Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Dexin Shen"'
Autor:
Zhao Deng, Dexin Shen, Mengxue Yu, Fenfang Zhou, Danni Shan, Yayun Fang, Wan Jin, Kaiyu Qian, Shenjuan Li, Gang Wang, Yi Zhang, Lingao Ju, Yu Xiao, Xinghuan Wang
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Pectolinarigenin (PEC), an active compound isolated from traditional herbal medicine, has shown potential anti-tumor properties against various types of cancer cells. However, its mechanism of action in bladder cancer (BLCA), which is one of
Externí odkaz:
https://doaj.org/article/c812f9c646eb4f6499ae952a069d0aa5
Autor:
Dexin Shen, Zhao Deng, Wei Liu, Fenfang Zhou, Yayun Fang, Danni Shan, Gang Wang, Kaiyu Qian, Mengxue Yu, Yi Zhang, Lingao Ju, Yu Xiao, Xinghuan Wang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-12 (2023)
Abstract Melatonin is a well-known natural hormone, which shows a potential anticancer effect in many human cancers. Bladder cancer (BLCA) is one of the most malignant human cancers in the world. Chemoresistance is an increasingly prominent phenomeno
Externí odkaz:
https://doaj.org/article/7d2baed62041433eb3c5ab80746dfe47
Publikováno v:
Cardiovascular Innovations and Applications, Vol 9, Iss 1, p 956 (2024)
Background: Observational studies have indicated an association between the gut microbiota and the occurrence and progression of aortic aneurysm (AA). However, the causal relationship between the gut microbiota and AA and its subtypes remains unclear
Externí odkaz:
https://doaj.org/article/f500a7cab90042538192f5ba85cf332a
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Prostate cancer (PCa) is one of the most common male malignancies with frequent remote invasion and metastasis, leading to high mortality. Epithelial-mesenchymal transition (EMT) is a fundamental process in embryonic development and plays a key role
Externí odkaz:
https://doaj.org/article/605020be761b4849af2dd3c02645122f
Autor:
Dexin Shen, Yayun Fang, Fenfang Zhou, Zhao Deng, Kaiyu Qian, Gang Wang, Yu Xiao, Lingao Ju, Xinghuan Wang
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background CDCA3 is an important component of the E3 ligase complex with SKP1 and CUL1, which could regulate the progress of cell mitosis. CDCA3 has been widely identified as a proto-oncogene in multiple human cancers, however, its role in p
Externí odkaz:
https://doaj.org/article/af686e22394a465d8112ea4d31def4ea
Autor:
Dexin Shen, Lingao Ju, Fenfang Zhou, Mengxue Yu, Haoli Ma, Yi Zhang, Tongzu Liu, Yu Xiao, Xinghuan Wang, Kaiyu Qian
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Prostate cancer (PCa) is one of the most commonly diagnosed human cancers in males. Nearly 191,930 new cases and 33,330 new deaths of PCa are estimated in 2020. Androgen and androgen receptor pathways played essential roles in the pathogenes
Externí odkaz:
https://doaj.org/article/d739d3ab62b94c67852e9beda3b62f2f
Autor:
Fenfang Zhou, Dexin Shen, Yaoyi Xiong, Songtao Cheng, Huimin Xu, Gang Wang, Kaiyu Qian, Lingao Ju, Xinhua Zhang
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Kidney renal clear cell carcinoma (KIRC) and kidney renal papillary cell carcinoma (KIRP) are the most common RCC types. RCC has high immune infiltration levels, and immunotherapy is currently one of the most promising treatments for RCC. Collagen tr
Externí odkaz:
https://doaj.org/article/27310e7166954fc19348221876c758e5
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1956 (2021)
Acute lung injury (ALI) is an acute hypoxic respiratory insufficiency caused by various intra- and extra-pulmonary injury factors. The oxidative stress caused by excessive reactive oxygen species (ROS) produced in the lungs plays an important role in
Externí odkaz:
https://doaj.org/article/bef4bce1585542f7ab827e3c8ead3f91
Autor:
Wei Liu, Dexin Shen, Lingao Ju, Renjie Zhang, Wenzhi Du, Wan Jin, Kangping Xiong, Gang Wang, Kaiyu Qian, Yi Zhang, Yu Xiao, Xinghuan Wang
Publikováno v:
Oncogene. 41:4606-4617
The transcription factor MYB proto-oncogene like 2 (MYBL2) is critical in regulating gene expression and tumorigenesis. However, the biological function of MYBL2 in bladder cancer (BLCA) remains to be elucidated. Here, we first revealed that MYBL2 wa
Autor:
Dexin Shen, Lingao Ju, Xinghuan Wang, Kaiyu Qian, Gang Wang, Yongwen Luo, Liang Chen, Yu Xiao, Xuefeng Liu
Publikováno v:
Aging (Albany NY)
Clear cell renal cell carcinoma (ccRCC) is a heterogeneous tumor that the underlying molecular mechanisms are largely unclear. This study aimed to elucidate the key candidate genes and pathways in ccRCC by integrated bioinformatics analysis. 1387 dif