Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Dewan S. Billal"'
Publikováno v:
Journal of Infection and Chemotherapy. 14:180-187
Acute otitis media (AOM) is the most common disease seen in childhood. Streptococcus pneumoniae, non-typeable Haemophilus influenzae (NTHi), and Moraxella catarrhalis are the most frequent pathogens of all AOM episodes. The high prevalence of drug-re
Autor:
Noboru Yamanaka, Keiji Fujihara, Muneki Hotomi, Kazuma Yamauchi, Jun Arai, Masaki Suzumoto, Toshiki Katsurahara, Satomi Moriyama, Dewan S. Billal
Publikováno v:
European Journal of Pediatrics. 167:401-407
The appropriate clinical applications of pneumococcal polysaccharide vaccines against recent increases in antimicrobial resistant Streptococcus pneumoniae (S. pneumoniae) urgently require accurate analytical methodologies for determining and characte
Autor:
Jun Nagura, Keiji Fujihara, Noboru Yamanaka, Kazuma Yamauchi, Muneki Hotomi, Takayoshi Fukushima, Dewan S. Billal, Masaki Suzumoto, Jun Shimada, Koju Itahashi
Publikováno v:
Vaccine. 25:2478-2484
An animal model of otitis media using chinchillas was developed to evaluate the efficacy of tebipenem pivoxil (TBM-PI) against experimental otitis media. Chinchillas inoculated via the transbullar approach with Streptococcus pneumoniae serogroup 6 we
Autor:
Kazuma Yamauchi, Muneki Hotomi, Intetsu Kobayashi, Masaki Suzumoto, Keiji Fujihara, Noboru Yamanaka, Dewan S. Billal
Publikováno v:
International Journal of Pediatric Otorhinolaryngology. 71:269-274
Summary Objective Heamophilus influenzae (H. influenzae) is an important pathogen responsible for both invasive and non-invasive infectious diseases. While encapsulated type b strain recognized as a major cause of severe invasive diseases, nontypeabl
Publikováno v:
Vaccine. 24:5294-5299
Acute otitis media is one of the most common infectious diseases in children younger than 2 years of age. Immunological studies in young children have revealed that immature antibody-responses to major pathogens, such as S. pneumoniae, H. influenzae,
Publikováno v:
ORL. 68:135-138
The increasing difficulty in the management of pneumococcal acute otitis media in parallel with increases in antimicrobial-resistant strains has led to much interest in pneumococcal capsular types for the adoption of effective prevention by vaccines.
Autor:
Jun Shimada, Dewan S. Billal, Kazuma Yamauchi, Masaki Suzumoto, Keiji Fujihara, Muneki Hotomi, Noboru Yamanaka
Publikováno v:
ORL. 68:139-145
Objective: To evaluate the resistances of Streptococcus pneumoniae to β-lactams developed by stepwise alterations in high-molecular-weight penicillin-binding proteins (PBPs) with a reduced binding affinity of β-lactams. Among the numerous mutations
Autor:
Muneki Hotomi, Jun Shimada, Keiji Fujihara, Kazuma Yamauchi, Noboru Yamanaka, Masaki Suzumoto, Dewan S. Billal
Publikováno v:
The Laryngoscope. 115:317-320
Objective: To evaluate prevalence of macrolide resistant strains and the genotypes of the resistance among Streptococcus pneumoniae isolated from the nasopharynx of children with otitis media. Study Design: Retrospective review. Methods: A total of 8
Autor:
Akihiro Sakai, Dewan S. Billal, Muneki Hotomi, Jun Shimada, Kazuma Yamauchi, Keiji Fujihara, Noboru Yamanaka, Shinji Tamura
Publikováno v:
Acta Oto-Laryngologica. 125:180-183
Younger children tend to harbor more resistant strains because they are exposed to these pathogens more often through contacts with siblings or attendance at day-care centers and are frequently treated with antibiotics. The high prevalence of BLNAR s
Autor:
Masaki Suzumoto, Kazuma Yamauchi, Gary W. Zlotnick, Muneki Hotomi, Keiji Fujihara, Dewan S. Billal, Noboru Yamanaka, Bruce A. Green, Jun Shimada, Yorihiko Ikeda
Publikováno v:
Vaccine. 23:1294-1300
Outer membrane protein P4, together with P6, is highly conserved among all typeable and nontypeable strains of Haemophilus influenzae ( H. influenzae ). Thus, the protein is an attractive antigen for the inclusion in a vaccine against nontypeable H.