Zobrazeno 1 - 10
of 831
pro vyhledávání: '"Df, Easton"'
Autor:
Jr, Perry, Yh, Hsu, Di, Chasman, Ad, Johnson, Elks C, Albrecht E, Il, Andrulis, Beesley J, Gs, Berenson, Bergmann S, Se, Bojesen, Mk, Bolla, Brown J, Je, Buring, Campbell H, Chang-Claude J, Chenevix-Trench G, Corre T, Fj, Couch, Cox A, Czene K, Adamo Ap, D., Davies G, Ij, Deary, Dennis J, Df, Easton, Eg, Engelhardt, Jg, Eriksson, Esko T, Fasching P, Jd, Figueroa, Flyger H, Fraser A, Garcia-Closas M, Gasparini P, Gieger C, Giles G, Guenel P, Hägg S, Hall P, Hayward C, Hopper J, Ingelsson E, kConFab investigators, Sl, Kardia, Kasiman K, Ja, Knight, Jari Lahti, Da, Lawlor, Pk, Magnusson, Margolin S, Ja, Marsh, Metspalu A, Je, Olson, Ce, Pennell, Polasek O, Rahman I, Pm, Ridker, Robino A, Rudan I, Rudolph A, Salumets A, Mk, Schmidt, Mj, Schoemaker, En, Smith, Ja, Smith, Southey M, Stöckl D, Aj, Swerdlow, Dj, Thompson, Truong T, Ulivi S, Waldenberger M, Wang Q, Wild S, Jf, Wilson, Af, Wright, Zgaga L, ReproGen Consortium, Kk, Ong, Jm, Murabito, Karasik D, Murray A
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, vol. 23, no. 9, pp. 2490-2497
Europe PubMed Central
Human Molecular Genetics, vol. 23, no. 9, pp. 2490-2497
Europe PubMed Central
The length of female reproductive lifespan is associated with multiple adverse outcomes, including breast cancer, cardiovascular disease and infertility. The biological processes that govern the timing of the beginning and end of reproductive life ar
Autor:
Rl, Milne, Herranz J, Michailidou K, Joe Dennis, Jp, Tyrer, Mp, Zamora, Ji, Arias-Perez, González-Neira A, Pita G, Alonso MR, Wang Q, Mk, Bolla, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Sl, Neuhausen, Ziogas A, Ca, Clarke, Jl, Hopper, Gs, Dite, Apicella C, Mc, Southey, Chenevix-Trench G, kConFab Investigators, Australian Ovarian Cancer Study Group, Swerdlow A, Ashworth A, Orr N, Schoemaker M, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Il, Andrulis, Ja, Knight, Glendon G, Am, Mulligan, Se, Bojesen, Bg, Nordestgaard, Flyger H, Nevanlinna H, Ta, Muranen, Aittomäki K, Blomqvist C, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Wang X, Je, Olson, Vachon C, Purrington K, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Am, Dunning, Shah M, Guénel P, Truong T, Sanchez M, Mulot C, Brenner H, Ak, Dieffenbach, Arndt V, Stegmaier C, Lindblom A, Margolin S, Hooning M, Hollestelle A, Collée M, Jager A, Cox A, Iw, Brock, Mw, Reed, Devilee P, Ra, Tollenaar, Seynaeve C, Ca, Haiman, Be, Henderson, Schumacher F, Le Marchand L, Simard J, Dumont M, Soucy P, Dörk T, Nv, Bogdanova, Hamann U, Försti A, Rüdiger T, Hu, Ulmer, Pa, Fasching, Häberle L, Ab, Ekici, Mw, Beckmann, Fletcher O, Johnson N, Id, Silva, Peto J, Radice P, Peterlongo P, Peissel B, Mariani P, Gg, Giles, Severi G, Baglietto L, Sawyer E, Tomlinson I, Kerin M, Miller N, Marme F, Burwinkel B, Mannermaa A, Kataja V, Vm, Kosma, Hartikainen J, Lambrechts D, Bt, Yesilyurt, Floris G, Leunen K, Gg, Alnæs, Kristensen V, Al, Børresen-Dale, García-Closas M, Sj, Chanock, Lissowska J, Jd, Figueroa, Mk, Schmidt, Broeks A, Verhoef S, Ej, Rutgers, Brauch H, Brüning T, Yd, Ko, Genica, The Network, Fj, Couch, Ae, Toland, Tnbcc, The, Yannoukakos D, Pd, Pharoah, Hall P, Benítez J, Malats N, Df, Easton
Publikováno v:
Milne, Roger L; Herranz, Jesús; Michailidou, Kyriaki; Dennis, Joe; Tyrer, Jonathan P; Zamora, M Pilar; et al.(2014). A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium.. Human molecular genetics, 23(7), 1934-1946. doi: 10.1093/hmg/ddt581. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5ms055cv
Europe PubMed Central
Europe PubMed Central
Part of the substantial unexplained familial aggregation of breast cancer may be due to interactions between common variants, but few studies have had adequate statistical power to detect interactions of realistic magnitude. We aimed to assess all tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8a9d66b18233466920717ddf234eefcc
http://www.escholarship.org/uc/item/5ms055cv
http://www.escholarship.org/uc/item/5ms055cv
Autor:
Kuschel B, Annika Auranen, Cs, Gregory, Ne, Day, Df, Easton, Ba, Ponder, Am, Dunning, Pd, Pharoah
Publikováno v:
Europe PubMed Central
A substantial proportion of the familial risk of breast cancer may be attributable to genetic variants each contributing a small effect. Polymorphisms in DNA repair genes are good candidates for such low penetrance breast cancer susceptibility allele
Autor:
Am, Dunning, Pd, Ellis, Simon McBride, Hl, Kirschenlohr, Cs, Healey, Pr, Kemp, Rn, Luben, Chang-Claude J, Mannermaa A, Kataja V, Pd, Pharoah, Df, Easton, Ba, Ponder, Jc, Metcalfe
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2c135744919e3173520e384da4675189
http://europepmc.org/abstract/med/12750287
http://europepmc.org/abstract/med/12750287
Autor:
Warren W, Rosalind Eeles, Ba, Ponder, Df, Easton, Averill D, Ma, Ponder, Anderson K, Am, Evans, DeMars R, Love R
Publikováno v:
Europe PubMed Central
Recent studies have demonstrated that families with the Li-Fraumeni syndrome carry inherited point mutations of the p53 gene. In the present study 25 families with strong histories of breast cancer were screened for the presence of such mutations. Po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cd626379466377b355aac21eb4d8038f
http://europepmc.org/abstract/med/1570151
http://europepmc.org/abstract/med/1570151
Autor:
Sa, Gayther, Ka, Foy, Harrington P, Pharoah P, Wd, Dunsmuir, Sm, Edwards, Gillett C, Ardern-Jones A, Dp, Dearnaley, Df, Easton, Ford D, Rj, Shearer, Rs, Kirby, Al, Dowe, Kelly J, Stratton MR, Ba, Ponder, Barnes D, Rosalind Eeles
Publikováno v:
Europe PubMed Central
Predisposition to prostate cancer has a genetic component, and there are reports of familial clustering of breast and prostate cancer. Two highly penetrant genes that predispose individuals to breast cancer (BRCA1 and BRCA2) are known to confer an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a9dcd34e6654bc9714122f85dc18ad0d
http://europepmc.org/abstract/med/10969800
http://europepmc.org/abstract/med/10969800
Autor:
Aa, Al Olama, Kote-Jarai Z, Si, Berndt, Dv, Conti, Schumacher F, Han Y, Benlloch S, Dj, Hazelett, Wang Z, Saunders E, Leongamornlert D, Lindstrom S, Jugurnauth-Little S, Dadaev T, Tymrakiewicz M, Do, Stram, Rand K, Wan P, Stram A, Sheng X, Lc, Pooler, Park K, Xia L, Tyrer J, Ln, Kolonel, Le Marchand L, Rn, Hoover, Mj, Machiela, Yeager M, Burdette L, Cc, Chung, Hutchinson A, Yu K, Goh C, Ahmed M, Govindasami K, Guy M, Tl, Tammela, Auvinen A, Wahlfors T, Schleutker J, Visakorpi T, Ka, Leinonen, Xu J, Aly M, Donovan J, Rc, Travis, Tj, Key, Siddiq A, Canzian F, Kt, Khaw, Takahashi A, Kubo M, Pharoah P, Pashayan N, Weischer M, Bg, Nordestgaard, Sf, Nielsen, Klarskov P, Ma, Røder, Iversen P, Sn, Thibodeau, Sk, Mcdonnell, Dj, Schaid, Jl, Stanford, Kolb S, Holt S, Knudsen B, Ah, Coll, Sm, Gapstur, Wr, Diver, Vl, Stevens, Maier C, Luedeke M, Herkommer K, Ae, Rinckleb, Ss, Strom, Pettaway C, Ed, Yeboah, Tettey Y, Rb, Biritwum, Aa, Adjei, Tay E, Truelove A, Niwa S, Ap, Chokkalingam, Cannon-Albright L, Cybulski C, Wokołorczyk D, Kluźniak W, Park J, Sellers T, Hy, Lin, Wb, Isaacs, Aw, Partin, Brenner H, Ak, Dieffenbach, Stegmaier C, Chen C, El, Giovannucci, Ma J, Stampfer M, Kl, Penney, Mucci L, Em, John, Sa, Ingles, Ra, Kittles, Ab, Murphy, Pandha H, Michael A, Am, Kierzek, Blot W, Lb, Signorello, Zheng W, Albanes D, Virtamo J, Weinstein S, Nemesure B, Carpten J, Leske C, Sy, Wu, Hennis A, As, Kibel, Ba, Rybicki, Neslund-Dudas C, Aw, Hsing, Chu L, Pj, Goodman, Ea, Klein, Sl, Zheng, Batra J, Clements J, Spurdle A, Teixeira MR, Maia S, Slavov C, Kaneva R, Mitev V, Js, Witte, Casey G, Em, Gillanders, Seminara D, Riboli E, Fc, Hamdy, Ga, Coetzee, Li Q, Ml, Freedman, Dj, Hunter, Muir K, Gronberg H, Neal DE, Southey M, Gg, Giles, Severi G, Mb, Cook, Nakagawa H, Wiklund F, Kraft P, Sj, Chanock, Be, Henderson, Df, Easton, Ra, Eeles, Ca, Haiman
Publikováno v:
Europe PubMed Central
CIÊNCIAVITAE
CIÊNCIAVITAE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::aef5347bcf41938155e292d349a08bd4
http://europepmc.org/abstract/med/25217961
http://europepmc.org/abstract/med/25217961
Autor:
Johannesdottir G, Gudmundsson J, Jt, Bergthorsson, Arason A, Ba, Agnarsson, Eiriksdottir G, Ot, Johannsson, Borg A, Sigurður Ingvarsson, Df, Easton, Egilsson V, Rb, Barkardottir
Publikováno v:
Europe PubMed Central
Studies on Icelandic breast cancer families have shown that most of them segregate a 999del5 BRCA2 mutation. Here, we report the frequency of the 999del5 BRCA2 mutation in an Icelandic control population and four different groups of cancer patients d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::28129e3b9c711e99b2531574e7e335dd
http://europepmc.org/abstract/med/8706004
http://europepmc.org/abstract/med/8706004
Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer
Autor:
Mm, Gaudet, Kirchhoff T, Green T, Vijai J, Jm, Korn, Guiducci C, Av, Segrè, McGee K, McGuffog L, Kartsonaki C, Morrison J, Healey S, Om, Sinilnikova, Stoppa-Lyonnet D, Mazoyer S, Gauthier-Villars M, Sobol H, Longy M, Frenay M, Gemo, Study Collaborators, Fbl, Hogervorst, Ma, Rookus, Jm, Collée, Hoogerbrugge N, Kep, Roozendaal, Piedmonte M, Rubinstein W, Nerenstone S, Van Le L, Sv, Blank, Caldés T, de la Hoya M, Nevanlinna H, Aittomäki K, Lazaro C, Blanco I, Arason A, Ot, Johannsson, Rb, Barkardottir, Devilee P, Oi, Olopade, Sl, Neuhausen, Wang X, Zs, Fredericksen, Peterlongo P, Manoukian S, Barile M, Viel A, Radice P, Cm, Phelan, Narod S, Rennert G, Lejbkowicz F, Flugelman A, Il, Andrulis, Glendon G, Ozcelik H, Ae, Toland, Montagna M, D'Andrea E, Friedman E, Laitman Y, Borg A, Beattie M, Sj, Ramus, Sm, Domchek, Kl, Nathanson, Rebbeck T, Ab, Spurdle, Chen X, Holland H, Em, John, Jl, Hopper, Ss, Buys, Mb, Daly, Mc, Southey, Mb, Terry, Tung N, Tv, Overeem Hansen, Fc, Nielsen, Mi, Greene, Pl, Mai, Ana Osorio, Durán M, Andres R, Benítez J, Jn, Weitzel, Garber J, Hamann U, Peock S, Cook M, Oliver C, Frost D, Platte R, Dg, Evans, Lalloo F, Eeles R, Izatt L, Walker L, Eason J, Barwell J, Ak, Godwin, Rk, Schmutzler, Wappenschmidt B, Engert S, Arnold N, Gadzicki D, Dean M, Gold B, Rj, Klein, Fj, Couch, Chenevix-Trench G, Df, Easton, Mj, Daly, Ac, Antoniou, Dm, Altshuler, Offit K
Publikováno v:
Europe PubMed Central
PLoS Genetics
Ignacio Blanco
PLoS Genetics
Ignacio Blanco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06f873f640a23b3ea7090227a8517d2
http://europepmc.org/abstract/PMC/PMC2999983
http://europepmc.org/abstract/PMC/PMC2999983
Autor:
Rosalind Eeles, Warren W, Knee G, Bartek J, Averill D, Stratton MR, Pr, Blake, Dm, Tait, Dp, Lane, Df, Easton
Publikováno v:
Europe PubMed Central
We report a constitutional mutation of codon 273 in exon 8 of the p53 gene. The affected individual has developed multiple independent benign and malignant tumours (tricholemmoma of the scalp, multiple trichoepitheliomata of the face, osteosarcoma of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::af0903b2f12c1eab84b8f4c21958557a
http://europepmc.org/abstract/med/8479749
http://europepmc.org/abstract/med/8479749