Zobrazeno 1 - 10
of 537
pro vyhledávání: '"Dezheng, Huo"'
Autor:
Fangyuan Zhao, Eric Polley, Julian McClellan, Frederick Howard, Olufunmilayo I. Olopade, Dezheng Huo
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-12 (2024)
Abstract Background For patients with breast cancer undergoing neoadjuvant chemotherapy (NACT), most of the existing prediction models of pathologic complete response (pCR) using clinicopathological features were based on standard statistical models
Externí odkaz:
https://doaj.org/article/44007eaca3214f2aa273d160ef974d05
Autor:
Asim Dhungana, Augustin Vannier, Fangyuan Zhao, Jincong Q. Freeman, Poornima Saha, Megan Sullivan, Katharine Yao, Elbio M. Flores, Olufunmilayo I. Olopade, Alexander T. Pearson, Dezheng Huo, Frederick M. Howard
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Given high costs of Oncotype DX (ODX) testing, widely used in recurrence risk assessment for early-stage breast cancer, studies have predicted ODX using quantitative clinicopathologic variables. However, such models have incorporated only sm
Externí odkaz:
https://doaj.org/article/e40732126a064fc38f5beaea91f0150a
Autor:
Jie Ping, Guochong Jia, Qiuyin Cai, Xingyi Guo, Ran Tao, Christine Ambrosone, Dezheng Huo, Stefan Ambs, Mollie E. Barnard, Yu Chen, Montserrat Garcia-Closas, Jian Gu, Jennifer J. Hu, Esther M. John, Christopher I. Li, Katherine Nathanson, Barbara Nemesure, Olufunmilayo I. Olopade, Tuya Pal, Michael F. Press, Maureen Sanderson, Dale P. Sandler, Toshio Yoshimatsu, Prisca O. Adejumo, Thomas Ahearn, Abenaa M. Brewster, Anselm J. M. Hennis, Timothy Makumbi, Paul Ndom, Katie M. O’Brien, Andrew F. Olshan, Mojisola M. Oluwasanu, Sonya Reid, Song Yao, Ebonee N. Butler, Maosheng Huang, Atara Ntekim, Bingshan Li, Melissa A. Troester, Julie R. Palmer, Christopher A. Haiman, Jirong Long, Wei Zheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract African-ancestry (AA) participants are underrepresented in genetics research. Here, we conducted a transcriptome-wide association study (TWAS) in AA female participants to identify putative breast cancer susceptibility genes. We built geneti
Externí odkaz:
https://doaj.org/article/b9834eb3a0344dc2a7b7b629b0f35afc
Autor:
Mojisola M Oluwasanu PhD, Prisca O Adejumo PhD, Yijia Sun MPP, Chidera Onwuka B.Sc, Atara Ntekim MBBS, MSc, Olutosin A Awolude MBBS, MSc, Toyin I Aniagwu PhD, Olayinka A Kotila PhD, Biobele J Brown MBBS, MSc, Godwin I Ogbole MD, MSc, MSCI, Bonaventure S Dzekem MD, MSc, Olufadekemi Ajani MSc, Dezheng Huo MD, PhD, Chinedum P Babalola PhD, Oladosu Ojengbede MBBS, Nazik Hammad MD, MSc, MEHP, Olufunmilayo I Olopade MD
Publikováno v:
Cancer Control, Vol 31 (2024)
Background Cancers, with increasing incidence and mortality rates, constitute a leading public health problem in Nigeria. As the burden of cancer in Nigeria increases, research and quality service delivery remain critical strategies for improved canc
Externí odkaz:
https://doaj.org/article/1e998069f51446bda67081c55b9f8b1f
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Background Although several transcriptome-wide association studies (TWASs) have been performed to identify genes associated with overall breast cancer (BC) risk, only a few TWAS have explored the differences in estrogen receptor-positive (ER
Externí odkaz:
https://doaj.org/article/1149dce07d1b47f78b1ae6632b5b62de
Autor:
Jincong Q Freeman, Fangyuan Zhao, Frederick M Howard, Rita Nanda, Olufunmilayo I Olopade, Dezheng Huo
Publikováno v:
JMIR Cancer, Vol 10, p e55438 (2024)
BackgroundSince the COVID-19 pandemic began, we have seen rapid growth in telemedicine use. However, telehealth care and services are not equally distributed, and not all patients with breast cancer have equal access across US regions. There are nota
Externí odkaz:
https://doaj.org/article/07a2f9bc53624e75b5796ef65872adb6
Autor:
Gary R. Zirpoli, Ruth M. Pfeiffer, Kimberly A. Bertrand, Dezheng Huo, Kathryn L. Lunetta, Julie R. Palmer
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Background Previous work in European ancestry populations has shown that adding a polygenic risk score (PRS) to breast cancer risk prediction models based on epidemiologic factors results in better discriminatory performance as measured by t
Externí odkaz:
https://doaj.org/article/1e1778063b7a4c4fbdfe3b4807a0e2a5
Autor:
Minoru Miyashita, Joshua S. K. Bell, Stephane Wenric, Ezgi Karaesmen, Brooke Rhead, Matthew Kase, Kristiyana Kaneva, Francisco M. De La Vega, Yonglan Zheng, Toshio F. Yoshimatsu, Galina Khramtsova, Fang Liu, Fangyuan Zhao, Frederick M. Howard, Rita Nanda, Nike Beaubier, Kevin P. White, Dezheng Huo, Olufunmilayo I. Olopade
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Endocrine-resistant HR+/HER2- breast cancer (BC) and triple-negative BC (TNBC) are of interest for molecularly informed treatment due to their aggressive natures and limited treatment profiles. Patients of African Ancestry (AA) ex
Externí odkaz:
https://doaj.org/article/006ca307fd264a2eaf4c46f5adf6c1f6
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-4 (2023)
Abstract OncotypeDX and MammaPrint assays have not been validated to predict pathologic complete response (pCR) to neoadjuvant chemotherapy (NACT) in early-stage breast cancer patients. We analyzed the 2010–2019 National Cancer Database and found t
Externí odkaz:
https://doaj.org/article/fcf5b6d032d846e59fd53893a6f5bc5f
Autor:
Frederick M. Howard, James Dolezal, Sara Kochanny, Galina Khramtsova, Jasmine Vickery, Andrew Srisuwananukorn, Anna Woodard, Nan Chen, Rita Nanda, Charles M. Perou, Olufunmilayo I. Olopade, Dezheng Huo, Alexander T. Pearson
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-6 (2023)
Abstract Gene expression-based recurrence assays are strongly recommended to guide the use of chemotherapy in hormone receptor-positive, HER2-negative breast cancer, but such testing is expensive, can contribute to delays in care, and may not be avai
Externí odkaz:
https://doaj.org/article/cc07ebb96cad409bab31f1a7e6989311