Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Dharani Rao"'
Autor:
Jay M. Janz, David W. Piotrowski, Dharani Rao, Christine Bulawa, Zane Wenzel, Kevin Beaumont, Phil Jeffrey, Jonathan J. Novak, Jayasankar Jasti, Amey Barakat, John E. Murphy, Kelly M. Knee, Reema Jasuja
Publikováno v:
American Journal of Hematology
Autor:
Kevin Beaumont, Dharani Rao, Amey Barakat, David W. Piotrowski, Jay Jasti, Parag Sahasrabudhe, Jeanne S. Chang, Jay M. Janz, Zane Wenzel, Reema Jasuja, Kelly M. Knee, Jatin Narula
Publikováno v:
Blood. 134:207-207
Sickle cell disease (SCD) is a severe genetic disorder caused by a single point mutation on the β-chain of adult hemoglobin (Hb A), β6 Glu→Val (Hb S). In the deoxygenated state Hb S polymerizes, leading to RBC sickling and precipitating all downs