Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Dhanya K. Nambiar"'
Autor:
Randolph J. Noelle, J. Louise Lines, Lionel D. Lewis, Robert E. Martell, Thierry Guillaudeux, Sam W. Lee, Kathleen M. Mahoney, Matthew D. Vesely, Jerome Boyd-Kirkup, Dhanya K. Nambiar, Andrew M. Scott
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Immune checkpoints limit the activation of the immune system and serve an important homeostatic function but can also restrict immune responses against tumors. Inhibition of specific immune checkpoint proteins such as the B7:CD28 family members progr
Externí odkaz:
https://doaj.org/article/92a332d632f54d36b90898db8de44de2
Autor:
Li Guan, Dhanya K. Nambiar, Hongbin Cao, Vignesh Viswanathan, Shirley Kwok, Angela B. Hui, Yuan Hou, Rachel Hildebrand, Rie von Eyben, Brittany J. Holmes, Junfei Zhao, Christina S. Kong, Nathan Wamsley, Weiruo Zhang, Michael B. Major, Seung W. Seol, John B. Sunwoo, D. Neil Hayes, Maximilian Diehn, Quynh-Thu Le
Publikováno v:
Cancer Research. 83:861-874
Radiotherapy (RT) is one of the primary treatments of head and neck squamous cell carcinoma (HNSCC), which has a high-risk of locoregional failure (LRF). Presently, there is no reliable predictive biomarker of radioresistance in HNSCC. Here, we found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9495becfd7aaa35c361bde0204da396
https://doi.org/10.1158/0008-5472.can-22-1903
https://doi.org/10.1158/0008-5472.can-22-1903
Autor:
Tariq A. Bhat, Arpit Dheeraj, Dhanya K. Nambiar, Surya Pratap Singh, Dong Sool Yim, Rana P. Singh
Publikováno v:
The Prostate. 83:534-546
We have shown that decursin, a coumarin compound, induces cell cycle arrest and apoptosis in human prostate cancer cells (PCa); however, its molecular mechanisms are largely unexplored. We studied the mechanisms associated with its anticancer activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba8da17d2b3a589c9af334bfd8a0204
https://doi.org/10.1002/pros.24482
https://doi.org/10.1002/pros.24482
Autor:
Hongbin Cao, Qian He, Rie von Eyben, Joshua Bloomstein, Dhanya K Nambiar, Vignesh Viswanathan, Sonya Aggarwal, Shirley Kwok, Rachel Liang, Amanda Jeanette Koong, James S Lewis, Christina Kong, Nan Xiao, Quynh-Thu Le
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229311 (2020)
Glial cell-derived neurotrophic factor (GDNF) is reported to promote the survival of neurons and salivary gland regeneration after radiation damage. This study investigated the effect of GDNF on cell migration, growth, and response to radiation in pr
Externí odkaz:
https://doaj.org/article/51c99b646dd34a418aed18e5b84f01b3
Autor:
Amato J. Giaccia, Quynh-Thu Le, Daniel T. Chang, Monica M. Olcina, Caiyun G. Li, Michael S. Binkley, Deana Colburg, Rie von Eyben, Vignesh Viswanathan, Dhanya K. Nambiar, Quaovi H. Sodji
Proportion of various immune cell type in TME of pancreatic cancer (TGCA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f87d4a67ddafdc13b93189ab0a2ffb7
https://doi.org/10.1158/2767-9764.22545558
https://doi.org/10.1158/2767-9764.22545558
Autor:
Amato J. Giaccia, Quynh-Thu Le, Daniel T. Chang, Monica M. Olcina, Caiyun G. Li, Michael S. Binkley, Deana Colburg, Rie von Eyben, Vignesh Viswanathan, Dhanya K. Nambiar, Quaovi H. Sodji
Supplementary Figure S1: Proportion of total NK cell in the tumor microenvironment of 138 pancreatic cancer patients based on the CIBERSORTx analysis of TCGA. Supplementary Figure S2: Immunohistochemical staining of NK cells (Red circle) using NKp46.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9ce888105d74ea970ff4d26bf0cc22
https://doi.org/10.1158/2767-9764.22545561.v1
https://doi.org/10.1158/2767-9764.22545561.v1
Autor:
Amato J. Giaccia, Quynh-Thu Le, Daniel T. Chang, Monica M. Olcina, Caiyun G. Li, Michael S. Binkley, Deana Colburg, Rie von Eyben, Vignesh Viswanathan, Dhanya K. Nambiar, Quaovi H. Sodji
Pancreatic cancer is one of the deadliest cancers, against which current immunotherapy strategies are not effective. Herein, we analyzed the immune cell composition of the tumor microenvironment of pancreatic cancer samples in The Cancer Genome Atlas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817fa32a8cee2e86b420d75e48cc0531
https://doi.org/10.1158/2767-9764.c.6550977
https://doi.org/10.1158/2767-9764.c.6550977
Supplementary figure 1 shows the effect of silibinin and IR alone and in combination treatment for 48 h for the total cell number and number of colony formation in human prostate cancer 22RV1 cells. The combination treatment did not show any signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46865e552df4458deda8d64fd3b55ad8
https://doi.org/10.1158/1535-7163.22503709.v1
https://doi.org/10.1158/1535-7163.22503709.v1
The table depicts the sequences of the gene primers used for the mRNA expression analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e95d7e33b5209a6736ff2f62e0882ec
https://doi.org/10.1158/1535-7163.22503712.v1
https://doi.org/10.1158/1535-7163.22503712.v1
Autor:
Quynh-Thu Le, Maximilian Diehn, D. Neil Hayes, John B. Sunwoo, Seung W. Seol, Michael B. Major, Weiruo Zhang, Nathan Wamsley, Christina S. Kong, Junfei Zhao, Brittany J. Holmes, Rie von Eyben, Rachel Hildebrand, Yuan Hou, Angela B. Hui, Shirley Kwok, Vignesh Viswanathan, Hongbin Cao, Dhanya K. Nambiar, Li Guan
CB-839 overcomes the Nrf2E79Q-induced radiation resistance through regulating TLR4-mediated cytokine changes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817f35959a413b40e9b631ac1971a5f3
https://doi.org/10.1158/0008-5472.22433457
https://doi.org/10.1158/0008-5472.22433457