Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids.

Autor: Dhaliwal NK; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada., Weng OY; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Program in Neurosciences and Mental Health, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Physiology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Dong X; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; The Children's Hospital, National Clinical Research Center for Child Health, School of Medicine, Zhejiang University, Hangzhou 310052, China; The Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou 310029, China., Bhattacharya A; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Ahmed M; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada., Nishimura H; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Choi WWY; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada; Program in Genetics and Genome Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada., Aggarwal A; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Luikart BW; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA., Shu Q; The Children's Hospital, National Clinical Research Center for Child Health, School of Medicine, Zhejiang University, Hangzhou 310052, China., Li X; The Children's Hospital, National Clinical Research Center for Child Health, School of Medicine, Zhejiang University, Hangzhou 310052, China; The Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou 310029, China., Wilson MD; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada; Program in Genetics and Genome Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada., Moffat J; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada; Program in Genetics and Genome Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada., Wang LY; Program in Neurosciences and Mental Health, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Physiology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Muffat J; Program in Neurosciences and Mental Health, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Li Y; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada. Electronic address: yun.li@sickkids.ca.

Publikováno v: Cell reports [Cell Rep] 2024 May 28; Vol. 43 (5), pp. 114173. Date of Electronic Publication: 2024 May 02.

SnapHiC-G: identifying long-range enhancer–promoter interactions from single-cell Hi-C data via a global background model.

Autor: Liu, Weifang¹ (AUTHOR), Zhong, Wujuan² (AUTHOR), Giusti-Rodríguez, Paola³ (AUTHOR), Jiang, Zhiyun⁴ (AUTHOR), Wang, Geoffery W¹ (AUTHOR), Sun, Huaigu⁴ (AUTHOR), Hu, Ming⁵ (AUTHOR) hum@ccf.org, Li, Yun^1,4,6 (AUTHOR) hum@ccf.org

Publikováno v: Briefings in Bioinformatics. Sep2024, Vol. 25 Issue 5, p1-14. 14p.

KLF4 protein stability regulated by interaction with pluripotency transcription factors overrides transcriptional control.

Autor: Dhaliwal NK; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontaria M5S3G5, Canada., Abatti LE; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontaria M5S3G5, Canada., Mitchell JA; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontaria M5S3G5, Canada.

Publikováno v: Genes & development [Genes Dev] 2019 Aug 01; Vol. 33 (15-16), pp. 1069-1082. Date of Electronic Publication: 2019 Jun 20.

The Role of Bee Products in the Control of Antimicrobial Resistance and Biofilm Formation.

Autor: ACAROZ, Ulas^1,2,3 ulasacaroz@hotmail.com, KUREK-GORECKA, Anna⁴, OLCZYK, Paweł⁴, TAS, Nuri¹, ALI, Ahmad⁵, PARAMANYA, Additiya⁵, BALYAN, Prairna⁵, NOOR, Ayesha⁶, KAMARAJ, Sahana⁶, MALEKIFARD, Farnaz⁷, HOSSEINI, Arnoosh⁷, ISTANBULLUGIL, Fatih Ramazan³, ARSLAN-ACAROZ, Damla^2,8,9, ASMA, Syeda Tasmia¹, SEGUENI, Narimane^10,11, CEYLAN, Ahmet Bahattin¹², Xiaolu JIN¹³

Publikováno v: Kafkas Universitesi Veteriner Fakultesi Dergisi. Mar/Apr2024, Vol. 30 Issue 2, p131-153. 23p.

Chromatin Dynamics in Lineage Commitment and Cellular Reprogramming.

Autor: Shchuka VM; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada. virlana.shchuka@mail.utoronto.ca., Malek-Gilani N; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada. neil.macpherson@utoronto.ca., Singh G; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada. gur.singh@mail.utoronto.ca., Langroudi L; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada. lida.langroudi@mail.utoronto.ca., Dhaliwal NK; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada. navroop.dhaliwal@mail.utoronto.ca., Moorthy SD; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada. sakthi.moorthy@utoronto.ca., Davidson S; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada. s.davidson@utoronto.ca., Macpherson NN; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada. neil.macpherson@utoronto.ca., Mitchell JA; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada. ja.mitchell@utoronto.ca.

Publikováno v: Genes [Genes (Basel)] 2015 Jul 17; Vol. 6 (3), pp. 641-61. Date of Electronic Publication: 2015 Jul 17.