Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Df, Tough"'
Autor:
Belardelli F, Ferrantini M, Stefano Maria Santini, Baccarini S, Proietti E, Mp, Colombo, Sprent J, Df, Tough
Publikováno v:
Europe PubMed Central
The tumorigenicity of transplantable tumor cells in mice is reduced by transduction with cytokine genes, including IFN-alpha and interleukin (IL) 12. Although T cells are considered important in tumor rejection, the mechanism by which genetically mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c9cd45647ce3adf6df0ba47b1df73dde
https://pubmed.ncbi.nlm.nih.gov/9865738
https://pubmed.ncbi.nlm.nih.gov/9865738
Autor:
Picavet LW; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Samat AAK; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Calis J; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Nijhuis L; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Scholman R; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Mokry M; Department of Experimental Cardiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Tough DF; Immunology Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., Prinjha RK; Immunology Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., Vastert SJ; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.; Department of Pediatric Rheumatology and Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., van Loosdregt J; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Publikováno v:
Biomedicines [Biomedicines] 2024 Jun 18; Vol. 12 (6). Date of Electronic Publication: 2024 Jun 18.
Autor:
Ghiboub M; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology, Endocrinology Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 BK Amsterdam, The Netherlands.; Immunology Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., Bell M; Immunology Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., Sinkeviciute D; Immunology Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., Prinjha RK; Immunology Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., de Winther MPJ; Department of Medical Biochemistry, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Department of Medicine, Institute for Cardiovascular Prevention (IPEK), 80336 Munich, Germany., Harker NR; Immunology Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., Tough DF; Immunology Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., de Jonge WJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology, Endocrinology Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 BK Amsterdam, The Netherlands.; Department of Surgery, University of Bonn, 53127 Bonn, Germany.
Publikováno v:
Current issues in molecular biology [Curr Issues Mol Biol] 2023 May 11; Vol. 45 (5), pp. 4228-4245. Date of Electronic Publication: 2023 May 11.
Autor:
Tough DF; Immunology Research Unit, GSK, Medicines Research Centre, Stevenage, Hertfordshire, UK., Lombardi G; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.
Publikováno v:
Clinical and experimental immunology [Clin Exp Immunol] 2023 Mar 16; Vol. 211 (2), pp. 93-95.
Autor:
Furze RC; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Molnar J; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK.; Galapagos, Cambridge, UK., Parr NJ; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK.; MoonFire Consultancy Ltd, Hertfordshire, UK., Ahmad F; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK.; Galderma R&D, Fort Worth, TX, USA., Henry Y; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK.; YMH-Management Ltd, Lancashire, UK., Howe D; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK.; SoseiHeptares, Cambridge, UK., Singh R; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK.; GlaxoSmithKline, Collegeville, PA, USA., Toal M; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK.; Conan Biopharma Consulting, Wokingham, UK., Bassil AK; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Bernard SG; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Davis RP; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Gibson A; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Maller NC; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Sharp C; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Tough DF; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Prinjha RK; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Lewis HD; Research & Development, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Publikováno v:
British journal of clinical pharmacology [Br J Clin Pharmacol] 2022 Dec; Vol. 88 (12), pp. 5238-5256. Date of Electronic Publication: 2022 Jul 11.
Autor:
Ghiboub M; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.; Immuno-Epigenetics, Adaptive Immunity Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.; Department of Pediatrics, Division of Pediatric Gastroenterology & Nutrition, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Koster J; Department of Oncogenomics, Amsterdam University Medical Centers, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, the Netherlands., Craggs PD; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Li Yim AYF; Immuno-Epigenetics, Adaptive Immunity Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.; Department of Clinical Genetics, Genome Diagnostics Laboratory, Amsterdam Reproduction & Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Shillings A; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Hutchinson S; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Bingham RP; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Gatfield K; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Hageman IL; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Yao G; GlaxoSmithKline, Cambridge, MA, USA., O'Keefe HP; GlaxoSmithKline, Cambridge, MA, USA., Coffin A; Constellation Pharmaceuticals, Cambridge, MA, USA., Patel A; WuXi AppTec, Cambridge, MA, USA., Sloan LA; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Mitchell DJ; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Hayhow TG; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Lunven L; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Watson RJ; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Blunt CE; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Harrison LA; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Bruton G; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Kumar U; Immunology Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK., Hamer N; Immuno-Epigenetics, Adaptive Immunity Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK., Spaull JR; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Zwijnenburg DA; Department of Oncogenomics, Amsterdam University Medical Centers, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, the Netherlands., Welting O; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Hakvoort TBM; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Te Velde AA; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., van Limbergen J; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.; Department of Pediatrics, Division of Pediatric Gastroenterology & Nutrition, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Henneman P; Department of Clinical Genetics, Genome Diagnostics Laboratory, Amsterdam Reproduction & Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Prinjha RK; Immunology Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK., de Winther MPJ; Department of Medical Biochemistry, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.; Institute for Cardiovascular Prevention (IPEK), Munich, Germany., Harker NR; Immunology Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK., Tough DF; Immunology Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK. david.f.tough@gsk.com., de Jonge WJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. w.j.dejonge@amsterdamumc.nl.; Department of Surgery, University of Bonn, Bonn, Germany. w.j.dejonge@amsterdamumc.nl.
Publikováno v:
BMC biology [BMC Biol] 2022 Aug 19; Vol. 20 (1), pp. 182. Date of Electronic Publication: 2022 Aug 19.
Autor:
Soskic B; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Open Targets, Wellcome Genome Campus, Cambridge, UK., Cano-Gamez E; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Open Targets, Wellcome Genome Campus, Cambridge, UK., Smyth DJ; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Ambridge K; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Ke Z; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Matte JC; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Bossini-Castillo L; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Kaplanis J; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Open Targets, Wellcome Genome Campus, Cambridge, UK., Ramirez-Navarro L; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Lorenc A; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Nakic N; GSK, R&D, Stevenage, UK., Esparza-Gordillo J; GSK, R&D, Stevenage, UK., Rowan W; GSK, R&D, Stevenage, UK., Wille D; GSK, R&D, Stevenage, UK., Tough DF; GSK, R&D, Stevenage, UK., Bronson PG; R&D Translational Biology, Biogen, Cambridge, MA, USA., Trynka G; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. gosia@sanger.ac.uk.; Open Targets, Wellcome Genome Campus, Cambridge, UK. gosia@sanger.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2022 Jun; Vol. 54 (6), pp. 817-826. Date of Electronic Publication: 2022 May 26.
Autor:
Alsinet C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. ca6@sanger.ac.uk.; Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. ca6@sanger.ac.uk., Primo MN; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.; Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Lorenzi V; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Bello E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.; Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Kelava I; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Jones CP; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Vilarrasa-Blasi R; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Sancho-Serra C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Knights AJ; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Park JE; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Korea., Wyspianska BS; Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.; Immunology Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage, SG1 2NY, UK., Trynka G; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.; Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Tough DF; Immunology Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage, SG1 2NY, UK., Bassett A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.; Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Gaffney DJ; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. dg13@sanger.ac.uk., Alvarez-Errico D; Josep Carreras Leukaemia Research Institute (IJC), Badalona, 08916, Barcelona, Catalonia, Spain. dalvarez@carrerasresearch.org., Vento-Tormo R; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. rv4@sanger.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2022 May 24; Vol. 13 (1), pp. 2885. Date of Electronic Publication: 2022 May 24.
Autor:
Meehan GR; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., Thomas R; University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia., Al Khabouri S; Division of Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden., Wehr P; University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia., Hilkens CM; Translational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Wraith DC; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Sieghart D; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Bonelli M; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Nagy G; Department of Rheumatology & Clinical Immunology, Semmelweis University, Budapest, Hungary.; Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, Hungary., Garside P; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., Tough DF; GlaxoSmithKline Research and Development, Stevenage, Hertfordshire, UK., Lewis HD; GlaxoSmithKline Research and Development, Stevenage, Hertfordshire, UK., Brewer JM; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK james.brewer@glasgow.ac.uk.
Publikováno v:
Annals of the rheumatic diseases [Ann Rheum Dis] 2021 Oct; Vol. 80 (10), pp. 1268-1277. Date of Electronic Publication: 2021 Aug 11.
Autor:
Ghiboub M; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, 1105 BK Amsterdam, The Netherlands.; Adaptive Immunity Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., Elfiky AMI; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, 1105 BK Amsterdam, The Netherlands.; Adaptive Immunity Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., de Winther MPJ; Department of Medical Biochemistry, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Department of Medicine, Institute for Cardiovascular Prevention (IPEK), 80336 Munich, Germany., Harker NR; Adaptive Immunity Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., Tough DF; Adaptive Immunity Research Unit, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, UK., de Jonge WJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, 1105 BK Amsterdam, The Netherlands.; Department of Surgery, University of Bonn, 53127 Bonn, Germany.
Publikováno v:
Journal of personalized medicine [J Pers Med] 2021 Apr 23; Vol. 11 (5). Date of Electronic Publication: 2021 Apr 23.