Ponte, Arunthathi Thiagalingam, Arthur W. Lambert, Sam Thiagalingam, Dharmaraj Chinnappan, Hamid Mostafavi Abdolmaleky, Panagiotis Papageorgis, Fangming Gao, Kuang-hung Cheng, Hongjie Pan
Publikováno v:
Scopus-Elsevier
It has been universally believed that spindle assembly checkpoint (SAC) proteins which include the kinetochore proteins are involved in monitoring the faithful segregation of sister chromatids during cell division and hence defects in these proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e9e2d9c4337365af77dcaedfeea110
https://doi.org/10.4161/cbt.8.7.7928
https://doi.org/10.4161/cbt.8.7.7928
Autor:
Maria Makitalo, Hao G. Nguyen, Katya Ravid, Cynthia St. Hilaire, Dharmaraj Chinnappan, Dan Yang
Publikováno v:
The FASEB Journal. 23:2741-2748
High expression of Aurora-B has been observed in various cancers, and inhibition of this kinase has been shown to halt cellular proliferation. However, the mechanism of effect of Aurora-B on cellular transformation has not been fully explored. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1495d8087c460d7220500292378e58
https://doi.org/10.1096/fj.09-130963
https://doi.org/10.1096/fj.09-130963
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 295:G153-G162
Ectopic expression of the gastrin-releasing peptide (GRP) receptor (GRP-R) occurs frequently in human malignancies of the gastrointestinal tract. Owing to paracrine and autocrine interaction with its specific high-affinity ligand GRP, tumor cell prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc1d8f0ac49bebed597704d9a1eadcd
https://doi.org/10.1152/ajpgi.00036.2008
https://doi.org/10.1152/ajpgi.00036.2008
Autor:
Ivan D. Bochkov, Andreas Gnirke, Alexandre Melnikov, Kristopher Geeting, Ashok Cutkosky, Andrew I. Jewett, Elena K. Stamenova, Adrian L. Sanborn, Miriam H. Huntley, Erez Lieberman Aiden, Jian Li, Suhas S.P. Rao, Su Chen Huang, Doug McKenna, Dharmaraj Chinnappan, Eric S. Lander, Neva C. Durand
Publikováno v:
Proceedings of the National Academy of Sciences. 112
We recently used in situ Hi-C to create kilobase-resolution 3D maps of mammalian genomes. Here, we combine these maps with new Hi-C, microscopy, and genome-editing experiments to study the physical structure of chromatin fibers, domains, and loops. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25b5579fa65c9da578602d797548f8e
https://doi.org/10.1073/pnas.1518552112
https://doi.org/10.1073/pnas.1518552112
Publikováno v:
Cancer Research. 65:9934-9942
Our previous studies indicate that the activation of mitogen-activated protein kinase (MAPK) pathway is involved in bombesin-induced cell proliferation in prostate cancer cells. Cyclin D1 is a critical regulator involved in cell cycle progression thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70cf34f3cdfca4f220beff8dc64fc7e2
https://doi.org/10.1158/0008-5472.can-05-1830
https://doi.org/10.1158/0008-5472.can-05-1830
Publikováno v:
Molecular and Cellular Biology. 25:4977-4992
The kinase Aurora-B, a regulator of chromosome segregation and cytokinesis, is highly expressed in a variety of tumors. During the cell cycle, the level of this protein is tightly controlled, and its deregulated abundance is suspected to contribute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8299de304b97b92333dbf07aa0caa032
https://doi.org/10.1128/mcb.25.12.4977-4992.2005
https://doi.org/10.1128/mcb.25.12.4977-4992.2005
Autor:
Pratima Nemani, David Sidransky, Joseph A. Califano, Jose F. Ponte, Dharmaraj Chinnappan, Arunthathi Thiagalingam, Hongjie Pan, Sam Thiagalingam, Andrea L. Russo, Kuang-hung Cheng
Publikováno v:
Clinical Cancer Research. 11:2466-2470
Promoter DNA methylation status of six genes in samples derived from 27 bronchial epithelial cells and matching blood samples from 22 former/current smokers and five nonsmokers as well as 49 primary non–small cell lung cancer samples with correspon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59b7b503a202398216a2bfbdb9f2e38
https://doi.org/10.1158/1078-0432.ccr-04-1962
https://doi.org/10.1158/1078-0432.ccr-04-1962
Autor:
Ada Koo, Tamara Tchkonia, James L. Kirkland, Tamar Pirtskhalava, Nino Giorgadze, Yourka D. Tchoukalova, Dharmaraj Chinnappan, Iordanes Karagiannides, Michael D. Jensen, Andrew Cartwright, R. Armour Forse, Michael Stevenson
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 288:E267-E277
Fat depots vary in function and size. The preadipocytes that fat cells develop from exhibit distinct regional characteristics that persist in culture. Human abdominal subcutaneous cultured preadipocytes undergo more extensive lipid accumulation, high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc33112a4ddea0be436cf9b220d766d
https://doi.org/10.1152/ajpendo.00265.2004
https://doi.org/10.1152/ajpendo.00265.2004
Publikováno v:
Cancer Genetics and Cytogenetics. 131:104-108
Robertsonian translocations were observed in two leukemia patients. The first case was a patient with chronic lymphocytic leukemia, who was found to have a rare Robertsonian translocation der(14;15)(q10;q10). The second case, a patient with acute mye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b56b0ea1dba19e23e16b8a190db469
https://doi.org/10.1016/s0165-4608(01)00478-2
https://doi.org/10.1016/s0165-4608(01)00478-2