'Stem cell' origin of the hematopoietic defect in dyskeratosis congenita

Autor: JC Marsh, AJ Will, JM Hows, P Sartori, PJ Darbyshire, PJ Williamson, DG Oscier, TM Dexter, NG Testa

Publikováno v: Blood. 79(12)

We have used the long-term bone marrow culture (LTBMC) system to analyze hematopoiesis in three patients with dyskeratosis congenita (DC), two of whom had aplastic anemia, and the third had a normal blood count (apart from mild macrocytosis) and norm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dceb7433ed7c0e545ce134c8f5c869a9
https://pubmed.ncbi.nlm.nih.gov/1596563

Immunoglobulin V genes and CD38 expression in CLL

Autor: Tj, Hamblin, Ja, Orchard, Gardiner A, Dg, Oscier, Davis Z, Freda Stevenson

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e856e86f7cb1e6dd1ab349c63728abf0
http://europepmc.org/abstract/med/10787241

Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia

Autor: Tj, Hamblin, Davis Z, Gardiner A, Dg, Oscier, Freda Stevenson

Publikováno v: Scopus-Elsevier
Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::88ed121d5419eefc7a3a958cdd626f17
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033567907&partnerID=MN8TOARS

Telomere length and DNA methylation epitype both provide independent prognostic information in CLL patients; data from the UK CLL4, ARCTIC and ADMIRE clinical trials.

Autor: Carr L; Cancer Genomics, School of Cancer Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Norris K; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, UK., Parker H; Cancer Genomics, School of Cancer Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Nilsson-Takeuchi A; Cancer Genomics, School of Cancer Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Bryant D; Cancer Genomics, School of Cancer Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Amarasinghe H; Cancer Genomics, School of Cancer Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Kadalayil L; Faculty of Engineering and Physical Sciences, School of Chemistry, University of Southampton, Southampton, UK., Else M; Division of Molecular Pathology, The Institute of Cancer Research, London, UK., Pettitt A; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK., Hillmen P; Section of Experimental Haematology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Schuh A; Oxford National Institute for Health Research Biomedical Research Centre/Molecular Diagnostic Centre, University of Oxford, Oxford, UK., Walewska R; Division of Haematology, University Hospitals Dorset, Bournemouth, UK., Baird DM; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, UK., Oscier DG; Division of Haematology, University Hospitals Dorset, Bournemouth, UK., Oakes CC; Division of Haematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA., Gibson J; Cancer Genomics, School of Cancer Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Pepper C; Brighton and Sussex Medical School, University of Sussex, Brighton, UK., Strefford JC; Cancer Genomics, School of Cancer Sciences, University of Southampton, Southampton General Hospital, Southampton, UK.

Publikováno v: British journal of haematology [Br J Haematol] 2024 Nov; Vol. 205 (5), pp. 2072-2076. Date of Electronic Publication: 2024 Sep 10.

Genetic and phenotypic attributes of splenic marginal zone lymphoma.

Autor: Bonfiglio F; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Bruscaggin A; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Guidetti F; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Terzi di Bergamo L; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Faderl M; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Spina V; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Condoluci A; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland.; Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland., Bonomini L; International Extranodal Lymphoma Study Group, Bellinzona, Switzerland., Forestieri G; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Koch R; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Piffaretti D; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Pini K; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Pirosa MC; Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland., Cittone MG; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland.; Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland., Arribas A; Lymphoma Genomics, Institute of Oncology Research, Bellinzona, Switzerland., Lucioni M; Unit of Anatomic Pathology, Department of Molecular Medicine, Fondazione IRCCS Policlinico San Matteo and Università degli Studi di Pavia, Pavia, Italy., Ghilardi G; Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland., Wu W; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland., Arcaini L; Division of Hematology, Fondazione IRCCS Policlinico San Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy., Baptista MJ; Lymphoid Neoplasms Group, Josep Carreras Leukaemia Research Institute, Badalona, Spain., Bastidas G; Division of Hematology, Hospital Clínic i Provincial de Barcelona, Barcelona, Spain., Bea S; Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS).; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) 28029, Madrid, Spain.; Pathology Department, Hospital Clínic, Barcelona University, Barcelona, Spain., Boldorini R; Division of Pathology, University of Eastern Piedmont, Novara, Italy., Broccoli A; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia Seràgnoli, Bologna, Italy., Buehler MM; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Canzonieri V; Pathology Unit, CRO Aviano National Cancer Institute, Aviano, Italy.; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Cascione L; Lymphoma Genomics, Institute of Oncology Research, Bellinzona, Switzerland., Ceriani L; Clinic of Nuclear Medicine and PET-CT Centre, Imaging Institute of Southern Switzerland, Bellinzona, Switzerland., Cogliatti S; Institute of Pathology, Kantonsspital St Gallen, St Gallen, Switzerland., Corradini P; Division of Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Derenzini E; Onco-hematology Division, European Institute of Oncology (IEO) IRCCS, Milan, Italy., Devizzi L; Division of Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Dietrich S; Division of Hematology, University Hospital Heidelberg, Heidelberg, Germany., Elia AR; Cancer Immunotherapy, Institute of Oncology Research, Bellinzona, Switzerland., Facchetti F; Department of Molecular and Translational Medicine, Pathology Unit, Spedali Civili, Brescia, Italy., Gaidano G; Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy., Garcia JF; Division of Pathology, MD Anderson Cancer Center, Madrid, Spain., Gerber B; Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.; Department of Hematology and Oncology, University of Zurich, Zurich, Switzerland., Ghia P; Strategic Research Program on Chronic Lymphocytic Leukemia (CLL), IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milan, Italy., Gomes da Silva M; Division of Hematology, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal., Gritti G; Division of Hematology, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Guidetti A; Division of Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Hitz F; Division of Hematology, Kantonsspital St Gallen, St Gallen, Switzerland., Inghirami G; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY., Ladetto M; Division of Hematology, Azienda Ospedaliera SS Antonio e Biagio, Alessandria, Italy.; Dipartimento di Medicina Traslazionale, University of Eastern Piedmont, Alessandria, Italy., Lopez-Guillermo A; Division of Lymphoid Neoplasms, Hospital Clínic i Provincial de Barcelona, Barcelona, Spain., Lucchini E; Division of Hematology, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy., Maiorana A; Division of Pathology, Universitá degli Studi di Modena e Reggio Emilia, Modena, Italy., Marasca R; Hematology Unit, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy., Matutes E; Haematopathology Unit, Hospital Clínic i Provincial de Barcelona, Barcelona, Spain., Meignin V; Division of Pathology, Saint Louis Hospital, Paris, France., Merli M; Division of Hematology, University of Insubria and ASST Sette Laghi, Ospedale di Circolo of Varese, Varese, Italy., Moccia A; Clinic of Medical Oncology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland., Mollejo M; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) 28029, Madrid, Spain.; Division of Pathology, Hospital Virgen de la Salud, Toledo, Spain., Montalban C; Division of Hematology, MD Anderson Cancer Center, Madrid, Spain., Novak U; Department of Medical Oncology and University Cancer Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Oscier DG; Division of Hematology, University Hospitals Dorset, Bournemouth, United Kingdom., Passamonti F; Department of Medicine and Surgery, University of Insubria and ASST Sette Laghi, Ospedale di Circolo of Varese, Varese, Italy., Piazza F; Division of Hematology, Ospedale Universitario di Padova, Padova, Italy., Pizzolitto S; Division of Pathology, General Hospital S Maria della Misericordia, Udine, Italy., Rambaldi A; Division of Hematology, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Sabattini E; Haematopathology Unit, Department of Experimental Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy., Salles G; Faculté de Médecine et de Maïeutique Lyon Sud, Université de Lyon, Lyon, France., Santambrogio E; Candiolo Cancer Institute (FPO-IRCCS), Candiolo, Turin, Italy., Scarfò L; Strategic Research Program on Chronic Lymphocytic Leukemia (CLL), IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milan, Italy., Stathis A; Clinic of Medical Oncology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland., Stüssi G; Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano, Switzerland., Geyer JT; Division of Anatomic Pathology and Clinical Pathology, Weill Cornell Medical College, New York, NY., Tapia G; Division of Pathology, Hospital Germans Trias I Pujol, Universitat Autònoma de Barcelona, Barcelona, Spain., Tarella C; Onco-hematology Division, European Institute of Oncology (IEO) IRCCS, Milan, Italy., Thieblemont C; Assistance Publique-Hôpitaux de Paris, Hopital Saint-Louis, Hemato-Oncology Unit; Université de Paris, Paris, France., Tousseyn T; Department of Haematology, University Hospitals Leuven, Leuven, Belgium., Tucci A; Division of Hematology, Spedali Civili, Brescia, Italy., Vanini G; Department of Medical Oncology and University Cancer Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Visco C; Department of Medicine, Section of Hematology, University of Verona, Italy., Vitolo U; Candiolo Cancer Institute (FPO-IRCCS), Candiolo, Turin, Italy., Walewska R; Division of Hematology, University Hospitals Dorset, Bournemouth, United Kingdom., Zaja F; Division of Hematology, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy., Zenz T; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Zinzani PL; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia Seràgnoli, Bologna, Italy.; Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università di Bologna, Bologna, Italy., Khiabanian H; Center for Systems and Computational Biology, Rutgers University, New Brunswick, NJ., Calcinotto A; Cancer Immunotherapy, Institute of Oncology Research, Bellinzona, Switzerland., Bertoni F; Lymphoma Genomics, Institute of Oncology Research, Bellinzona, Switzerland.; Clinic of Medical Oncology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano, Switzerland., Bhagat G; Department of Pathology and Cell Biology, Columbia University, New York, NY., Campo E; Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS).; Pathology Department, Hospital Clínic, Barcelona University, Barcelona, Spain., De Leval L; Division of Pathology, Institut Universitaire de Pathologie, Lausanne, Switzerland., Dirnhofer S; Institute of Pathology and Medical Genetics, University Hospital Basel, Basel, Switzerland., Pileri SA; Haematopathology Division, European Institute of Oncology IRCCS, Milan, Italy., Piris MA; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) 28029, Madrid, Spain.; Pathology Service, Fundación Jiménez Díaz, Madrid, Spain., Traverse-Glehen A; Division of Pathology, Centre Hospitalier Lyon Sud, Lyon, France., Tzankov A; Institute of Pathology and Medical Genetics, University Hospital Basel, Basel, Switzerland., Paulli M; Unit of Anatomic Pathology, Department of Molecular Medicine, Fondazione IRCCS Policlinico San Matteo and Università degli Studi di Pavia, Pavia, Italy., Ponzoni M; Ateneo Vita-Salute San Raffaele University and Pathology Unit San Raffaele Scientific Institute, Milan, Italy., Mazzucchelli L; Division of Pathology, Cantonal Institute of Pathology, Locarno, Switzerland., Cavalli F; Institute of Oncology Research, Bellinzona, Switzerland; and., Zucca E; International Extranodal Lymphoma Study Group, Bellinzona, Switzerland.; Clinic of Medical Oncology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano, Switzerland.; Department of Medical Oncology, Bern University Hospital and University of Bern, Bern, Switzerland., Rossi D; Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland.; Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano, Switzerland.

Publikováno v: Blood [Blood] 2022 Feb 03; Vol. 139 (5), pp. 732-747.