Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Dhananjay Wagh"'
Autor:
Tian Wang, Angela H. Ling, Sara E. Billings, Davood K. Hosseini, Yona Vaisbuch, Grace S. Kim, Patrick J. Atkinson, Zahra N. Sayyid, Ksenia A. Aaron, Dhananjay Wagh, Nicole Pham, Mirko Scheibinger, Ruiqi Zhou, Akira Ishiyama, Lindsay S. Moore, Peter Santa Maria, Nikolas H. Blevins, Robert K. Jackler, Jennifer C. Alyono, John Kveton, Dhasakumar Navaratnam, Stefan Heller, Ivan A. Lopez, Nicolas Grillet, Taha A. Jan, Alan G. Cheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Mammalian inner ear hair cell loss leads to permanent hearing and balance dysfunction. In contrast to the cochlea, vestibular hair cells of the murine utricle have some regenerative capacity. Whether human utricular hair cells regenerate in
Externí odkaz:
https://doaj.org/article/bbd2c632a6e24a05853cb5f0c56c9d00
Autor:
Michael Januszyk, Michelle Griffin, Shamik Mascharak, Heather E. Talbott, Kellen Chen, Dominic Henn, Amanda F. Spielman, Jennifer B.L. Parker, Norah E. Liang, Asha Cotterell, Nicholas Guardino, Deshka S. Foster, Dhananjay Wagh, John Coller, Geoffrey C. Gurtner, Derrick C. Wan, Michael T. Longaker
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101946- (2023)
Summary: Despite its rapidly increased availability for the study of complex tissue, single-cell RNA sequencing remains prohibitively expensive for large studies. Here, we present a protocol using oligonucleotide barcoding for the tagging and pooling
Externí odkaz:
https://doaj.org/article/2de5342d346f4c9a9e36c09ca4833ca7
Autor:
Michal Caspi Tal, Laughing Bear Torrez Dulgeroff, Lara Myers, Lamin B. Cham, Katrin D. Mayer-Barber, Andrea C. Bohrer, Ehydel Castro, Ying Ying Yiu, Cesar Lopez Angel, Ed Pham, Aaron B. Carmody, Ronald J. Messer, Eric Gars, Jens Kortmann, Maxim Markovic, Michaela Hasenkrug, Karin E. Peterson, Clayton W. Winkler, Tyson A. Woods, Paige Hansen, Sarah Galloway, Dhananjay Wagh, Benjamin J. Fram, Thai Nguyen, Daniel Corey, Raja Sab Kalluru, Niaz Banaei, Jayakumar Rajadas, Denise M. Monack, Aijaz Ahmed, Debashis Sahoo, Mark M. Davis, Jeffrey S. Glenn, Tom Adomati, Karl S. Lang, Irving L. Weissman, Kim J. Hasenkrug
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT It is well understood that the adaptive immune response to infectious agents includes a modulating suppressive component as well as an activating component. We now show that the very early innate response also has an immunosuppressive compon
Externí odkaz:
https://doaj.org/article/d8f71f31b4e248b893caeb967d0cb234
Autor:
Michael Januszyk, Kellen Chen, Dominic Henn, Deshka S. Foster, Mimi R. Borrelli, Clark A. Bonham, Dharshan Sivaraj, Dhananjay Wagh, Michael T. Longaker, Derrick C. Wan, Geoffrey C. Gurtner
Publikováno v:
Micromachines, Vol 11, Iss 9, p 815 (2020)
Background: Recent advances in high-throughput single-cell sequencing technologies have led to their increasingly widespread adoption for clinical applications. However, challenges associated with tissue viability, cell yield, and delayed time-to-cap
Externí odkaz:
https://doaj.org/article/73d09043c38a41819e62c01506a41864
Autor:
Ryan T Terry-Lorenzo, Viviana I Torres, Dhananjay Wagh, Jose Galaz, Selene K Swanson, Laurence Florens, Michael P Washburn, Clarissa L Waites, Eckart D Gundelfinger, Richard J Reimer, Craig C Garner
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167535 (2016)
Synaptic vesicles (SVs) fuse with the plasma membrane at a precise location called the presynaptic active zone (AZ). This fusion is coordinated by proteins embedded within a cytoskeletal matrix assembled at the AZ (CAZ). In the present study, we have
Externí odkaz:
https://doaj.org/article/c98af2f3e56245ee872e4c61b972e3f2
Autor:
Dhananjay Wagh, Ryan Terry-Lorenzo, Clarissa L Waites, Sergio A Leal-Ortiz, Christoph Maas, Richard J Reimer, Craig C Garner
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120093 (2015)
The dynamic assembly of filamentous (F) actin plays essential roles in the assembly of presynaptic boutons, the fusion, mobilization and recycling of synaptic vesicles (SVs), and presynaptic forms of plasticity. However, the molecular mechanisms that
Externí odkaz:
https://doaj.org/article/a3bd617a5a7a4c298d15135015a81ac9
Autor:
Zinaida Good, Jay Y. Spiegel, Bita Sahaf, Meena B. Malipatlolla, Zach J. Ehlinger, Sreevidya Kurra, Moksha H. Desai, Warren D. Reynolds, Anita Wong Lin, Panayiotis Vandris, Fang Wu, Snehit Prabhu, Mark P. Hamilton, John S. Tamaresis, Paul J. Hanson, Shabnum Patel, Steven A. Feldman, Matthew J. Frank, John H. Baird, Lori Muffly, Gursharan K. Claire, Juliana Craig, Katherine A. Kong, Dhananjay Wagh, John Coller, Sean C. Bendall, Robert J. Tibshirani, Sylvia K. Plevritis, David B. Miklos, Crystal L. Mackall
Publikováno v:
Nature Medicine. 28:1860-1871
Publikováno v:
GLOBAL JOURNAL FOR RESEARCH ANALYSIS. :29-31
Introduction: Computerized tomography (CT) is a crucial technique for determining the severity of COVID-19. Ground glass opacities (GGO), crazy-paving patterns, and parenchymal consolidations are the most frequent patterns. Fibrosis, subpleural lines
Autor:
Tian Wang, Angela H. Ling, Sara E. Billings, Davood K. Hosseini, Yona Vaisbuch, Grace S. Kim, Patrick J. Atkinson, Zahra N. Sayyid, Ksenia A. Aaron, Dhananjay Wagh, Nicole Pham, Mirko Scheibinger, Akira Ishiyama, Peter Santa Maria, Nikolas H. Blevins, Robert K. Jackler, Stefan Heller, Ivan A. Lopez, Nicolas Grillet, Taha A. Jan, Alan G. Cheng
Mammalian inner ear hair cell loss leads to permanent hearing and balance dysfunction. In contrast to the cochlea, vestibular hair cells of the murine utricle have some regenerative capacity. Whether human utricular hair cells regenerate remains unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d51fc5ccbf2422a031a62c457d223be
https://doi.org/10.1101/2022.10.29.514378
https://doi.org/10.1101/2022.10.29.514378
Autor:
Zinaida Good, Mark P. Hamilton, Jay Y. Spiegel, Sreevidya Kurra, Moksha H. Desai, Snehit Prabhu, Shin-Heng Chiou, Christine Y. Yeh, Yiyun Chen, Eric Yang, Michael G. Ozawa, Fang Wu, Matthew J. Frank, Lori Muffly, Gursharan K. Claire, Juliana Craig, Maria I. Iglesias, Sushma Bharadwaj, Katherine A. Kong, Dhananjay Wagh, John Coller, Mark M. Davis, Sylvia K. Plevritis, Bita Sahaf, David B. Miklos, Crystal L. Mackall
Publikováno v:
Cancer Research. 83:1128-1128
Autologous T cells genetically engineered to express a chimeric antigen receptor (CAR) targeting CD19 and/or CD22 have achieved high complete response rates in patients with hematologic malignancies, but >50% of patients progress following therapy. H