Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dewei Cai"'
Autor:
Diane Hoey, Brigitte Birebent, Enkhtsetseg Purev, Sridhar Nair, Rajasekharan Somasundaram, Dorothee Herlyn, Michael J. Mastrangelo, Edith P. Mitchell, Weiping Li, Dewei Cai, Tianqian Zhang, David T. Harris, Nese Akis, Henry C. Maguire
Publikováno v:
Vaccine. 21:1601-1612
Monoclonal rat anti-idiotypic antibody (Ab2) BR3E4 mimicking the colorectal carcinoma (CRC)-associated epitope CO17-1A induced antigen-specific humoral and cellular immune responses in mice and rabbits. Ab2 BR3E4 was administered in a phase I trial t
Autor:
Henry C. Maguire, Sridhar Nair, Diane Hoey, Enkhtsetseg Purev, Dewei Cai, David T. Harris, Edith P. Mitchell, Brigitte Birebent, Rajasekharan Somasundaram, Dorothee Herlyn, Michael J. Mastrangelo, Takashi Koido, Weiping Li
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 127:R27-R33
The colorectal carcinoma (CRC)-associated CO17-1A/GA733 antigen (Ag) has been the target of a phase II/III randomized trial of passive immunotherapy with monoclonal antibody CO17-1A (Ab1), and phase I active immunotherapy trials with polyclonal anti-
Autor:
Francesco M. Marincola, Rajasekharan Somasundaram, Enkhtsetseg Purev, Dewei Cai, Rosemarie Mick, Ted Mayer, Jesse A. Berlin, Andres J. Klein-Szanto, Brigitte Birebent, Angela DeMichele, Darell D. Bigner, Geza Acs, Eric Miller, William H. Wunner, Rolf Swoboda, Carol J. Wikstrand, Laszlo Otvos, Dorothee Herlyn
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 173(10)
Mutated epidermal growth factor receptor (EGF-RvIII, ΔEGF-R, and de2–7 EGF-R) is the result of an 801-bp deletion within the extracellular domain of wild-type EGF-R and is expressed by breast carcinomas, but not by normal breast tissues. EGF-RvIII
Autor:
Dorothee Herlyn, Rolf Swoboda, Katrin Sproesser, L. Jacob, Hans Bender, Rajasekharan Somasundaram, Dewei Cai, Alban Linnenbach, DuPont Guerry, Weiping Li, Marie Paule Kieny, Jan W. Abramczuk, Jian Li, Shaohong Liang
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 171(6)
Attempts to vaccinate against tumors can be hindered by the induction of immunological tolerance to the target Ag as a result of Ag expression on normal tissues. In this study, we find that transgenic mice expressing the melanoma-associated Ag CD63/M
Autor:
Rajasekharan, Somasundaram, Lutz, Jacob, Rolf, Swoboda, Laura, Caputo, Hong, Song, Saroj, Basak, Dimitri, Monos, David, Peritt, Francesco, Marincola, Dewei, Cai, Brigitte, Birebent, Ellen, Bloome, Jin, Kim, Klara, Berencsi, Michael, Mastrangelo, Dorothee, Herlyn
Publikováno v:
Cancer research. 62(18)
Cancer patients often develop CTLs that lyse autologous tumor cells in culture. However, tumors can progress in vivo despite the presence of CTLs. Various mechanisms have been reported to down-modulate CTL functions. In this study, the role of CD4+/C