Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Dhanaraju Mandalapu"'
Publikováno v:
Synthetic and Systems Biotechnology, Vol 3, Iss 3, Pp 159-162 (2018)
The linaridin antibiotic cypemycin is a ribosomal synthesized and post-translationally modified peptide (RiPP) that possesses potent activity against mouse leukemia cells. This peptide natural product contains an S-[(Z)-2-aminovinyl]-d-cysteine (AviC
Externí odkaz:
https://doaj.org/article/54dcd34bcdff43a5a9bc51302cce743e
Autor:
Deependra K. Singh, Dhanaraju Mandalapu, Sushil Kumar, Pooja Maurya, Shagun Krishna, Subhadra Thakur, Suyash Pant, Mohammad Imran Siddiqi, Vishnu L. Sharma, Dibyendu Banerjee
Publikováno v:
Medicinal Chemistry Research. 32:57-75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ceb237a65979b9dc0ec4facddc62ebf
https://doi.org/10.1007/s00044-022-02983-y
https://doi.org/10.1007/s00044-022-02983-y
Autor:
Deependra Kumar Singh, Dhanaraju Mandalapu, Sushil Kumar, Pooja Maurya, Shagun Krishna, Subhadra Thakur, Suyash Pant, Mohammad Imran Siddiqi, Vishnu Lal Sharma, Dibyendu Banerjee
Human DNA ligase (hLigI) plays an important role in the process of DNA replication and repair, making it an important target for cancer. In our tireless efforts for finding selective inhibitors against hLigI, this article reports the design, synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07ee779f1c9d5aed5459e766a9bd9ef1
https://doi.org/10.21203/rs.3.rs-1654597/v1
https://doi.org/10.21203/rs.3.rs-1654597/v1
Publikováno v:
Natural product reports. 39(5)
Covering: 2012 to 2021Cyclopropane attracts wide interests in the fields of synthetic and pharmaceutical chemistry, and chemical biology because of its unique structural and chemical properties. This structural motif is widespread in natural products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29bc2fe2aa3c63b3f00fce3bc50364d
https://pubmed.ncbi.nlm.nih.gov/34860231
https://pubmed.ncbi.nlm.nih.gov/34860231
Autor:
Deependra K. Singh, Dhanaraju Mandalapu, Sushil Kumar, Pooja Maurya, Shagun Krishna, Subhadra Thakur, Suyash Pant, Mohammad Imran Siddiqi, Vishnu L. Sharma, Dibyendu Banerjee
Publikováno v:
Medicinal Chemistry Research. 32:389-389
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8582e3619db5b083abba22784028d809
https://doi.org/10.1007/s00044-022-03007-5
https://doi.org/10.1007/s00044-022-03007-5
Autor:
Tianlu Mo, Xinjian Ji, Wei Yuan, Dhanaraju Mandalapu, Fangting Wang, Yuting Zhong, Fuyou Li, Qin Chen, Wei Ding, Zixin Deng, Shaoning Yu, Qi Zhang
Publikováno v:
Angewandte Chemie. 131:18969-18973
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a98eec233d2891a17234cb5f39335fc
https://doi.org/10.1002/ange.201908490
https://doi.org/10.1002/ange.201908490
Publikováno v:
Organic & Biomolecular Chemistry. 17:1809-1812
The radical S-adenosylmethionine (SAM) superfamily is currently the largest known enzyme family. These enzymes reductively cleave SAM to produce a highly reactive 5'-deoxyadenosyl (dAdo) radical, which abstracts a hydrogen from the substrate and init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617b55657b84d2a3467b70e0f4dfc982
https://doi.org/10.1039/c8ob02906g
https://doi.org/10.1039/c8ob02906g
Publikováno v:
Angewandte Chemie (International ed. in English). 59(23)
Sulfur-based homolytic substitution (SH reaction) plays an important role in synthetic chemistry, yet whether such a reaction could occur on the positively charged sulfonium compounds remains unknown. In the study of the anaerobic coproporphyrinogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5847abe7fc29ff8a9a0355eb1bf3e5
https://pubmed.ncbi.nlm.nih.gov/32065719
https://pubmed.ncbi.nlm.nih.gov/32065719
Publikováno v:
Biochemistry. 58:36-39
Sulfoxides and sulfones are commonly found in nature as a result of thioether oxidation, whereas only a very few enzymes have been found to metabolize these compounds. Utilizing the strong reduction potential of the [4Fe-4S] cluster of radical S-aden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f4c886ef06b065e0d9c01fd85120ac
https://doi.org/10.1021/acs.biochem.8b00844
https://doi.org/10.1021/acs.biochem.8b00844
Publikováno v:
Angewandte Chemie International Edition. 57:6601-6604
The radical S-adenosylmethionine (SAM) superfamily enzymes cleave SAM reductively to generate a highly reactive 5'-deoxyadenosyl (dAdo) radical, which initiates remarkably diverse reactions. Unlike most radical SAM enzymes, the class C radical SAM me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60886dcb6395ffe84d17086d2aee63ed
https://doi.org/10.1002/anie.201712224
https://doi.org/10.1002/anie.201712224