Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Devraj Basu"'
Autor:
Malay K. Sannigrahi, Austin C. Cao, Pavithra Rajagopalan, Lova Sun, Robert M. Brody, Lovely Raghav, Phyllis A. Gimotty, Devraj Basu
Publikováno v:
Molecular Oncology, Vol 18, Iss 2, Pp 336-349 (2024)
There is limited guidance on exploiting the genome‐wide loss‐of‐function CRISPR screens in cancer Dependency Map (DepMap) to identify new targets for individual cancer types. This study integrated multiple tools to filter these data in order to
Externí odkaz:
https://doaj.org/article/5a52bfb1fc6c4551869e5a8296b1e1e4
Multiple airway plasmacytomas: A rare cause of proximal airway obstruction requiring tumor debulking
Autor:
Christopher Ghiathi, Ashley N. Barlev, Gabriel C. Caponetti, John P. Plastaras, Devraj Basu, Adam D. Cohen, Kevin C. Ma
Publikováno v:
Clinical Case Reports, Vol 11, Iss 11, Pp n/a-n/a (2023)
Key Clinical Message Extramedullary plasmacytomas (EMP) can present as airway lesions causing central airway obstruction. Though typically solitary, EMPs should be considered in the evaluation of multifocal tracheobronchial tumors. Bronchoscopic tumo
Externí odkaz:
https://doaj.org/article/eee07fe96b79404dbb45fd7690746225
Autor:
Claire D. James, Raymonde O. Otoa, Aya H. Youssef, Christian T. Fontan, Malay K. Sannigrahi, Brad Windle, Devraj Basu, Iain M. Morgan
Publikováno v:
Tumour Virus Research, Vol 18, Iss , Pp 200285- (2024)
HPV + oropharyngeal squamous cell carcinoma (OPC) incidence recently surpassed cervical cancer and is the most common HPV-related cancer in the developed world. HPV16 is in ∼90 % of HPV + OPCs, with episomal genomes in the majority of cases. Most e
Externí odkaz:
https://doaj.org/article/25412f60534049e8a4a58ea3cdbc617f
Autor:
Ryan M. Carey, Derek B. McMahon, Zoey A. Miller, TaeBeom Kim, Karthik Rajasekaran, Indiwari Gopallawa, Jason G. Newman, Devraj Basu, Kevin T. Nead, Elizabeth A. White, Robert J. Lee
Publikováno v:
Molecular Oncology, Vol 16, Iss 7, Pp 1474-1492 (2022)
Better management of head and neck squamous cell carcinomas (HNSCCs) requires a clearer understanding of tumor biology and disease risk. Bitter taste receptors (T2Rs) have been studied in several cancers, including thyroid, salivary, and GI, but thei
Externí odkaz:
https://doaj.org/article/b0ea728648f841bd816c75a4bc14e389
Autor:
Malay K. Sannigrahi, Pavithra Rajagopalan, Ling Lai, Xinyi Liu, Varun Sahu, Hiroshi Nakagawa, Jalal B. Jalaly, Robert M. Brody, Iain M. Morgan, Bradford E. Windle, Xiaowei Wang, Phyllis A. Gimotty, Daniel P. Kelly, Elizabeth A. White, Devraj Basu
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
Therapy with radiation plus cisplatin kills HPV+ oropharyngeal squamous cell carcinomas (OPSCCs) by increasing reactive oxygen species beyond cellular antioxidant capacity. To explore why these standard treatments fail for some patients, we evaluated
Externí odkaz:
https://doaj.org/article/2e2a2366ebb445348cb086698c1327da
Autor:
Christian T. Fontan, Claire D. James, Apurva T. Prabhakar, Molly L. Bristol, Raymonde Otoa, Xu Wang, Elmira Karimi, Pavithra Rajagopalan, Devraj Basu, Iain M. Morgan
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Human papillomaviruses (HPV) are causative agents in ano-genital and oral cancers; HPV16 is the most prevalent type detected in human cancers. The HPV16 E6 protein targets p53 for proteasomal degradation to facilitate proliferation of the HP
Externí odkaz:
https://doaj.org/article/5c1ee0e73e2c4d9dac09803d585872c2
Autor:
Joshua Hatterschide, Paola Castagnino, Hee Won Kim, Steven M Sperry, Kathleen T Montone, Devraj Basu, Elizabeth A White
Publikováno v:
eLife, Vol 11 (2022)
Persistent human papillomavirus (HPV) infection of stratified squamous epithelial cells causes nearly 5% of cancer cases worldwide. HPV-positive oropharyngeal cancers harbor few mutations in the Hippo signaling pathway compared to HPV-negative cancer
Externí odkaz:
https://doaj.org/article/cba4083c22774cf3ae057bc2d8774083
Autor:
Takashi Kijima, Hiroshi Nakagawa, Masataka Shimonosono, Prasanna M. Chandramouleeswaran, Takeo Hara, Varun Sahu, Yuta Kasagi, Osamu Kikuchi, Koji Tanaka, Veronique Giroux, Amanda B. Muir, Kelly A. Whelan, Shinya Ohashi, Seiji Naganuma, Andres J. Klein-Szanto, Yoshiaki Shinden, Ken Sasaki, Itaru Omoto, Yoshiaki Kita, Manabu Muto, Adam J. Bass, J. Alan Diehl, Gregory G. Ginsberg, Yuichiro Doki, Masaki Mori, Yasuto Uchikado, Takaaki Arigami, Narayan G. Avadhani, Devraj Basu, Anil K. Rustgi, Shoji Natsugoe
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Background & Aims: Oropharyngeal and esophageal squamous cell carcinomas, especially the latter, are a lethal disease, featuring intratumoral cancer cell heterogeneity and therapy resistance. To facilitate cancer therapy in personalized medicine, thr
Externí odkaz:
https://doaj.org/article/7488edc6ab024bcda04958703e1f2938
Autor:
Mitsuteru Natsuizaka, Kelly A. Whelan, Shingo Kagawa, Koji Tanaka, Veronique Giroux, Prasanna M. Chandramouleeswaran, Apple Long, Varun Sahu, Douglas S. Darling, Jianwen Que, Yizeng Yang, Jonathan P. Katz, E. Paul Wileyto, Devraj Basu, Yoshiaki Kita, Shoji Natsugoe, Seiji Naganuma, Andres J. Klein-Szanto, J. Alan Diehl, Adam J. Bass, Kwok-Kin Wong, Anil K. Rustgi, Hiroshi Nakagawa
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Notch receptors can exert different roles in cancer. In this manuscript, the authors reveal that Notch1 activation and EMT promote tumor initiation and cancer cell heterogeneity in squamous cell carcinoma, while the repression of Notch3 by ZEB1 limit
Externí odkaz:
https://doaj.org/article/6f8691ad6d324ab0a967f60181be89c5
Autor:
Joseph S. Lu, Austin C. Cao, David Shimunov, Lova Sun, John N. Lukens, Alexander Lin, Roger B. Cohen, Devraj Basu, Steven B. Cannady, Karthik Rajasekaran, Gregory S. Weinstein, Robert M. Brody
Publikováno v:
The Laryngoscope.