Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders.

Autor: Diemar MG; 3Rs Management and Consulting ApS, Kongens Lyngby, Denmark., Vinken M; Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Brussel, Belgium., Teunis M; Innovative Testing in Life Sciences & Chemistry, University of Applied Sciences, Utrecht, The Netherlands., Krul CAM; Innovative Testing in Life Sciences & Chemistry, University of Applied Sciences, Utrecht, The Netherlands., Busquet F; Altertox, Ixelles, Belgium., Zajac JD; Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Brussel, Belgium., Kandarova H; Institute of Experimental Pharmacology and Toxicology, Centre of Experimental Medicine, Slovak Academy of Sciences, Bratislava, Slovakia., Corvi R; European Commission, Joint Research Centre (JRC), Ispra, Italy., Rosso MZ; Angel Consulting S.a.S., Genova, Italy., Kharina A; Angel Consulting S.a.S., Genova, Italy., Bryndum LS; Danish Environmental Protection Agency, Copenhagen, Denmark., Santillo M; Center for Food Safety and Applied Nutrition (CFSAN), US Food and Drug Administration (FDA), Laurel, MD, USA., Bloch D; Department of Pesticides Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany., Kucheryavenko O; Department of Chemicals and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany., Panagiotakos D; SCHEER/EC-Scientific Committee on Health, Environmental and Emerging Risks/European Commission, European Commission, Brussels, Belgium., Rogiers V; Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Brussel, Belgium.; SCCS-Scientific Committee on Consumer Safety, European Commission, Brussels, Belgium., Beekhuijzen M; Charles River Laboratories, 's-Hertogenbosch, The Netherlands., Giusti A; Cosmetics Europe-The Personal Care Association, Brussels, Belgium., Najjar A; Beiersdorf AG, Hamburg, Germany.; International Collaboration on Cosmetics Safety (ICCS), Mt Royal, NJ, USA., Courage C; International Collaboration on Cosmetics Safety (ICCS), Mt Royal, NJ, USA., Koenig T; International Collaboration on Cosmetics Safety (ICCS), Mt Royal, NJ, USA., Kolle S; Experimental Toxicology and Ecology, BASF SE, Ludwigshafen am Rhein, Germany (for CEFIC)., Boonen H; H. Lundbeck, Valby, Denmark., Dhalluin S; L'Oreal, Paris, France., Boberg J; Novo Nordisk, Bagsværd, Denmark., Müller BP; Symrise AG, Holzminden, Germany., Kukic P; Safety & Environmental Assurance Centre, Unilever, Bedfordshire, UK., Ritskes-Hoitinga M; Institute for Risk Assessment Sciences Toxicology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Grasselli E; Department of Earth, Environment, and Life Science, University of Genoa, Genova, Italy.; Interuniversity Center for the Promotion of 3R Principles in Teaching and Research (Centro 3R), Pisa, Italy., Zietek T; Doctors Against Animal Experiments, Cologne, Germany., Stoddart G; PETA Science Consortium International e.V., Stuttgart, Germany., Heusinkveld HJ; Dutch National Institute for Public Health and the Environment, Centre for Health Protection, Bilthoven, The Netherlands., Castell JV; Department of Biochemistry, IIS Hospital La Fe and CIBERHED, University of Valencia, Valencia, Spain., Benfenati E; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Yang H; esqLABS GmbH, Saterland, Germany., Perera S; ProtoQSAR SL, Centro Europeo de Empresas Innovadoras, Paterna, Spain.; Departament de Medicina i Ciències de la Vida, Institut de Biologia Evolutiva (CSIC-UPF), Universitat Pompeu Fabra, Barcelona, Spain., Paini A; esqLABS GmbH, Saterland, Germany., Kramer NI; Toxicology Chair Group, Wageningen University, Wageningen, The Netherlands., Hartung T; Center for Alternatives to Animal Testing Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Janssen M; The Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Fritsche E; IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.; Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.; DNTOX GmbH, Düsseldorf, Germany., Jennen DGJ; Department of Toxicogenomics, GROW School for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Piumatti M; Altertox, Ixelles, Belgium., Rathman J; Molecular Networks GMBH Computerchemie, Nuremberg, Germany., Marusczyk J; Molecular Networks GMBH Computerchemie, Nuremberg, Germany., Milec L; Institute of Experimental Pharmacology and Toxicology, Centre of Experimental Medicine, Slovak Academy of Sciences, Bratislava, Slovakia., Roggen EL; 3Rs Management and Consulting ApS, Kongens Lyngby, Denmark.

Publikováno v: Alternatives to laboratory animals : ATLA [Altern Lab Anim] 2024 Mar; Vol. 52 (2), pp. 117-131. Date of Electronic Publication: 2024 Jan 18.

Selection of cytotoxicity markers for the screening of new chemical entities in a pharmaceutical context: A preliminary study using a multiplexing approach

Autor: Gerets, H.H.J., Hanon, E., Cornet, M., Dhalluin, S., Depelchin, O., Canning, M., Atienzar, F.A.

Publikováno v: In Toxicology in Vitro 2009 23(2):319-332

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Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins.

Autor: Gerets, H., Tilmant, K., Gerin, B., Chanteux, H., Depelchin, B., Dhalluin, S., Atienzar, F.

Publikováno v: Cell Biology & Toxicology; Apr2012, Vol. 28 Issue 2, p69-87, 19p, 6 Charts, 2 Graphs

In Vitro Human Liver Model for Toxicity Assessment with Clinical and Preclinical Instrumentation.

Autor: Madorran, Eneko¹ (AUTHOR) eneko.madorran@um.si, Kocbek Šaherl, Lidija¹ (AUTHOR), Rakuša, Mateja¹ (AUTHOR), Munda, Miha¹ (AUTHOR)

Publikováno v: Pharmaceutics. May2024, Vol. 16 Issue 5, p607. 15p.