Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dezhen Tu"'
Autor:
Sheng Song, Dezhen Tu, Chengbo Meng, Jie Liu, Belinda Wilson, Qingshan Wang, Yen-Yu Ian Shih, Hui-Ming Gao, Jau-Shyong Hong
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Clinical and pathological evidence revealed that α-synuclein (α-syn) pathology seen in PD patients starts in the gut and spreads via anatomically connected structures from the gut to the brain. Our previous study demonstrated that depletion of cent
Externí odkaz:
https://doaj.org/article/de050ff19a674fdcbf95fce7b617833d
Autor:
Yingying Gou, Dan Yang, Taikun Tian, Xingguo Zhu, Raorao Zhang, Jiaqi Ren, Dezhen Tu, Yi Luo, Yuqing Miao, Huan Zhao, Yu Wang, Bin Wei
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hepatocellular carcinoma (HCC) is one of the most common digestive system cancers (DSCs) with a poor prognosis. Zinc‐regulated transporter (ZRT)/iron‐regulated transporter (IRT) like protein transporters (ZIPs) encode membrane transport proteins,
Externí odkaz:
https://doaj.org/article/bbff9c0c61454e0b96e19be87405039a
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-17 (2020)
Abstract Background Exposure to benzo(a)pyrene (BaP) was associated with cognitive impairments and some Alzheimer’s disease (AD)-like pathological changes. However, it is largely unknown whether BaP exposure participates in the disease progression
Externí odkaz:
https://doaj.org/article/19b5db00f1db40dd88ceef7673851d11
Autor:
Zhan Zhao, Yubao Wang, Ran Zhou, Yi Li, Yun Gao, Dezhen Tu, Belinda Wilson, Sheng Song, Jing Feng, Jau-Shyong Hong, Jerrel L. Yakel
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-19 (2020)
Abstract Background Sepsis-associated acute brain inflammation, if unresolved, may cause chronic neuroinflammation and resultant neurodegenerative diseases. However, little is known how the transition from acute to chronic neuroinflammation, which is
Externí odkaz:
https://doaj.org/article/3c2c103d1b204c11948c033c254ee47c
The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-17 (2019)
Abstract Background Metabolic dysfunction and neuroinflammation are increasingly implicated in Parkinson’s disease (PD). The pentose phosphate pathway (PPP, a metabolic pathway parallel to glycolysis) converts glucose-6-phosphate into pentoses and
Externí odkaz:
https://doaj.org/article/b793c0b49bbc4d799f22f33a62c39788
Autor:
Shih-Heng Chen, Shuangyu Han, Chih-Fen Hu, Ran Zhou, Yun Gao, Dezhen Tu, Huiming Gao, Jing Feng, Yubao Wang, Ru-Band Lu, Jau-Shyong Hong
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1202 (2022)
Recent studies suggest that improper resolution of acute neuroinflammation may lead to long-lasting low-grade chronic neuroinflammation and drive progressive neurodegeneration. However, the molecular mechanism underlying the transition from acute to
Externí odkaz:
https://doaj.org/article/fe60fcf208ab44a58c0fad35d2e06ab6
Publikováno v:
Free Radical Biology and Medicine. 200:47-58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c35f035e7c8f9d83a59a6b5352e17d59
https://doi.org/10.1016/j.freeradbiomed.2023.03.001
https://doi.org/10.1016/j.freeradbiomed.2023.03.001
Autor:
Xiaomeng Zhang, Dezhen Tu, Sheng Li, Na Li, Donglai Li, Yun Gao, Lu Tian, Jianing Liu, Xuan Zhang, Jau-Shyong Hong, Liyan Hou, Jie Zhao, Qingshan Wang
Publikováno v:
Free Radical Biology and Medicine. 188:363-374
Current treatment of Parkinson's disease (PD) ameliorates symptoms but fails to block disease progression. This study was conducted to explore the protective effects of SVHRSP, a synthetic heat-resistant peptide derived from scorpion venom, against d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c88365aa00e97bd49691b91bbf35fd8
https://doi.org/10.1016/j.freeradbiomed.2022.06.241
https://doi.org/10.1016/j.freeradbiomed.2022.06.241
Autor:
Yun Gao1,2 yun.gao@nih.gov, Dezhen Tu1,2 dezhen.tu@nih.gov, Ru Yang1 yangru@nicemice.cn, Chun-Hsien Chu2 chunhsienchu@gmail.com, Jau-Shyong Hong2 hong3@niehs.nih.gov, Hui-Ming Gao1,2 gaohm@nju.edu.cn
Publikováno v:
International Journal of Molecular Sciences. 1/15/2020, Vol. 21 Issue 2, p1-15. 15p. 6 Graphs.
The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-17 (2019)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Metabolic dysfunction and neuroinflammation are increasingly implicated in Parkinson’s disease (PD). The pentose phosphate pathway (PPP, a metabolic pathway parallel to glycolysis) converts glucose-6-phosphate into pentoses and generates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4db0a653e842645557c7676586522d
https://doaj.org/article/b793c0b49bbc4d799f22f33a62c39788
https://doaj.org/article/b793c0b49bbc4d799f22f33a62c39788