Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Dhanalakshmi Sivanandhan"'
Autor:
Chandru Gajendran, Shoichi Fukui, Naveen M. Sadhu, Mohammed Zainuddin, Sridharan Rajagopal, Ramachandraiah Gosu, Sarah Gutch, Saeko Fukui, Casey E. Sheehy, Long Chu, Santosh Vishwakarma, D. A. Jeyaraj, Gurulingappa Hallur, Denisa D. Wagner, Dhanalakshmi Sivanandhan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Protein arginine deiminases (PAD) 4 is an enzyme that catalyzes citrullination of protein and its role in autoimmune diseases has been established through clinical genetics and gene knock out studies in mice. Further, studies with PAD4 – d
Externí odkaz:
https://doaj.org/article/6dafa58388074e5abe4049b5154399a4
Autor:
Chandru Gajendran, Subramanyam Janardhan Tantry, Naveen Sadhu M, Zainuddin Mohammed, Purushottam Dewang, Mahanandeesha Hallur, Sreekala Nair, Krishnakumar Vaithilingam, Basavaprabhu Nagayya, Sridharan Rajagopal, Dhanalakshmi Sivanandhan
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0279063 (2023)
Dually targeting the epigenetic proteins lysine specific demethylase 1 (LSD1) and histone deacetylases (HDACs) that play a key role in cancer cells by modulating gene repressor complexes including CoREST will have a profound effect in inhibiting tumo
Externí odkaz:
https://doaj.org/article/f5b9a894f21344f3b3a771a2cac2103a
Autor:
Hui Deng, Cindy Lin, Laura Garcia-Gerique, Shuyu Fu, Zachary Cruz, Erin E. Bonner, Matthew Rosenwasser, Sridharan Rajagopal, M Naveen Sadhu, Chandru Gajendran, Mohd Zainuddin, Ramachandraiah Gosu, Dhanalakshmi Sivanandhan, Miriam A. Shelef, Brian Nam, Dan T. Vogl, Dmitry I. Gabrilovich, Yulia Nefedova
Publikováno v:
Cancer Res
Neutrophils are closely involved in the regulation of tumor progression and formation of premetastatic niches. However, the mechanisms of their involvement and therapeutic regulation of these processes remain elusive. Here, we report a critical role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cad0a5da98cde5fb0d1fd8f49925a4
https://doi.org/10.1158/0008-5472.can-21-4045
https://doi.org/10.1158/0008-5472.can-21-4045
Autor:
Yulia Nefedova, Dmitry I. Gabrilovich, Dan T. Vogl, Brian Nam, Miriam A. Shelef, Dhanalakshmi Sivanandhan, Ramachandraiah Gosu, Mohd Zainuddin, Chandru Gajendran, M Naveen Sadhu, Sridharan Rajagopal, Matthew Rosenwasser, Erin E. Bonner, Zachary Cruz, Shuyu Fu, Laura Garcia-Gerique, Cindy Lin, Hui Deng
Supplementary Figure from A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654950670868fe9eae5db8b5e5f414b1
https://doi.org/10.1158/0008-5472.22431864.v1
https://doi.org/10.1158/0008-5472.22431864.v1
Autor:
Yulia Nefedova, Dmitry I. Gabrilovich, Dan T. Vogl, Brian Nam, Miriam A. Shelef, Dhanalakshmi Sivanandhan, Ramachandraiah Gosu, Mohd Zainuddin, Chandru Gajendran, M Naveen Sadhu, Sridharan Rajagopal, Matthew Rosenwasser, Erin E. Bonner, Zachary Cruz, Shuyu Fu, Laura Garcia-Gerique, Cindy Lin, Hui Deng
Supplementary Data from A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a95db27a943d8b96b37085c3924cde
https://doi.org/10.1158/0008-5472.22431870.v1
https://doi.org/10.1158/0008-5472.22431870.v1
Autor:
Yulia Nefedova, Dmitry I. Gabrilovich, Dan T. Vogl, Brian Nam, Miriam A. Shelef, Dhanalakshmi Sivanandhan, Ramachandraiah Gosu, Mohd Zainuddin, Chandru Gajendran, M Naveen Sadhu, Sridharan Rajagopal, Matthew Rosenwasser, Erin E. Bonner, Zachary Cruz, Shuyu Fu, Laura Garcia-Gerique, Cindy Lin, Hui Deng
Neutrophils are closely involved in the regulation of tumor progression and formation of premetastatic niches. However, the mechanisms of their involvement and therapeutic regulation of these processes remain elusive. Here, we report a critical role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca9d5d586c346659e7c674b4fd0631c
https://doi.org/10.1158/0008-5472.c.6514017
https://doi.org/10.1158/0008-5472.c.6514017
Autor:
Dhanalakshmi Sivanandhan, Sridharan Rajagopal, Chandru Gajendran, Naveen Sadhu M, Mohammed Zainuddin, Ramachandraiah Gosu, Luca Rastelli
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de8857d98b38af4f15e5d78c0f86f32a
https://doi.org/10.1136/jitc-2022-sitc2022.1376
https://doi.org/10.1136/jitc-2022-sitc2022.1376
Autor:
Dhanalakshmi Sivanandhan, Sridharan Rajagopal, Chandru Gajendran, Naveen Sadhu M, Mohammed Zainuddin, Ramachandraiah Gosu, Luca Rastelli
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5870167b01edeb8fcda9b1bad8e3db19
https://doi.org/10.1136/jitc-2022-sitc2022.1386
https://doi.org/10.1136/jitc-2022-sitc2022.1386
Autor:
Dhanalakshmi Sivanandhan, Chandru Gajendran, Naveen Sadhu M, Zainuddin Mohammed, Ramachandraiah Gosu, Divsha Sher, Shahar Mansur, Dinorah Friedmann-Morvinski, Sridharan Rajagopal, Luca Rastelli
Publikováno v:
Cancer Research. 83:6269-6269
Introduction: Protein arginine methyltransferases (PRMTs) transfer a methyl group from the cofactor S-adenosyl-L-methionine (SAM) to the arginine of a substrate protein (1,2). PRMT5 is a type II protein arginine methyltransferase that catalyzes the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfd0e58bb7fe1d79f5623b9dd3ac506e
https://doi.org/10.1158/1538-7445.am2023-6269
https://doi.org/10.1158/1538-7445.am2023-6269
Autor:
Dhanalakshmi Sivanandhan, Sridharan Rajagopal, Chandru Gajendran, Naveen Sadhu, Mohd Zainuddin, Ramachandraiah Gosu, Luca Rastelli
Publikováno v:
Cancer Research. 82:B029-B029
MYC is considered a master regulator of human cancers by modulating the transcription of numerous cancer-related genes. MYC amplification is reported in about 15% of all human cancers and is generally associated with poor prognosis and resistance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ff531fd3a10da9b27ac018d5bc3cc98
https://doi.org/10.1158/1538-7445.cancepi22-b029
https://doi.org/10.1158/1538-7445.cancepi22-b029