Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression

Autor: Miklos Diossy, Viktoria Tisza, Hua Li, Pranshu Sahgal, Jia Zhou, Zsofia Sztupinszki, Denise Young, Darryl Nousome, Claire Kuo, Jiji Jiang, Yongmei Chen, Reinhard Ebner, Isabell A. Sesterhenn, Joel T. Moncur, Gregory T. Chesnut, Gyorgy Petrovics, Gregory T. Klus, Gabor Valcz, Pier Vitale Nuzzo, Dezso Ribli, Judit Börcsök, Aurel Prosz, Marcin Krzystanek, Thomas Ried, David Szuts, Kinza Rizwan, Salma Kaochar, Shailja Pathania, Alan D. D’Andrea, Istvan Csabai, Shiv Srivastava, Matthew L. Freedman, Albert Dobi, Sandor Spisak, Zoltan Szallasi

Publikováno v: npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)

Abstract We analyzed genomic data from the prostate cancer of African- and European American men to identify differences contributing to racial disparity of outcome. We also performed FISH-based studies of Chromodomain helicase DNA-binding protein 1

Externí odkaz: https://doaj.org/article/3508a45a6daf4e298c016ff52086528b

Author Correction: A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus

Autor: Sandor Spisak, Viktoria Tisza, Pier Vitale Nuzzo, Ji-Heui Seo, Balint Pataki, Dezso Ribli, Zsofia Sztupinszki, Connor Bell, Mersedeh Rohanizadegan, David R. Stillman, Sarah Abou Alaiwi, Alan H. Bartels, Marton Papp, Anamay Shetty, Forough Abbasi, Xianzhi Lin, Kate Lawrenson, Simon A. Gayther, Mark Pomerantz, Sylvan Baca, Norbert Solymosi, Istvan Csabai, Zoltan Szallasi, Alexander Gusev, Matthew L. Freedman

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)

Externí odkaz: https://doaj.org/article/0532d1b073b9480fac7a98562e9233a2

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

Autor: Emma Nye, Ben Phillimore, Nicholas McGranahan, Gordon Stamp, Archana Fernando, José I. López, Thomas B.K. Watkins, Hang Xu, Lisa Pickering, Kevin Litchfield, David Nicol, Sharmin Begum, Mariam Jamal-Hanjani, Lewis Au, Sharanpreet Lall, Lavinia Spain, Mary Varia, Nicolai Juul Birkbak, Steve Hazell, Eva Grönroos, Nicholas M. Luscombe, Mark Stares, Martin Gore, Alexander Polson, Aspasia Soultati, Ben Challacombe, Marcin Krzystanek, Nicos Fotiadis, Tim Chambers, Aengus Stewart, Ismaeel Aurangzeb, James Larkin, Dezso Ribli, Adam Huffman, Rachel Rosenthal, Orsolya Pipek, Max Salm, Peter J. Campbell, Charles Swanton, Catherine Horsfield, Samra Turajlic, Mickael Escudero, Bruno Silva, Faiz Jabbar, Thomas J. Mitchell, Zoltan Szallasi, Roland F. Schwarz, Simon Chowdhury, Sarkhara Sharma, Ashish Chandra, Sebastijan Hobor, Stuart Horswell, Wei Xing, Gareth A. Wilson, Sophia Ward, Tim O'Brien, Stefan Boeing, Claudia Eichler-Jonsson, Javier Herrero, Andrew Rowan, Nik Matthews, István Csabai, Peter Van Loo, Jonathan C. Smith, Carolina Navas, Greg Elgar, Joanna Lynch, Marta Costa, Sarah Rudman, Rosalie Fisher

Publikováno v: Turajlic, S, Xu, H, Litchfield, K, Rowan, A, Horswell, S, Chambers, T, O'Brien, T, Lopez, J I, Watkins, T B K, Nicol, D, Stares, M, Challacombe, B, Hazell, S, Chandra, A, Mitchell, T J, Au, L, Eichler-Jonsson, C, Jabbar, F, Soultati, A, Chowdhury, S, Rudman, S, Lynch, J, Fernando, A, Stamp, G, Nye, E, Stewart, A, Xing, W, Smith, J C, Escudero, M, Huffman, A, Matthews, N, Elgar, G, Phillimore, B, Costa, M, Begum, S, Ward, S, Salm, M, Boeing, S, Fisher, R, Spain, L, Navas, C, Grönroos, E, Hobor, S, Sharma, S, Aurangzeb, I, Lall, S, Polson, A, Varia, M, Horsfield, C, Fotiadis, N, Pickering, L, Schwarz, R F, Silva, B, Herrero, J, Luscombe, N M, Jamal-Hanjani, M, Rosenthal, R, Birkbak, N J, Wilson, G A, Ribli, D, Pipek, O, Krzystanek, M, Csabai, I, Szallasi, Z I, Gore, M, McGranahan, N, Van Loo, P, Campbell, P, Larkin, J & Swanton, C 2018, ' Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal ', Cell, vol. 173, no. 3, e11, pp. 595-610 . https://doi.org/10.1016/j.cell.2018.03.043
Addi. Archivo Digital para la Docencia y la Investigación
instname

The evolutionary features of clear-cell renal cell carcinoma (ccRCC) have not been systematically studied to date. We analyzed 1,206 primary tumor regions from 101 patients recruited into the multi-center prospective study, TRACERx Renal. We observe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d622d9e406e6e2589f5c1f9901f920d3
https://orbit.dtu.dk/en/publications/0283a41f-f3c8-4e43-bf37-e06dbf418c61

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

A comprehensive survey of the mutagenic impact of common cancer cytotoxics

Autor: Nnennaya Kanu, Dávid Szüts, Bernadett Szikriszt, Orsolya Pipek, Gábor E. Tusnády, János Molnár, Zoltan Szallasi, Marcin Krzystanek, Zoltán Szeltner, Dezso Ribli, Ádám Póti, Charles Swanton, István Csabai

Publikováno v: Szikriszt, B, Poti, A, Pipek, O, Krzystanek, M, Kanu, N, Molnar, J, Ribli, D, Szeltner, Z, Tusnady, G E, Csabai, I, Szallasi, Z I, Swanton, C & Szuts, D 2016, ' A comprehensive survey of the mutagenic impact of common cancer cytotoxics ', Genome Biology, vol. 17, 99 . https://doi.org/10.1186/s13059-016-0963-7
Genome Biology

Background Genomic mutations caused by cytotoxic agents used in cancer chemotherapy may cause secondary malignancies as well as contribute to the evolution of treatment-resistant tumour cells. The stable diploid genome of the chicken DT40 lymphoblast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940938a119d56c5d213114c3c0833529
https://orbit.dtu.dk/en/publications/1f45e87b-9ed2-41c6-bd83-6552b579848b