Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Dezső Szikra"'
Autor:
Dániel Szücs, Judit P. Szabó, Viktória Arató, Barbara Gyuricza, Dezső Szikra, Imre Tóth, Zita Képes, György Trencsényi, Anikó Fekete
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1280 (2023)
Although radiolabeled alpha-melanocyte stimulating hormone-analogue NAPamide derivatives are valuable melanoma-specific diagnostic probes, their rapid elimination kinetics and high renal uptake may preclude them from being used in clinical settings.
Externí odkaz:
https://doaj.org/article/239947dec2ce4685ab9b018181f7ad52
Autor:
Zita Képes, Viktória Arató, Judit P. Szabó, Barbara Gyuricza, Dániel Szücs, István Hajdu, Anikó Fekete, Frank Bruchertseifer, Dezső Szikra, György Trencsényi
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 491 (2023)
Since NGR-tripeptides (asparagine-glycine-arginine) selectively target neoangiogenesis-associated Aminopeptidase N (APN/CD13) on cancer cells, we aimed to evaluate the in vivo tumour targeting capability of radiolabelled, NGR-containing, ANP/CD13-sel
Externí odkaz:
https://doaj.org/article/8ca79fa801d74f959e5e623041f91f7f
Autor:
Csaba Csikos, Adrienn Vágner, Gábor Nagy, Ibolya Kálmán-Szabó, Judit P. Szabó, Minh Toan Ngo, Zoltán Szoboszlai, Dezső Szikra, Zoárd Tibor Krasznai, György Trencsényi, Ildikó Garai
Publikováno v:
Diagnostics, Vol 13, Iss 2, p 236 (2023)
Among humanized monoclonal antibodies, bevacizumab specifically binds to vascular endothelial growth factor A (VEGF-A). VEGF-A is an overexpressed biomarker in cervix carcinoma and is involved in the development and maintenance of tumor-associated ne
Externí odkaz:
https://doaj.org/article/061d48f6b31f4c4cbe486fb6af77407b
Autor:
Barbara Gyuricza, Ágnes Szűcs, Judit P. Szabó, Viktória Arató, Zita Képes, Dániel Szücs, Dezső Szikra, György Trencsényi, Anikó Fekete
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2504 (2022)
Given that galectin-3 (Gal-3) is a β-galactoside-binding lectin promoting tumor growth and metastatis, it could be a valuable target for the treatment of Gal-3-expressing neoplasms. An aromatic group introduced to the C-3′ position of lactosamine
Externí odkaz:
https://doaj.org/article/f1525be97eff46a4b568335f6152c85a
Autor:
Dániel Szücs, Tibor Csupász, Judit P. Szabó, Adrienn Kis, Barbara Gyuricza, Viktória Arató, Viktória Forgács, Adrienn Vágner, Gábor Nagy, Ildikó Garai, Dezső Szikra, Imre Tóth, György Trencsényi, Gyula Tircsó, Anikó Fekete
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 666 (2022)
Hypoxia promotes angiogenesis, which is crucial for tumor growth, and induces malignant progression and increases the therapeutic resistance. Positron emission tomography (PET) enables the detection of the hypoxic regions in tumors using 2-nitroimida
Externí odkaz:
https://doaj.org/article/843f4628244a414b8a57736cdc4ebaed
Autor:
Tibor Csupász, Dániel Szücs, Ferenc Krisztián Kálmán, Oldamur Hollóczki, Anikó Fekete, Dezső Szikra, Éva Tóth, Imre Tóth, Gyula Tircsó
Publikováno v:
Molecules, Vol 27, Iss 2, p 371 (2022)
A new pyclen-3,9-diacetate derivative ligand (H23,9-OPC2A) was synthesized possessing an etheric O-atom opposite to the pyridine ring, to improve the dissociation kinetics of its Mn(II) complex (pyclen = 3,6,9,15-tetraazabicyclo(9.3.1)pentadeca-1(15)
Externí odkaz:
https://doaj.org/article/fbadda1cff62406cb069f60f6c3838fa
Autor:
Viktória Forgács, Anikó Fekete, Barbara Gyuricza, Dániel Szücs, György Trencsényi, Dezső Szikra
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 147 (2022)
Cyclotron-produced radiometals must be separated from the irradiated target and purified from other metal impurities, which could interfere with the radiolabeling process. We compared different chromatographic and colorimetric methods to determine th
Externí odkaz:
https://doaj.org/article/26e2b31d06d24e9e845d363fdffdb581
Autor:
Barbara Gyuricza, Judit P. Szabó, Viktória Arató, Noémi Dénes, Ágnes Szűcs, Katalin Berta, Adrienn Kis, Dániel Szücs, Viktória Forgács, Dezső Szikra, István Kertész, György Trencsényi, Anikó Fekete
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2103 (2021)
Tumor hypoxia induces angiogenesis, which is required for tumor cell survival. The aminopeptidase N receptor (APN/CD13) is an excellent marker of angiogenesis since it is overexpressed in angiogenic blood vessels and in tumor cells. Asparagine-glycin
Externí odkaz:
https://doaj.org/article/49aff5b4bfda4999b912985d0154a7ce
Autor:
Barbara Gyuricza, Judit P. Szabó, Viktória Arató, Dániel Szücs, Adrienn Vágner, Dezső Szikra, Anikó Fekete
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 796 (2021)
Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to αvβ3 integrin. This receptor is overexpressed in tumor and tumor en
Externí odkaz:
https://doaj.org/article/e0d02ba351bf4ee284063b9e7e14328e
Autor:
Fátima Lucio-Martínez, David Esteban-Gómez, Laura Valencia, Dávid Horváth, Dániel Szücs, Anikó Fekete, Dezső Szikra, Gyula Tircsó, Carlos Platas-Iglesias
Publikováno v:
Chemical Communications. 59:3443-3446
Non-macrocyclic H4OCTAPA derivatives form highly stable complexes with Bi(iii), but require an appropriate rigid spacer to enhance the inertness of the complex, as demonstrated by radiolabeling studies with 205/206Bi-nuclides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::703886826d879e76640b16fab6703b7e
https://doi.org/10.1039/d2cc06876a
https://doi.org/10.1039/d2cc06876a