Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Dharam P. Chopra"'
Publikováno v:
Stem Cells and Development. 19:131-142
Recent advances in the biology of stem cells has resulted in significant interest in the development of normal epithelial cell lines from the intestinal mucosa, both to exploit the therapeutic potential of stem cells in tissue regeneration and to dev
Autor:
Jean Michel Bidart, Seema Garde, Tae H. Ji, Arthur T. Porter, Dean G. Tang, Edgar Ben-Josef, Shang-You Yang, Dharam P. Chopra
Publikováno v:
The Journal of Urology. :970-976
Purpose: Understanding growth regulation in hormone-refractory prostate cancer may provide avenues for novel treatment interventions. This study was conducted to characterize the expression of the receptor (FSHR) for follicle-stimulating hormone (FSH
Autor:
Wael Sakr, David J. Grignon, Dharam P. Chopra, Fazlul H. Sarkar, A. P. Joiakim, Patricia A. Mathieu, Isaac J. Powell, Anwar N. Mohamed
Publikováno v:
Journal of Cellular Physiology. 169:269-280
Because of a lack of information of the optimum nutritional requirements, epithelial cells derived from normal human prostate and prostate tumors have been difficult to propagate in vitro, which hinders research in prostate carcinogenesis. In an effo
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 14:254-261
Tumor necrosis factor (TNF) may contribute to the pathogenesis of inflammatory airway disorders via the regulation of inflammatory and cellular immune responses. Shed cell surface TNF receptors can act as soluble TNF binding proteins and modulate TNF
Publikováno v:
Radiation Oncology Investigations. 3:363-367
Autor:
Avarachan P. Joiakim, Dharam P. Chopra
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 8:408-416
Vitamin A and calcium are important regulators of growth and differentiation of epithelial cells and are intimately involved in preneoplastic and neoplastic transformation. It has been proposed that their effects are mediated by autocrine/paracrine p
Publikováno v:
The Anatomical Record. 233:261-269
The tracheal mucosa of the Syrian golden hamster has been extensively employed as a model system for respiratory tract cell renewal, injury, and carcinogenesis. However, baseline cell kinetic data are not available for normal juvenile and adolescent
Autor:
Avarachan P. Joiakim, Dharam P. Chopra
Publikováno v:
Toxicology and Applied Pharmacology. 109:529-537
Squamous metaplasia of tracheal mucosa, putative preneoplastic lesions, involves replacement of normal mucociliary epithelium with epidermoid lesions. Alterations in cell differentiation and neoplasia accompany changes in glycoconjugates at the plasm
Autor:
Avarachan P. Joiakim, Dharam P. Chopra
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 27:223-228
Epidermoid metaplasia in the hamster trachea can be produced by treatment with benzo(a)pyrene (BP) or vitamin A deficiency. To elucidate distinguishing features of the two types of lesions, lectin binding to tissue sections of tracheal explants exhib
Autor:
Dharam P. Chopra, Rodger A. Cooney
Publikováno v:
The Anatomical Record. 229:61-72
Limited studies have described the ultrastructure of trachea of late fetal and neonatal hamsters but the effects of parturition and the onset of breathing on structure have not been discussed. This study describes morphological features of ante- and