Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Deyu Fang"'
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Diet has been shown to be associated with rheumatoid arthritis (RA), of which osteoporosis is the most common and important complication, and zinc has been shown to inhibit the inflammatory response, but studies on the relationshi
Externí odkaz:
https://doaj.org/article/b6900426f5a54fbb851112c4e5b6d469
Autor:
Kun Liu, Qiong Gao, Yuzhi Jia, Juncheng Wei, Shuvam Mohan Chaudhuri, Shengnan Wang, Amy Tang, Nikita Lavanya Mani, Radhika Iyer, Yang Cheng, Beixue Gao, Weiyuan Lu, Zhaolin Sun, Bin Zhang, Huiping Liu, Deyu Fang
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110592- (2024)
Summary: Integrins play critical roles in connecting the extracellular matrix and actin. While the upregulation of integrins is thought to promote cancer stemness and metastasis, the mechanisms underlying their upregulation in cancer stem cells (CSCs
Externí odkaz:
https://doaj.org/article/dceb6421bc6d40a59b69cd4521e2b2ec
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116974- (2024)
Over the past decade, immunotherapies have brought about significant changes in how we approach the treatment of various solid tumors and blood-related cancers. However, the effectiveness of checkpoint blockade therapy has been constrained to a rate
Externí odkaz:
https://doaj.org/article/ee05c77f74ee4c57bcf8ad760e493925
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Progress in sequencing technologies and clinical experiments has revolutionized immunotherapy on solid and hematologic malignancies. However, the benefits of immunotherapy are limited to specific patient subsets, posing challenges for broade
Externí odkaz:
https://doaj.org/article/54afb1e197874d9093274e3e7cbc119f
Autor:
Yuan Luo, Chengsheng Mao, Lazaro N. Sanchez‐Pinto, Faraz S. Ahmad, Andrew Naidech, Luke Rasmussen, Jennifer A. Pacheco, Daniel Schneider, Leena B. Mithal, Scott Dresden, Kristi Holmes, Matthew Carson, Sanjiv J. Shah, Seema Khan, Susan Clare, Richard G. Wunderink, Huiping Liu, Theresa Walunas, Lee Cooper, Feng Yue, Firas Wehbe, Deyu Fang, David M. Liebovitz, Michael Markl, Kelly N. Michelson, Susanna A. McColley, Marianne Green, Justin Starren, Ronald T. Ackermann, Richard T. D'Aquila, James Adams, Donald Lloyd‐Jones, Rex L. Chisholm, Abel Kho
Publikováno v:
Learning Health Systems, Vol 8, Iss 3, Pp n/a-n/a (2024)
Abstract Introduction The rapid development of artificial intelligence (AI) in healthcare has exposed the unmet need for growing a multidisciplinary workforce that can collaborate effectively in the learning health systems. Maximizing the synergy amo
Externí odkaz:
https://doaj.org/article/fccb3f4f664548e18079946ab3e1a555
Autor:
Shuangcheng Alivia Wu, Chenchen Shen, Xiaoqiong Wei, Xiawei Zhang, Siwen Wang, Xinxin Chen, Mauricio Torres, You Lu, Liangguang Leo Lin, Huilun Helen Wang, Allen H. Hunter, Deyu Fang, Shengyi Sun, Magdalena I. Ivanova, Yi Lin, Ling Qi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Endoplasmic reticulum (ER)-associated degradation (ERAD) and ER-phagy are two principal degradative mechanisms for ER proteins and aggregates, respectively; however, the crosstalk between these two pathways under physiological settings remai
Externí odkaz:
https://doaj.org/article/55b8edfe9e8d440db2033fcd22bb16d0
Publikováno v:
Chinese Medical Journal, Vol 136, Iss 3, Pp 253-268 (2023)
Abstract. Integrins are a family of transmembrane receptors that connect the extracellular matrix and actin skeleton, which mediate cell adhesion, migration, signal transduction, and gene transcription. As a bi-directional signaling molecule, integri
Externí odkaz:
https://doaj.org/article/a7071b6533fa4fdb9d9dc7bb0aba5884
Autor:
Xiaohan Zhang, Crystal Young, Xiao-Hui Liao, Samuel Refetoff, Mauricio Torres, Yaron Tomer, Mihaela Stefan-Lifshitz, Hao Zhang, Dennis Larkin, Deyu Fang, Ling Qi, Peter Arvan
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
Defects in endoplasmic reticulum (ER) proteostasis have been linked to diseases in multiple organ systems. Here we examined the impact of perturbation of ER proteostasis in mice bearing thyrocyte-specific knockout of either HRD1 (to disable ER-associ
Externí odkaz:
https://doaj.org/article/f043cf75429d4576b8f536e445366994
Publikováno v:
Green Energy and Intelligent Transportation, Vol 2, Iss 3, Pp 100082- (2023)
Accurate simulation of characteristics performance and state of health (SOH) estimation for lithium-ion batteries are critical for battery management systems (BMS) in electric vehicles. Battery simplified electrochemical model (SEM) can achieve accur
Externí odkaz:
https://doaj.org/article/85f2c5e1f0b1432db560ec8a6cea08dc
Mechanisms regulating the loss of Tregs in HUPO mice that develop spontaneous inflammatory arthritis
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106734- (2023)
Summary: T regulatory cells (Tregs) are a potential therapeutic target in many autoimmune diseases including rheumatoid arthritis (RA). The mechanisms responsible for the maintenance of Tregs in chronic inflammatory conditions such as RA are poorly u
Externí odkaz:
https://doaj.org/article/e8297047994749859429bae8fb61939d